Sentences with phrase «when microglial»

While it is known that microglia immune activity changes with aging, which response is affected first — the pro-inflammatory or the anti-inflammatory — or, more importantly, when microglial aging begins is not clear, says Jyoti Watters of the University of Wisconsin - Madison and lead investigator of the study.

Indeed, recent data demonstrate that when microglial cells are removed from the brain and cultured in vitro, they rapidly transform into something else.

Not exact matches

Microglial cells normally help with repair in the body, but when over-activated they can promote unhealthy inflammation.

When there is an injury to the brain, microglial cells — the brain's cleaning cells — gather at the site.

«Of course, it is not known when aging - associated changes in microglial activities begin in the human brain, but these results in mice suggest that it may be earlier than we had previously appreciated,» Watters says.