Sentences with phrase «whether epigenetic changes»

The study authors note that they have not determined whether the epigenetic changes they observed may improve or harm health.

But in that study, the authors could not determine whether the epigenetic changes were a consequence of being overweight or the cause of the obesity in the first place.

In order to work out which is the chicken and which is the egg, i.e. whether the epigenetic changes are a consequence of the disease or if the disease is a result of the changes, the researchers also investigated whether healthy individuals had epigenetic changes caused by age, BMI and raised blood sugar levels.

Mill says twins would need to be scanned regularly throughout life to find out whether epigenetic changes precede the onset of the disorders.

The next step will be to gather more ancient samples from before and after a major environmental change — the end of a glaciation, for example, or the arrival of humans in the New World — to see whether any epigenetic changes correlate with the environmental transition.

Not exact matches

Even if researchers can pick the signals from the noise, they will then have to work out what the epigenetic changes do, and whether they are in fact adaptive — a tall order given how little we know about interpreting epigenetic signals even in modern DNA.

Shen is now researching whether diet has any effect on the epigenetic changes in mice with cancer.

«The coolest thing from an environmental perspective is that we can ask whether diet can influence this epigenetic process,» say Lanlan Shen of Baylor College of Medicine in Houston, Texas, whose group has developed a way to direct where methylation occurs, allowing them to show that epigenetic changes can trigger tumours (see main story).

Epigenetic changes do not alter the information encoded in the DNA sequence itself but determine whether and to what extent specific genes are used by cells.

«The goal was to measure the safety in patients diagnosed with MDS or AML and determine whether the drug changed the patients» epigenetic bookmarks,» explained Dr. Issa.

The results show that the epigenetic pattern in more than 3,000 genes (out of approximately 25,000 that exists in a human being) had changed differentially, depending on whether the participants had eaten saturated fat or polyunsaturated fat.

Yet it is still too early in our investigation into the epigenetics of this complex stress - response system to know for sure whether these molecular changes indicate any real - world risks or benefits.

To identify these epigenetic changes, they examined whether genes had methyl groups attached to them.

Romain Barrès, who studies the genetics of metabolism at the University of Copenhagen, wanted to see whether there was evidence of such epigenetic changes in human sperm.

Epigenetic changes are a hallmark of cancer, but up until now, it has not been known whether these changes on their own are sufficient to push healthy cells down the cancer path.

Grace Kao, associate ethics professor at Claremont School of Theology, in Claremont, California, mentioned additions she will make to her Introduction to Christian Ethics course, such as discussing epigenetic alterations associated with war trauma for a session on war and peace, the science behind shopping and the ways that poverty can change your genes for a segment about economics, and an exploration of whether genes can predict a person's liberalism and conservatism for a session on religion and politics.

The current work shows that changes in the genetic code of a particular gene can control epigenetic marks at different genes, implying that a gene's genetic code can affect whether other genes are turned on and off, which makes it important to understand the function of all genes involved, not just the one with the so - called misspelling.

The focus of the conference was connecting how epigenetics (cellular and physiological phenotypic trait variations that are caused by external or environmental factors that switch genes on and off and affect how cells read genes instead of being caused by changes in the DNA sequence — in other words nutrition and lifestyle choices) impact whether or not an individual actually develops a specific health issue even though they have a SNP mutation.