Sentences with phrase «when immune system cells»

It occurs when immune system cells from the donor proliferate and attack the host's tissues.

Not exact matches

The athletic adults also appeared to have healthier and younger - looking immune systems, at least when it came to an organ called the thymus that's responsible for generating key immune cells called T cells.
Or consider a vaccine that, when injected directly into a tumor, would not only destroy the malignant cells but also stimulate the body's immune system to go after similar tumor cells.
Eating probiotic - rich foods improves our immune systems, helps lessen the gaps between the cells that line our intestinal walls (gaps can be harmful when they become too large), and restores proper balance of microflora in the intestine.
When you or your child comes in contact with egg proteins, immune system cells (antibodies) recognize them and signal the immune system to release histamine and other chemicals that cause allergic signs and symptoms.
We found that when it comes to cutaneous immunity — specific to skin — the immune system was being obstructed by skin cells that were too prone to producing inflammation responses.
When viral and bacterial infections strike, our bodies respond by commanding B cells within our immune systems to crank out antibodies to battle the invaders.
A pre-clinical study of two drugs designed to boost T cell performance, has revealed the agents, when give in combination, may enhance the immune system's ability to kill melanoma tumors deficient in the tumor suppressor gene PTEN.
When the dendritic cells are activated, they train T cells — their allies in the adaptive arm of the immune system — to attack cancer cells anywhere in the body, whether at the site of the original tumor or distant metastases.
Typically, when the body senses a foreign substance such as a virus or a bacterium, it sends immune cells to attack the invader while also bolstering the immune system as a whole.
When the T cells of your immune system are forced to deal over time with cancer or a chronic infection such as HIV or hepatitis C, they can develop «T cell exhaustion,» becoming less effective and losing their ability to attack and destroy the invaders of the body.
When researchers injected fresh breast cancer cells in the side opposite the original tumor site, the disease didn't recur in any of the mice, as the cancer was rejected by the immune system's memory.
Dendritic cells catch invaders and tell the immune system when and how to respond.
There was another intriguing connection: Acinetobacter are molecular mimics of proteins found in myelin, the nerve cell coating that the immune system attacks in MS.. That suggests the bacteria might trigger immune attacks that hit myelin, too, as when soldiers who inadvertently resemble the enemy get hit by friendly fire.
«When we analyzed tissue samples in the lab, we found that exposing white fat to macrophage cells from the immune system inhibited the transformation.»
The momentum started building in 2010 when the FDA approved Provenge, a cancer vaccine that rallies male patients» immune systems to attack prostate cancer cells, allowing patients with an advanced form of the cancer to live several months longer.
Type 1 diabetes occurs when the body's immune system destroys the cells making insulin, the substance that enables glucose in the blood to gain access to the body's cells.
Hoping to treat the fetus when its immune system was especially primitive and the disease in a nascent stage, doctors infused stem cells into the fetus's abdominal cavity at just 12 weeks» gestation.
When the immune system is imbalanced, either due to overly - active cells or cells that suppress its function, it causes a wide range of diseases, from psoriasis to cancer.
«Something similar occurs in our bodies when we're infected with these viruses; there are signals our cells detect that let our immune system know all is not well,» he said.
The reaction begins when an antibody activates a component of the immune system known as a mast cell, which then blasts out a barrage of chemicals.
When pathogens infect the cells of the body, the infection sets off a chain reaction involving the immune system that changes the activity, or expression, of hundreds of genes.
When a T cell detects one, it morphs into a fighting machine, zapping invaders with lethal chemicals, multiplying into an army of identical killers or signaling other immune - system troops to join the attack.
Then there's the West Palm Beach symposium, held to recruit participants for a study testing what happens when aging people get infusions of plasma (the fluid part of blood packed with signaling proteins and other molecules but no red or white cells) from young people who've taken a drug meant to activate their immune system.
HIV infects the body by corrupting T cells that are mobilized by the immune system when the virus enters a person's body.
Islet autoimmunity, detected by antibodies that appear when the immune system attacks the islet cells in the pancreas that produce insulin, is a precursor to type 1 diabetes.
Kipnis and his team first suspected a link between the immune system and social behavior when they found that mice lacking T cells, key components of the immune system, show little interest in their peers.
When fighting chronic viral infections or cancers, a key division of the immune system, known as CD8 T cells, sometimes loses its ability to effectively fight foreign invaders.
When we think of how we fight disease, the image of cells in our immune system fending off microbial invaders often comes to mind.
The immune system detects viruses when viral nucleic acids bind protein receptors in immune cells.
In the tea drinkers» immune systems, gamma delta T cells produced five times more infection - fighting interferon when exposed to disease - causing bacteria than did the T cells of the coffee drinkers.
When challenged by a toxin or infection, the immune system screens this population for a match, then swiftly multiplies the clonal cell line that produces the matching antibody.
Effector T cells incite GvHD when they become overactive as the patient's immune system starts to rebuild itself from the donor stem cells.
But when he injected the mice with genetically identical reprogrammed stem cells, their immune systems attacked, destroying the cells.
When the team looked at what gene signatures the RORγt - dependent ILCs expressed, they found high expression of major histocompatibility complex class II (MHCII) protein, which some cells use to display foreign proteins to the immune system and directly interact with T cells.
Because human T cells don't have as many of these brakes, our cells are a hundred times more aggressive than those of chimps when faced with drugs like TGN1412, which work by triggering the immune system.
Tests in mice and nonhuman primates had shown TGN1412 to be safe, but when it was injected into humans — in a dose less than 1/500 of what was given to monkeys — it caused a massive release of infection - fighting T cells that overstimulated the patients» immune systems, resulting in multiple organ failure.
The researchers noticed that in highly infected mice, NK cells produced IL - 10 about 3.5 days into the infection — days later than when they'd produce IFN - gamma, a protein that helps to mount, rather than defuse, the immune system response.
A study of the way malaria parasites behave when they live in human red blood cells has revealed that they can rapidly change the proteins on the surface of their host cells during the course of a single infection in order to hide from the immune system.
But when we get sick, the T cells loosen their hold to let the immune system attack invading pathogens.
When susceptible people come into contact with flakes of cat skin called dander, T cells in their immune systems set off a chemical chain reaction that produces the familiar symptoms of allergy, including sneezing, runny noses, itching and asthma.
When a dendritic cell comes in contact with an antigen that it deems foreign, it carries it to the lymph nodes, where it instructs the rest of the immune system to attack anything in the body displaying that antigen.
These cells are now thought to serve as the immune system's principal sentinels in the skin — when they detect damage signals from nearby wounded skin cells, they summon other, non-skin-resident immune cells to the site of the wound.
It exposes the immune system to only a handful of bacterial proteins, and it may be that exposure to more — as occurred when people were inoculated with the whole - cell vaccine — is more powerful.
When the cancer - causing Epstein - Barr virus moves into a B - cell of the human immune system, it tricks the cell into rapidly making more copies of itself, each of which will carry the virus.
When the animals» immune systems identify a cancer cell, a genetic tweak allows their bodies to launch a massive attack of white blood cells that kills the budding tumor.
When the immune system stumbles upon an unknown foreign invader for the first time, it often takes days before lashing out with full force — a time during which T cells start dividing and differentiating into specialized cells, such as antibody - producing B cells and killer T cells.
Sometimes when the immune system makes small mistakes, the body amplifies its response in a big way: Editing errors in the DNA of developing T and B cells can cause blood cancers.
While immune system cells» purpose is to defend and protect the body, ironically the brain's «call to arms» may cause more harm than good when it instructs immune cells to enter into the brain.
When the altered T cells were delivered back into Olson's veins, his immune system became a cancer - seeking weapon.
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