33) Progressive Retinal Atrophy — this disease of the eye is
when the nerve cells at the back of the eyeball slowly degenerate (or fail), which can lead to blindness.
Cognitive dysfunction happens
when nerve cells start to die and there is malfunction in nerve communication, similar to Alzheimer's in humans.
Simply put, neurodegenerative diseases happen
when nerve cells in the brain deteriorate and die.
Alzheimers, for example, occurs
when nerve cells are destroyed and memory formation and recall are consequently lost.
I will talk about our studies investigating what happens
when nerve cells make new connections in vitro, i.e. in cell culture.
There is a significant decrease in the level of calcium
when nerve cells are affected by Parkinson's disease.
When nerve cells receive a signal of pain or other sensation, the signal opens sodium channels and floods the cell with positively charged sodium ions, which positively charge the neurons until the electrochemistry changes enough to inactivate the channels and close them.
When nerve cells are injured so severely, surrounding cells also die off in the hours after the trauma.
The team, led by Mark Mayford, created a mouse with a specific gene that produces the protein hM3Dq
when nerve cells with this gene become active, leaving the protein attached to the cell.
In prior, unrelated experiments, the same species of worm had become hypersensitive to smell
when its nerve cells experienced problems with dopamine signaling, a cellular process that helps control how readily cells can communicate with one another.
«We have shown that pericytes initiate the increase in blood flow seen
when nerve cells become active, so we now know that functional imaging signals are caused by a pericyte - mediated increase of capillary diameter.
«Although, both ketamine and memantine have similar actions
when nerve cells are active, under resting conditions, memantine is less effective in blocking nerve cell communication compared to ketamine, This fundamental difference in their action could explain why memantine has not been effective as a rapid antidepressant» said Dr. Monteggia, who holds the Ginny and John Eulich Professorship in Autism Spectrum Disorders.
Pain or itching sensations begin
when a nerve cell on the surface of the body reacts to a stimulus, starting a chain reaction that moves from cell to cell.
To see what would happen
when nerve cell impulses were heightened, Shatz and postdocs injected rats with a drug that causes seizures.
When a nerve cell is activated, it sends an electrical impulse down its axon to the terminal, which stimulates a vesicle within the terminal to migrate to the terminal's surrounding membrane.
Not exact matches
His research shows that in cases of hearing loss, the ear's
nerve fibers become damaged before the hair
cells do, and
when those synaptic fibers reconnect to the hair
cells, it's possible to regain hearing.
In a similar vein Mr. Percival Lowell writes: «
When we have, as we say, an idea, what happens inside of us is probably something like this: the neural current of molecular change passes up the
nerves, and through the ganglia reaches at last the cortical
cells....
When swelling, bleeding or other products of inflammation occur inside a compartment, the increase in pressure on the capillaries, muscles and
nerves can result in intense pain and loss of oxygenated blood to the muscle and
nerve cells.
To help make ideas about energy more concrete, for example, the new unit will use a variety of analogies from more familiar physical systems (e.g., combustion and charging a cellphone battery) to help students understand those same energy - releasing and energy - requiring chemical reactions and energy transfer
when they occur in living organisms (e.g., cellular respiration, creating a charge across a membrane in mitochondria and
nerve cells) where the reactions are more complex and difficult to observe.
However,
when the researchers grew
nerve cells that had no p75NTR in their observation chamber, they found that virus transport along the axon is less frequent and much slower.
Found in the sensory
nerve cells of vertebrates, TRPM8 typically sends a sensation of cold to the brain
when activated by low temperatures.
It establishes a lifelong infection that leads to sores in affected tissues
when active and hides in
nerve cells during its latent phase.
Studies with mice show that specific
nerve cells get turned on
when they get in their nests — or anything resembling a conventional nest.
Glial
cells in the spine may activate
when pain - related neurons are firing, dosing both limbs with inflammatory substances that may trigger an excitatory response but that may also be toxic to
nerves.
It's easy to understand why you would not want to be consciously aware of the intricacies of your muscle movement, but this can be less intuitive
when applied to your perceptions, thoughts, and beliefs, which are also final products of the activity of billions of
nerve cells.
When new information needs processing, the
nerve cells can develop new synaptic contacts with their neighbouring
cells or strengthen existing synapses.
Scientists long thought the transition from swimming to walking happened
when fish transitioned from sea to land, as
nerve cells gradually activated more and more specific muscles, taking the trunk muscles and wiggling spine out of the equation.
Interestingly, two additional Nature papers released simultaneously with the Regev and Kuchroo team's study revealed that ILC2
cells in the gut also express Nmur1, take on an inflammatory state
when exposed to NMU, and live in close proximity to NMU - producing
nerve cells.
When Lin's team repeated their experiment with
nerve cells, they found that stimulating the quantum dots caused ion channels to open and the
nerve cell to fire.
There was another intriguing connection: Acinetobacter are molecular mimics of proteins found in myelin, the
nerve cell coating that the immune system attacks in MS.. That suggests the bacteria might trigger immune attacks that hit myelin, too, as
when soldiers who inadvertently resemble the enemy get hit by friendly fire.
«The compounds identified in this study,
when administered orally, both reduced the inflammation that is a hallmark of multiple sclerosis and protected against the
nerve cell damage seen in mouse models of the disease,» said Jeffery Haines, PhD, a post-doctoral fellow at Mount Sinai and the study's lead author.
They measured the concentration of calcium ions in the
nerve cells to visualize their activity
when a moth was stimulated with an odor.
When Laura Dugan, a neurologist at Washington University in St. Louis, heard that buckyballs absorb free radicals, she designed experiments to test whether or not buckyballs could slow down
nerve cell death.
Steve: And that the thickness is networks of
nerve cells joining together and then the thinness is discarding of some of those connections
when the brain figures out they don't need them.
When patients had high levels of activated CaM kinase II floating around in their brains,
nerve cells got overstimulated, and symptoms of OCD or a movement disorder could erupt.
The neurotransmitter acetylcholine is released by
nerve cells in the brain
when people or mice are under mild stress or concentrating on learning something new.
Researchers at Georgetown University Medical Center recently discovered that these drugs also interact with specific proteins on the surfaces of
nerve cells — which could also lead to increased pain
when patients wake up.
«Instead of cleaning up
when neurons die, the microglia assume they're under attack
when they see too much
cell death and kill
nerve cells as collateral damage,» says Tanzi, who led the research team.
When syntaxin is folded, though, the bubbles can't stick to it and the
nerve cell can't pass on its signal.
When the protein is unfolded, tiny bubbles filled with neurotransmitters can stick to it, fuse to the inside wall of a
nerve cell and then break free into a synapse.
In separate experiments,
when Rab32 rises in response to stress in the endoplasmic reticulum, or ER, several things happen: The
nerve cell fibers (both axons and the message - receiving dendrites) are shorter, mitochondria are bulkier than normal and their numbers spike.
When immune
cells attack myelin,
nerve cells can't send their signals.
When the optic
nerve is injured, there are tears and swelling in the affected area that causes the
nerve cells to die.
Zwiebel and colleagues scanned the mosquito genome looking for genes similar to those that generate fruit fly odorant receptors, proteins that project from
nerve cells and initiate a biochemical cascade
when they encounter certain molecules in the air.
When they bind a chemical compound drifting through the air, the
nerve cell sends an impulse to the brain, leading ultimately to the perception of a smell.
The same signals that embryonic
cells use to decide whether to become
nerves, skin or bone come into play again
when adult animals are learning whether to become afraid.
When a spinal cord injury takes place, extensions of
nerve cells from the brainstem — the region of the brain where the command and coordination for urination takes place — become disconnected from
cells in the spinal cord that control the muscles that squeeze or relax the bladder and open and close the urethra.
When the command is given, a complex array of
nerves makes sure that the thousands of
cells activate at once, no matter how far they are from the command nucleus.
When a branch at one end of a
nerve cell, or neuron, is stimulated, an electric pulse races toward the main body of the
cell.
When we experimentally increased the expression of the microRNAs in model
nerve cells designed to replicate the conditions of HD, the
cells lived longer, indicating that these miRNAs may promote
cell survival,» explained lead author Richard Myers, PhD, professor of neurology at BUSM.