In patients with type 2 diabetes, recent studies have reported that intravenous (i.v.) infusion of LA increases insulin - mediated glucose disposal,
whereas oral administration of LA has only marginal effects.
Whereas synthetic GABA in
oral form has been classically dismissed as of limited benefit due to absorption issues, research has reported value of the
oral administration of GABA derived from Lactobacillus hilgardii fermentation in anxiety reduction in human beings, and antidepressant activity via the
administration of GABA - rich red yeast rice [145, 146].