Not exact matches
Some of the genetic
factors that are being researched right now are multiple genes contributing to the disease (there are about a dozen genes that are leading candidates), and the possibility of
epigenetic interactions (that is, certain genes and other biological molecules that determine
whether and when certain genes present in the body are turned on or off) that may contribute to schizophrenia.
There has been a rapidly increasing interest in
whether environmental
factors modulate the establishment and maintenance of
epigenetic modifications, and thereby affect gene expression and phenotype in humans and wildlife.
Whether these observations reflect causal processes or are confounded by genetic and social
factors remains unclear, although animal (and some human) studies suggest that
epigenetic programming events may be involved.
The focus of the conference was connecting how
epigenetics (cellular and physiological phenotypic trait variations that are caused by external or environmental
factors that switch genes on and off and affect how cells read genes instead of being caused by changes in the DNA sequence — in other words nutrition and lifestyle choices) impact
whether or not an individual actually develops a specific health issue even though they have a SNP mutation.