Sentences with phrase «when old cells»

However, when old cells return to a stem cell - like status, they can carry with them all of the mutations that have accumulated to date, predisposing some of those cells to developing into precancerous lesions.

But now that we know what kinds of changes occur as these cells age, we can ask which of these changes reverse themselves when an old cell goes back to becoming a young cell» — as appeared to be the case when tissues of older mice were exposed to blood from younger mice.

Not exact matches

When Alexandre Cazes hanged himself in a Thai jail cell in July, the 25 - year - old left behind the trappings of a big - league drug dealer: villas, Lamborghinis, a Porsche, bank accounts in Liechtenstein and Switzerland.

Though many older patients won't reach for their cell phones when they have a mysterious ache or a slight fever, notes physician and mHealth expert Good, younger patients will readily flock to services like HealthTap.

When everything... that the solemnity of the day demanded and the congregation in church had been dismissed, we returned to the old man's cell and there we first splendidly refreshed.

Clark was a 22 - year - old who was fatally shot at 20 times by police on March 18 when they mistook his cell phone for a weapon.

It is a bad thing for football reporters who face the potential for delays on public transportation, additional headaches when walking from their hotel to the bar and the stronger likelihood of that woman from Telemundo showing up in her bikini to get stared at by 65 - year - old guys with their cell phones on a clip and a branded polo shirt they got from a gift bag.

Bilirubin is a yellow substance created when the body replaces old red blood cells with new ones causing yellowing of the skin and whites of the eyes.

What ever happened to good old fashioned punishment When the child misbehaves there is NO priveleges, sports, fun activities, friends, TV, cell phones, i - pods or anything.

I barely trust my 12 year old to go running at a park, armed with a cell phone, when I'm in another area of the park.

When Milo was nine months old, he grabbed my old school cell phone and slurped it into his mouth.

Bilirubin is one of the byproducts created when old red blood cells break down.

The senator, famous for preferring to use an old flip phone instead of a smart phone, said Upstate has problems with poor quality when it comes to cell phone network speed, network reliability, data performance, call performance and text performance.

Lawyers for Tawana R. Wyatt, mother of the late India Cummings, name 11 defendants in alleging that jail officials and medical professionals failed to properly care for Cummings, who was 27 years old when rushed from her cell to Buffalo General Medical Center for an unspecified «medical event» on Feb. 17, 2016.

So a 56 - year - old male — to pick a random example — could get some testicular stem cells removed and stored, secure in the knowledge that he'll have plenty of good sperm available when he's 116.

When the stem cells were around three days old, researchers added a cocktail of proteins including Noggin, which suppresses that pathway, and timed doses of retinoic acid, a compound in vitamin A.

They found significant differences in RNA molecules in the cumulus cells of older patients when compared to RNA expressed in cells of patients younger than 35.

When the huntingtin gene is deleted at an age older than four months, these mice appeared to stay healthy, despite having lost their huntingtin genes in cells all over their bodies.

When your telomeres are finally eaten away after many years, your cells begin to show signs of age, and this process may be a key part of what makes us grow old.

When the piglets were 2 days old, the scientists injected fluorescently labeled cell trackers into a key brain area, the subventricular zone (SVZ).

Recent studies suggest that the total loss in brain volume due to atrophy — a wasting away of tissue caused by cell degeneration — between our teen years and old age is 15 percent or more, which means that by the time we're in our seventies, our brains have shrunk to the size they were when we were between 2 and 3 years old.

The scientists converted these cells to a status last experienced when they were part of six - day - old embryos.

When they sequenced the iPS cell lines, they found higher numbers of mitochondrial DNA mutations, particularly in cells from patients older than 60.

However, when the researchers knocked out SIRT1 in endothelial cells of 10 - month - old mice, then put them on a four - week treadmill running program, they found that the exercise did not produce the same gains seen in normal 10 - month - old mice on the same training plan.

The pigment is released when these cells are killed (center) but, 90 days later, is taken back up into new macrophages that have replaced the old ones (right).

But when researchers injected Anas platyrhynchos ducklings at 4, 9, or 14 weeks old with red blood cells from sheep to simulate a parasitic infection, the birds — as adults — explored new items in their environment and approached small orange toys, a color they typically avoid because they seem to associate it with toxic food.

When Dolly was cloned in 1996 from a cell taken from a six - year - old ewe, she became the center of much controversy that still exists today.

To their surprise, they found that when old and young mice were joined, the muscle stem cells in old mice were revitalized.

Even though the reproductive age for humans is around 15 — 45 years old, the precursor cells that go on to produce human eggs or sperm are formed much earlier, when the fertilized egg grows into a tiny ball of cells in the mother's womb.

Remarkably, the same healing effect was produced when B cells from older obese diabetic mice were applied to acute wounds in similarly aged, obese diabetic mice.

When the scientists blocked Treg cells from accumulating in the fat by targeting a molecule that the immune cells require, mice no longer developed type 4 diabetes in old age.

And perhaps, one fine day, scientists will find a way to interfere with whatever mechanism our body uses to know it's time to create new fat cells when the old ones die.

But this process — even when taking skin cells from an older human — doesn't guarantee stem cells with «older» properties.

But Wormser says that thin - film cells have the potential to produce more power over time than the older technology, because they resist the sun's heat better and produce more power when the temperature spikes.

Epigenetic signatures in older cells — patterns of chemical marks on DNA that dictate what genes are expressed when — were reset to match younger signatures in the process.

When the induced pluripotent stem cell method was used, as expected, the patterns in the neurons were indistinguishable between young and old derived samples.

The 30 - year - old was widely celebrated when she and colleagues published two papers in Nature describing a new and surprisingly simple way of creating stem cells, which the researchers dubbed stimulus - triggered acquisition of pluripotency (STAP) cells.

The methyl molecules have the greatest impact during periods of rapid cell division, such as when an embryo is only a few cells old.

Young mice paired with old mice (left chart, two - toned) made fewer new cells in the brain's hippocampus than when paired with another young mouse (yellow).

Using a very sensitive DNA analysis technique that can also be employed when only very small amounts of DNA from old tissue are available, the researchers could compare the two current cell lines with the tumor from which the cell line was established.

Old mice made hundreds more new brain cells when paired with a young mouse (right chart, two - toned) than when paired with an old mouse (teaOld mice made hundreds more new brain cells when paired with a young mouse (right chart, two - toned) than when paired with an old mouse (teaold mouse (teal).

As the cells get older, they acquire clumps of proteins and extra pieces of DNA, but when Angelika Amon at the Massachusetts Institute of Technology and colleagues tracked spores from old and young yeast cells they found that such abnormalities disappeared, meaning all spores had the same lifespan.

When given a young nucleus, older cells still had dysfunctional microtubules.

When stem cells from the old brain are cultured with signals of a young choroid plexus they can divide and form new neurons (red).

Plasma from old mice didn't have a strong effect when injected into young mice genetically engineered to lack VCAM1 in certain blood - brain barrier cells.

But Morrison thinks a little decrepitude might be worth it: «The cells are shutting themselves down when they get old to avoid turning into cancer cells,» he says.

«But what is really amazing is that when you cultivate old stem cells with signals from young fluid, they can still be stimulated to divide — behaving like the young stem cells.»

Rattan joined the Clark group in 1984 and started exploring what happens when skin, bone, and connective tissue cells grow old and enter a state of limbo — called senescence — in which they neither divide nor die (see «More Than a Sum of Our Cells&raqcells grow old and enter a state of limbo — called senescence — in which they neither divide nor die (see «More Than a Sum of Our Cells&raqCells»).

Schöler and his team looked at embryonic mouse clones that were just a few days old to see when and where the Oct4 gene — which helps embryonic cells decide where to go and what to do — is active.

«When people get older or more obese,» Hamdy says, «some of the visceral fat cells mature and become large, lazy, and dysfunctional.»