Sentences with phrase «when immune cells»

When immune cells bind with these, it can interfere with their function, reducing your defenses.

Allergies and asthma show up when immune cells release histamines.

When your immune cells begin fighting the invader, surrounding tissues may be damaged by inflammatory chemicals.

«When immune cells begin to produce inflammation, immune regulation becomes deteriorated and it creates an optimal environment for cancer cells to grow,» says Mohamadzadeh.

To that end, she genetically engineered mice to lack a protein that transports cholesterol out of cells in order to analyze experimentally what happens when immune cells remain abnormally packed with cholesterol.

The condition that results when the immune cells of a transplant (usually of bone marrow) from a donor attack the tissues of the person receiving the transplant.

Understanding that process would in turn help explain what goes wrong in an autoimmune disease like type 1 diabetes, when those immune cells go rogue and turn the attack inward.

When these immune cells were then infected by a small number of the pathogenic bacteria, Listeria, the production of Type - 1 interferon massively increased.

This happens when immune cells talk to each other and also, when they kill diseased cells.

«Inflammatory arthritis is caused when immune cells are recruited from the blood into the joint in a highly regulated process controlled by chemoattractants and adhesion receptors,» says Andrew Luster, MD, PhD, chief of the MGH Division of Rheumatology, Allergy and Immunology, director of the CIID and senior author of the report.

When the immune cells were activated, or primed to respond to infection, Xist RNA reappeared in the proper location.

When immune cells attack myelin, nerve cells can't send their signals.

«Inflammation occurs when our immune cells release inflammatory messengers, or cytokines, which is a normal response to disease.

They even found that when an immune cell attaches to another cell it clears out all but the smallest molecules between them.

«Blood cancers develop when immune cell DNA editing hits off - target spots: Team urges consideration of cutting - and - pasting errors when using enzymes for gene modification.»

Not exact matches

The athletic adults also appeared to have healthier and younger - looking immune systems, at least when it came to an organ called the thymus that's responsible for generating key immune cells called T cells.

In December, SQZ partnered with global pharma firm and cancer treatment leader F. Hoffmann - La Roche in a deal that could be worth $ 500 million or more — a large undisclosed upfront payment, and additional sums when SQZ meets certain milestones — to speed up the development of its technology specifically to inject a person's immune cells with a protein to activate a «killer T» cell response to fight off cancer.

Or consider a vaccine that, when injected directly into a tumor, would not only destroy the malignant cells but also stimulate the body's immune system to go after similar tumor cells.

Eating probiotic - rich foods improves our immune systems, helps lessen the gaps between the cells that line our intestinal walls (gaps can be harmful when they become too large), and restores proper balance of microflora in the intestine.

But, when we cut fat too low, we can starve our bodies» cells and deplete them of essential fats that are required for healthy immune function, a hot metabolism, and steady energy.

When it detects anything white blood cells flood her milk and therefore baby has an improved immune response.

Clamping the cord, especially at an early stage, may also cause the extra blood trapped within the placenta to be forced back through the placenta into the mothers blood supply with the third stage contractions.32 33 This feto - maternal haemorrhage (FMH) increases the chance of future blood group incompatibility problems, which occur when the current baby's blood enters the mother's blood stream, causing an immune reaction which can be reactivated in a subsequent pregnancy, destroying the baby's blood cells and causing anaemia or even death.

Potassium is also very important in a diet as it causes certain immune cells to activate when there is an infection in your body.

When you or your child comes in contact with egg proteins, immune system cells (antibodies) recognize them and signal the immune system to release histamine and other chemicals that cause allergic signs and symptoms.

We found that when it comes to cutaneous immunity — specific to skin — the immune system was being obstructed by skin cells that were too prone to producing inflammation responses.

When viral and bacterial infections strike, our bodies respond by commanding B cells within our immune systems to crank out antibodies to battle the invaders.

When the team compared the types of immune cells activated in the fetus with those in the mother, there were clear differences, suggesting that fetuses generate an independent immune response to CMV (Journal of Experimental Medicine, DOI: 10.1084 / jem.20090348).

A pre-clinical study of two drugs designed to boost T cell performance, has revealed the agents, when give in combination, may enhance the immune system's ability to kill melanoma tumors deficient in the tumor suppressor gene PTEN.

When the dendritic cells are activated, they train T cells — their allies in the adaptive arm of the immune system — to attack cancer cells anywhere in the body, whether at the site of the original tumor or distant metastases.

Typically, when the body senses a foreign substance such as a virus or a bacterium, it sends immune cells to attack the invader while also bolstering the immune system as a whole.

«If we learn how to control dendritic cells, we could strengthen our immune response to infection when needed, or weaken the action of certain immune cells that attack the body's own tissues in autoimmune disease.»

When the T cells of your immune system are forced to deal over time with cancer or a chronic infection such as HIV or hepatitis C, they can develop «T cell exhaustion,» becoming less effective and losing their ability to attack and destroy the invaders of the body.

When researchers injected fresh breast cancer cells in the side opposite the original tumor site, the disease didn't recur in any of the mice, as the cancer was rejected by the immune system's memory.

Based on these ex vivo experiments (in cells isolated from patients and then exposed to PD - L1 blocking agents outside of the body), they predict that when actual patients are given PD - L1 blocking agents, their viral load at the time will influence the «net» outcome, i.e., whether the blockage boosts or weakens the overall anti-HIV immune response.

There is evidence to suggest the gene originally controlled stem cells or immune response, and was only later co-opted to defend animals against rogue cells when they became large and long - lived.

When the researchers added a little of this bacterial byproduct to the mix, Fel d 1 activated a specific immune receptor on cells, called Toll - like receptor 4 (TLR4).

Dendritic cells catch invaders and tell the immune system when and how to respond.

When the body senses these particles, it kick - starts specialized immune defenses, including the production of immune cells known as lymphocytes, which learn to recognize and attack viral DNA.

There was another intriguing connection: Acinetobacter are molecular mimics of proteins found in myelin, the nerve cell coating that the immune system attacks in MS.. That suggests the bacteria might trigger immune attacks that hit myelin, too, as when soldiers who inadvertently resemble the enemy get hit by friendly fire.

Last year, researchers at NIAID and elsewhere solved a decade - long mystery when they found that HIV uses a second set of proteins to gain entry into immune cells.

«When we analyzed tissue samples in the lab, we found that exposing white fat to macrophage cells from the immune system inhibited the transformation.»

For example, immune cells could be engineered to patrol a person's body, recording what they see and reporting back when recaptured.

The momentum started building in 2010 when the FDA approved Provenge, a cancer vaccine that rallies male patients» immune systems to attack prostate cancer cells, allowing patients with an advanced form of the cancer to live several months longer.

The experiments indicated that when dectin - 1 recognizes tropomyosin in house dust mites, shrimp or other common allergy - triggering species it suppresses airway cells» production of an immune molecule, IL - 33, which otherwise would promote an allergic response by immune cells.

Type 1 diabetes occurs when the body's immune system destroys the cells making insulin, the substance that enables glucose in the blood to gain access to the body's cells.

«When the multiple myeloma cells come to the new bone sites, the bone immune cells think, «This is one of our neighbor cells,» and therefore do not eliminate them.

When the body detects a virus, cells release interferons, which mount a rapid immune defense.

Hoping to treat the fetus when its immune system was especially primitive and the disease in a nascent stage, doctors infused stem cells into the fetus's abdominal cavity at just 12 weeks» gestation.

The receptor is believed to inhibit the ability of immune cells to autodestruct when they have outlived their usefulness, resulting in higher concentrations of proinflammatory signals (such as TNF) in the intestines of IBD patients.

Analyzing immune cells in umbilical cord blood from 1074 infants, Zhang and colleagues found that babies who showed hyperactive innate immune responses at birth went on to develop a food allergy when tested at age one.