Sentences with phrase «when effective drugs»

So it's very hard to hazard a guess (when an effective drug might be developed).

According to their calculations, drug - sensitive HIV strains tend to dominate over drug - resistant strains when the effective drug concentration is low.

Not exact matches

In order for the drug to be cost effective, drugmakers should slash the price of the drug by over two thirds — to $ 4,536, when patients would be spending about $ 100,000 to keep themselves healthy, the researchers wrote in the JAMA article.

Planned Parenthood's effective business model was pioneered by drug pushers - give away freebies in anticipation of bigger - ticket sales when the customer is desperate.

Most American schools today operate according to a philosophy of discipline that has its roots in the 1980s and 1990s, when a belief that schools would be safer and more effective if they allowed for «zero tolerance» of violence, drug use, and other misbehavior led to a sharp rise in school suspensions.

Hypnobirthing teaches the mother to relax and believe that her body is perfectly designed to give birth; when the mother is relaxed her body can release natural painkillers that are far more effective than pharmaceutical drugs.

When combined with fertility drugs (gonadotropins or clomiphene), it can be an effective therapy.

A review of US programmes by the Washington State Institute for Public Policy shows several interventions, including drug treatment programmes, intensive supervision of parolees, and various behaviour management courses can work — and that wraparound services tailored to individuals» needs are most effective of all, when done well.

The Labour MP was the sole challenger to Vaz for the post in June 2015, when she stated: «My aim is fewer victims of crime, effective and fair immigration control, less drug abuse and an end to home grown terrorism.»

The trial of nusinersen was stopped in August when it became clear it was effective, making it unethical not to give the real drug to those on the placebo.

When administering SSRIs, the team saw that the drug first collected in the lipid rafts, and afterward, the critical GαS protein moved out of the rafts, freeing it up and making the protein more effective.

When diseases like cancer and AIDS are impacting millions of people each year and rare but deadly infections like Ebola are moving faster than treatment, the race to make effective drugs becomes a sprint.

When Gupta's team added salinomycin to cultured human breast - cancer cells, it was about 100 times as effective at killing the cancer stem cells as popular anti-cancer drug, paclitaxel.

It was the most effective drug available for tonic - clonic (grand mal) seizures until 1938, when Dilantin, a far less sedating drug, displaced it.

When patients take too many unnecessary antibiotics it inches us ever closer to a world where essential drugs are no longer effective.

That's the thinking behind some strategies to effectively eradicate latent reservoirs of HIV — thought to be the virus's last stand when under attack from increasingly effective drug cocktails.

When you get to cancers like breast, prostate and kidney, which have smaller numbers of mutations, the drugs aren't quite as effective.

The effective drugs that the researchers identified when they compared the cancers inhibit pathways normally involved in healing, suggesting that wound repair pathways might somehow be involved in the origin of the cancers.

A key to the study is an understanding that using two, three or more antibiotics in combination does not necessarily make the drugs more effective in combating bacteria — in fact, in many cases, their effectiveness is actually reduced when drugs are used together — so the combinations must be chosen carefully and systematically.

When this article was first published, the number of generations for which the drug is effective was printed incorrectly.

It is often argued that progress in drug research has been hampered by the fact that the disease can only be diagnosed when it is too late for an effective intervention.

«For example, a non-blind trial of a new drug might conclude that it is way more effective than a placebo, when in fact the drug's true effect is rather modest, simply because the researchers» expectations biased the results.»

They report that the test can detect significant drops in the metabolic activity levels of all three types of tumors within 72 hours when exposed to an effective drug whereas tumors that were resistant to a drug show no change.

When all the evidence is weighed together, Prozac, Paxil, and other such popular pills seem to be at best weakly effective against depression — an argument Kirsch presses in his new book, The Emperor's New Drugs.

Its weapon is a moderately effective vaccine created in the early 1990s and then shelved when drug treatment proved successful.

Currently available antiviral drugs inhibit influenza virus replication, but they are not typically effective when given to patients as little as 2 days after infection.

We've also found that when these drugs are used in combinations, they don't reach high enough concentrations within the brain tumor to be effective.

When patient co-pays were covered, doctors were more than 30 percent more likely to prescribe the more effective drug.

When that happens, patients have to switch to a new drug combination that can be less effective than the previous treatment.

The treatment was even more effective when combined with celecoxib, a COX - 2 non-steroidal anti-inflammatory drug already approved for treating some forms of arthritis and pain.

In the Cancer Cell article, the researchers describe how various anticancer drugs, including cisplatin and the targeted therapy vemurafenib, which targets melanomas with the BRAF mutation, become more effective when co-delivered with phenformin.

Last May, a group of advisers to the Food and Drug Administration concluded that Halcion was safe and effective when used correctly, but that the warning on the label should be strengthened.

Discouraged by recent findings that antiviral drugs such as zidovudine (AZT), ddI and ddC are less effective than had been hoped, many people with HIV, and their doctors, are now confused about how and when to use them.

Last week, Lin Zhang, MD, an associate professor of Obstetrics and Gynecology, described in Science Translational Medicine, how his team treated therapy resistant cancer cells to renew their sensitivity to PARP inhibitors, a class of drugs that, when effective, prevent cancer cells from keeping up with DNA repair, causing them to eventually die.

The drugs were effective when used alone or in combination with other classes of antifungals.

As a result, Shaw's team has begun another clinical trial with a more potent ALK inhibitor — LDK378, a drug made by Novartis — that might take over when Xalkori becomes less effective.

The widely - used drug, doxorubicin, is effective in fighting cancer but can be toxic to the heart when higher doses are needed.

It's quite another thing when you're ill and don't have the means to come by effective, safe drugs.

When drugs aren't effective for treating atrial fibrillation, cardiologists may use a procedure called catheter ablation to cauterize, or burn, the heart tissue that's the source of the electrical misfire.

When we go to the doctor, we assume that the drugs he or she prescribes have been carefully tested to make sure they are both safe and effective.

AT RISK Recent studies have found that Truvada, a drug to prevent HIV infection in people at risk of exposure to the virus, is effective when taken daily.

Importantly, researchers found that the drugs are only effective when administered directly into a vein (intravenous), rather than the more commonly used technique of administering the drugs directly into bone marrow (intraosseous).

When matched with patient records, iPSCs and iPSC - derived target cells may be able to predict a patient's prognosis and whether or not a given drug will be effective for him or her.

The drugs aren't effective when given through an intraosseous line (directly into the bone marrow) in witnessed cases.

When given earlier, the drugs are more effective in supporting survival than when they are not giWhen given earlier, the drugs are more effective in supporting survival than when they are not giwhen they are not given.

Dr. Levin's lab is investigating a new class of drugs that are highly effective at keeping RGCs alive when the optic nerve is damaged by glaucoma.

The researchers say the findings provide an explanation for recent evidence showing that anti-angiogenesis drugs such as Avastin can be much more effective when combined with chemotherapy.

The early intervention strategy is most frequently used for drug testing in AD because drug candidates assayed in AD transgenic mice at the stage when pathology is already present are generally less effective [27 — 30].

Clinical trials are stopped early when results are so clear that it would be unethical to continue treating patients on the control arm with the less effective drug.

The tests are based on research conducted by Columbia University Irving Medical Center (CUIMC) investigators — and could pave the way for a more precise approach to cancer therapy and help find effective drugs when conventional approaches to precision medicine have failed.