The inherited conditions of aortic stenosis (a narrowing above the aortic heart valve or the aortic valve itself), atopy / allergic dermatitis (
skin allergies), gastric dilatation volvulus (bloat / stomach dilation), early onset cataracts (a clouding of the lens inside the eye), dilated cardiomyopathy (enlargement of the chambers of the heart and thinning of the muscle wall), elbow dysplasia (abnormal growth of tissues that leads to malformation and degeneration of the joint), epilepsy (brain seizures), hypothyroidism (underactive production of thyroid hormones), intervertebral disk disease (
problems with the disks between the vertebrae of the spine leading to neurological
problems), and hepatic portosystemic shunt (an abnormal blood circulation
where blood is diverted around the liver rather than into it) are more prevalent in purebred
dogs than in mixed - breed.