Sentences with phrase «when high doses»

When high doses of flavonoids are taken, all cell proliferation is inhibited; but this does not harm normal cells which can simply «rest» — however, cancer cells can not survive in the resting state.

This was precisely the school of thought in the all - too recent dark ages of training science, when high doses of vitamin C were the state of the art in periworkout supplementation.

Therefore, more information is needed concerning long - term supplementation, particularly when high doses are used.

When high doses of ibuprofen prescribed by her doctors only made her ears ring, Steelsmith turned elsewhere — to all - natural medicine.

This information is a result of the decrease in malondialdehyde concentrations that occur when high doses of onion juice were given to the subjects.The researchers suspect that the antioxidants in question are probably selenium compounds found in onions, and phenols such as quercetin and isorhamnetin.

Transient liver toxicity is a significant concern in gene therapy, when high doses are required.

Taking supplements during lactation rapidly increases the concentrations of thiamin, riboflavin, and vitamin B - 6 in milk, but increases in vitamin B - 12 levels are small even when high doses are given to the mother for 2 months.

There are also reports of newborn drug toxicity from epidural drugs, especially opiates administered via epidural.80 Newborn opiate toxicity seems more likely when higher dose regimes are used, including those where the mother is able to self - administer extra doses, although it also seems that there are wide differences in individual newborn sensitivity.81

Finally, when a high dose of norepinephrine was administered in lieu of anisomycin, before training, the excess neurotransmitter levels caused amnesia (just as the protein synthesis inhibitor had).

The widely - used drug, doxorubicin, is effective in fighting cancer but can be toxic to the heart when higher doses are needed.

When a higher dose (400 mg) of green coffee bean extract was supplemented, there was an even greater average reduction in blood sugar — up to nearly 28 % at one hour.

Retinal damage has been seen in cats when higher doses, such as might be used to treat a Pseudomonas ear infection, are used.

When higher doses are used, interactions may occur with amitraz dips and collars (Mitaban ®, Preventic ®), spinosad (Comfortis ™) or valiumor - related tranquilizers.

When higher doses are used or if use is chronic (ie.

When higher doses are used (ie.

When higher doses are used, as in mange or mite treatment, problems can arise if the patient has an undiagnosed P - glycoprotein gene mutation.

Not exact matches

Acrylamide has been linked to cancer in mice and rats when it's put in their drinking water, but only in very high doses.

While the FDA has concluded that pesticide residues pose no risk of concern for infants and children, certain kinds of conventionally grown produce contain higher doses of pesticides — even when washed and peeled — which means you should prioritize buying them organic.

They're also advised to avoid flying when the sun is having a solar particle event, which can deliver a higher dose of radiation in one flight than is recommended for the entirety of a pregnancy.

Research has shown there is no difference when comparing equal doses of high fructose corn syrup and regular sugar (8, 9, 10).

Cows are often milked during pregnancy, when their estrogen levels are highest, which is why cow's milk can contain such high doses of estrogen.

Having a high dose of multiple medicines in one go is not safe when your body is already under extra strain, and your baby does not have any capability to filter out what is passed to him or her through your blood.

First, the effects are seen when the prenatal exposure was in high doses.

In fact, doctors give premature babies a higher dose of caffeine when treating breathing problems than what would be found in your breast milk.

When people are exposed to high doses of this virus, they can succumb as well.

Once opioids and sedatives have been prescribed, changing the dose must be done gradually and carefully, especially when a patient has been accustomed to higher doses over a longer period of time.

My sense is when you get the dose too high, you are flooding the system, and it's binding to some of the receptors where you don't want it to bind,» says Linmarie Sikich, director of the Adolescent and School - Age Psychiatric Intervention Research Program (ASPIRE) at the University of North Carolina at Chapel Hill, who was not involved in the research.

Normal mice, in contrast, exhibited no symptoms, even when given 10-fold higher doses of the substances.

And when all food was grown in the area, radiation doses were 50 to 200 percent higher around the coal plants.

Johns Hopkins scientists report that rats exposed to high - energy particles, simulating conditions astronauts would face on a long - term deep space mission, show lapses in attention and slower reaction times, even when the radiation exposure is in extremely low dose ranges.

Even more troubling, her study found a link between high blood levels of lycopene's chemical cousin, beta - carotene, and an increased risk of aggressive prostate cancer — not enough to justify avoiding carrots and other food sources of beta - carotene but an ominous sign that not all food - derived compounds are necessarily benign when taken at higher doses.

When H1N1 viruses circulated during the 2013 - 2014 season, the high - dose vaccine was not significantly better than the standard - dose vaccine at preventing deaths.

During the 2012 - 2013 season, when H3N2 viruses were dominant, the high - dose flu vaccine was 36 percent more effective at preventing deaths in the Medicare beneficiaries studied, compared to the standard - dose vaccine.

During the following season (2013 - 2014), when H1N1 viruses dominated and the standard - dose vaccine had better effectiveness than the previous season, the high - dose vaccine was not significantly better at preventing deaths among the Medicare patients studied.

When pregnant rats are exposed to high doses of phthalates, their male offspring are born with deformed genitalia.

Poor Man's Pharmacopoeia A number of common nutrients may help alleviate mental illness when taken in higher - than - normal doses.

The c - MYC pathway appeared to some researchers to be an unlikely therapeutic target for beta cell regeneration because past studies had found it to cause beta cell death when activated in high doses.

However, when participants exercised at an intensity that was greater than 92 % of their HRmax during the high - intensity periods, the effect was even greater than at the lower intensity levels, indicating that there is a dose - response relationship even in the 85 - 95 % high - intensity zone.

When the condition is not responsive to high - dose vasopressors like norepinephrine and vasopressin, it is associated with high mortality, with more than half of these patients dying within 30 days,» Dr. Khanna said.

All of the animals that received high - dose favipiravir were completely protected from lethal infection; animals treated seven or nine days after infection had begun showing signs of disease, but their conditions quickly improved when treatment began.

However, none of the supplements worked very well in animals, even when researchers administered them in repeated, high doses for a month prior to a noise - exposure test, Le Prell notes.

The largest nationwide clinical trial to study high - dose resveratrol long - term in people with mild to moderate Alzheimer's disease found that a biomarker that declines when the disease progresses was stabilized in people who took the purified form of resveratrol.

The body moves quickly when it gets a high dose; injured cells repair the breaks quickly and efficiently, usually within a few hours.

«Thus, when high - dose human milk feedings consisting mostly of donated milk fail to reduce sepsis and are associated with slow growth, these findings are generalized to a mother's own milk as well.»

When dosed with cocaine at either dose, participants were more likely to not use a condom when they had a higher chance of contracting an STI, compared to participants who weren't on cocaWhen dosed with cocaine at either dose, participants were more likely to not use a condom when they had a higher chance of contracting an STI, compared to participants who weren't on cocawhen they had a higher chance of contracting an STI, compared to participants who weren't on cocaine.

For example, participants on the highest dose of cocaine were on average 40 percent likely to wait an hour to use a condom, but the same participants were 60 percent likely to wait that long when given the zero - dose pill.

When they «challenged» these monkeys and four controls with successively higher doses of an AIDS virus for up to 34 weeks, none of the animals that received eCD4 - Ig became infected, whereas all of the untreated ones did.

Spark CEO Jeff Marrazzo says their more potent vector and differences in how the treatment is made, such as the company's use of a surfactant to make sure the vector doesn't stick to the vial when the surgeon injects it, may result in a higher dose of the RPE65 gene getting into retinal cells and long - lasting effects.

Rao's team is now using this data to develop a new approach to forecasting patients» seizure risk, which could allow patients to avoid potentially dangerous activities such as swimming or driving when their seizure risk is highest, and to potentially take steps (such as additional medication doses) to reduce their seizure risk, similar to how people with asthma know to take extra care to bring their inhalers when pollen levels are high.

For example, when controlling for multiple heart disease risk factors (e.g., age, diabetes, high blood pressure), receiving higher doses of doxorubicin -LRB-?