Sentences with phrase «where cytosine»
The DNMT3A structure that Song's team cracked explains why mammalian DNA methylation predominantly occurs at «CpG dinucleotides» — DNA locations where cytosine nucleotides are next to guanidine nucleotides.
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In body cells, 99.98 percent of methylation occurs where the DNA sequence has a molecule of cytosine (C) adjacent to a guanine (G).
Since the methylation of cytosine does not alter the DNA sequence, but only influences when and where these proteins are produced, it is considered an epigenetic modification.