Sentences with phrase «when photoreceptor cells»

Not exact matches

When light enters the retina, photoreceptor cells translate it into electrical signals.

«If we could perhaps modulate these pathways and prolong survival of photoreceptor cells, we might be able to delay any further degeneration even when intervening at these later stages of disease.»

But when they are nicely aligned with the female, and in the correct position to mate, the photoreceptor cells are totally covered and the response stops, says Arikawa.

When these photoreceptors detect light, they send a signal to specialized neurons in the retina called retinal ganglion cells, or RGCs, which then transmit visual information to the brain by firing electrical pulses along the optic nerve.

The pigment is needed by photoreceptor cells — the retina's light - sending rods and cones — and when RPE65 is mutated, the photoreceptor cells gradually die.

They assessed gene activity at time points known to correspond with key phases of disease: the «induction phase,» the time before the peak level of photoreceptor cell death; the «execution phase,» when the highest rates of photoreceptor cell death occur; and the «chronic phase,» during which photoreceptor cell death continues at somewhat reduced levels.

Typically, when light passes through the transparent tissue of the retina and strikes photoreceptors, they initiate electrochemical signals that propagate forward through a layer of bipolar cells to ganglion cells.

«When horizontal cells are blocked from being formed — the immediate consequence of knocking out Onecut1 — the photoreceptors don't get what they need to survive, so they degenerate and die later on.»

When transplanted to the subretinal space of mice lacking functional photoreceptors, human embryonic stem cells directed toward a retinal lineage integrate into the outer nuclear layer, express photoreceptor markers, and restore a light response as determined by the electroretinogram (ERG)[5].

In particular we are interested to unravel the mechanisms that ensure the maintenance of the apical membrane when exposed to physical stress, e. g. during morphogenesis of epithelial tissues, or when exposed to light stress in photoreceptor cells, using Drosophila and zebrafish as model organisms.

Using the Mfrprd6 model, and others with similar protein localization and phenotypes when mutated, we hope to gain a better understanding of how RPE cells affect photoreceptor development and the process of phagocytosis.

Melatonin production is suppressed when the retinal ganglion cells of the eye detect sunlight and produce the photoreceptor melanopsin.