Sentences with phrase «when tumors form»

This condition, extremely common in middle - aged and senior ferrets, occurs when tumors form in one or both adrenal glands, resulting in the release of hormones that can cause hair loss, itchy skin, anemia, prostate gland enlargement in males (with potential fatal urinary tract obstruction), and bone marrow suppression.

Transitional cell carcinoma occurs when a tumor forms within these cells.

Not exact matches

Similarly, when these cells were injected into mice, the cells in which SLC13A5 was suppressed formed barely discernable tumors compared to the unmanipulated cancer cells.

In the upper panel, tumor cells formed colonization at day 14, while in the lower panel, when the mouse was treated with the compound edelfosine, most of the tumor cells disappeared at day 10 and failed to form colonization at day 14.

This happens particularly often during the stage of embryonic development, but it can also occur in tumors when they form metastases.

Lee and his team uncovered a form of genetic variation in African American tumors, when compared to European American tumors, that may contribute to differences in prostate cancer behavior and treatment.

Often, it is not diagnosed until at a late stage, when many tumors have already formed,» said principal investigator Lucian Chirieac, MD, a thoracic oncology pathologist in the Department of Pathology at BWH and associate professor at Harvard Medical School.

When cancer cells start dividing rapidly to form tumors, these cells are actually reverting to an earlier time in their development when they were supposed to divide rapiWhen cancer cells start dividing rapidly to form tumors, these cells are actually reverting to an earlier time in their development when they were supposed to divide rapiwhen they were supposed to divide rapidly.

«Indeed, when we studied the mice at the embryonic stage, we saw the cells between the muscle fibers expanded explosively and formed tumors early in development,» Hatley said.

When examined under a microscope, the tumors resemble immature embryonic kidneys, leading doctors to conclude that Wilms tumors form when kidney development, normally complete by birth, persists into childhWhen examined under a microscope, the tumors resemble immature embryonic kidneys, leading doctors to conclude that Wilms tumors form when kidney development, normally complete by birth, persists into childhwhen kidney development, normally complete by birth, persists into childhood.

However, when the researchers switched on KRAS in the preclinical models, an entirely different kind of tumor formed, called angiosarcoma.

In tumors formed by human breast cancer cells, DNA damage (brown staining) is increased by simultaneous Olaparib treatment and PGAM1 suppression (right) when compared to either Olaparib treatment (left) or PGAM1 suppression (center) alone.

They also do not form tumors when monitored over many generations.

Furthermore, when injected into live animals, these aberrant cells form tumors.

Furthermore, when the team suppressed STAP - 2, the prostate cancer cells showed reduced proliferation and did not form a tumor when transplanted into mice.

She also collected visceral fat tissue from women undergoing hysterectomies and found that when the fat secretions had more of the FGF2 protein, more of the cells formed cancerous tumors when transferred into mice.

When normal diploid cells lose one or both copies of tumor suppressor genes, cancers can form.

However, cancerous tumors are formed when the immune system is unable to remove these diseased cells.

Foltz realized that when BEX1 is inhibited, cells grow uncontrollably and can form tumors — and researchers hope to develop treatments that target the malfunctioning gene.

When the researchers introduced these microRNAs into mice prone to B - cell lymphoma, tumors formed far faster, and the mice died from their cancers earlier than those without the molecules.

Recently, researchers led by Pier Paolo Pandolfi at Harvard Medical School found that PTEN's tumor suppressing activity becomes elevated when two copies of the protein bind together, forming a dimeric protein.

A section of a head and neck tumor — red and green markers show the proliferation of cancer stem cells — that formed when one of several newly characterized genes, Myh9, was suppressed.

◯ Mouse health records (age of palatable tumor detection, reason for early euthanasia and exclusion of mice, age of mice with fully developed tumor when sacrificed, mice with large tumors formed close to the neck).

At a time when gene therapy has been revived as a potent form of cancer treatment, a new approach would use nanoparticles, rather than viruses, to deliver strands of DNA or RNA to tumors.

Two microRNAs with synergistic effects, one that suppresses tumor growth and another than inhibits tumor promotion, are combined in an RNA triple helix, complexed with a dendrimer to form nanoparticles, which are incorporated with a polymer to form a hydrogel that inhibits tumor growth when applied to the tumor.

The new iPS cells passed the standard tests for pluripotency: They formed tumors called teratomas when injected into immunocompromised mice, and they could differentiate into cells from the three main tissue types in the body, including neurons, muscle and gut epithelium.

According to recent research, the most common solid tumors (that is, cancer that occurs as clusters of cells in or on organs, rather than in liquid form within the blood or lymphatic system) have up to 66 mutations that influence how the cancer cells operate — how fast they divide, whether they are susceptible to the signals that would normally cause a cell to die, when they detach from the main tumor to colonize another organ in the body, when and where they attach blood vessels to healthy tissues.

Colon and rectal cancers (CRC) occur when abnormal cells form tumors in the tissues of those body parts.

However, when these mice were tested for the ability to form tumours after activation of an oncogenic signal that causes colorectal cancer in humans, they showed dramatic resistance to tumor formation.

When injected in an undifferentiated state or left unchecked in a petri dish, they form disgusting teratoma tumors consisting of many features — hair, skin, teeth, etc..

At five months, when tumors had already began to form, there was little inhibitory effect observed when comparing tumor numbers or sizes to control groups.

When the body is overloaded with toxic chemical, physical and mental / emotional stressors it suppresses the immune system and these abnormal cells develop unregulated and form into either slow or fast growing tumors.

If true, then the use of this medicinal mushroom as an adjunct or preventative therapy may help many patients better fight the battle when challenged with tumor - forming cancers.»

In 2011, the Journal of Agriculture and Food Chemistry reported that azodicarbonamide partially degrades when processed with heat and forms trace amounts of semicarbazide — which has been shown to cause cancer tumors.

Cancer shortens the lives of nearly half of all dogs and cats in the U.S. Cancer in pets occurs when the body's immune system can not stop cells from replicating at an abnormally fast, disorderly pace and forming a mass known as a tumor.

Too many vets are still vaccinating in the scruff of the neck - which has been strongly recommended against since the mid-1990s, since tumors that form there are inoperable; whereas a leg can be amputated when cancer invades there, as long as the vaccines are injected far enough away from the body.

Unfortunately, when fatty tumors occur in horses, they can form on a stalk within the abdomen, become twisted, and cause colic.

When mast cells become abnormal, they often form mast cell tumors.

Leiomyosarcoma is when cancerous tumors form in the stomach or intestinal tract.

Some common benign tumors of dogs are the lipomas or fatty tumors that form under the skin of dog's (usually when they are too chubby).

From proper fat and sugar handling in your body (when an animal forms a Lipoma or fatty tumor - they do not handle or «digest» fat properly...) to even neurotransmitter actions in your brain... enzymes are EVERYWHERE.

Immunoglobulin levels can also remain above normal in all forms of autoimmune disease (ref + see ANA) and when tumors have developed in certain bone marrow cells.