I think before they did that it was largely a mystery when and
where ganglion cells dying during the progression of this disease.
Andrew Huberman, PhD (University of California, San Diego): The original CFC team really made some critical contributions to our understanding of how and
where ganglion cells die during glaucoma.
Unfortunately, many of these connections will be to wrong areas, parts of the brain
where the ganglion cell doesn't need to go.
This differs from crustaceans
where ganglia are further apart and connected by long nerves, like the rungs of a rope ladder.
Not exact matches
This can be seen in the colorful lower square,
where measurements of the activity of different retinal
ganglion cells are shown in response to the same stimulation.
This region is
where the neurons of the motor cortex, the basal
ganglia and the thalamus come together.
Apparently the NGF injected into the brain diffused through the motor and sensory roots of the spinal cord and reached the sympathetic chain
ganglia flanking the cord,
where it induced the outgrowth of nerve fibers.
These nerve cells, known as retinal
ganglion cells (RGCs), use electrical impulses to send visual information — entering the eye through the optic nerve — to the brain
where images are perceived.
The second big surprise was that the support cells, so called glial cells, these are the cells that surround
ganglion cells from their —
where their cell body is in the eye all the way back to the brain.