Sentences with phrase «which gladstone»

This technique, which Gladstone employs frequently, is also a subtle reward for the viewer's physical presence in the gallery; it is hard to imagine these details reading well on Instagram.

«We hope our human model of ALS will help us to move quickly and effectively to identify promising therapeutic candidates for ALS,» said Gladstone Senior Investigator Steve Finkbeiner, MD, PhD, who is also a professor of neurology and physiology at the University of California, San Francisco, with which Gladstone is affiliated.

«We have known that a lack of progranulin is linked to neurodegenerative conditions such as FTD, but the exact mechanism behind that link remained unclear,» said Dr. Farese, who is also a professor at the University of California, San Francisco (UCSF), with which Gladstone is affiliated.

«Fibroblasts make up about 50 % of all cells in the heart and therefore represent a vast pool of cells that could one day be harnessed and reprogrammed to create new muscle,» said Dr. Srivastava, who is also a professor at the University of California, San Francisco, with which Gladstone is affiliated.

«I am honored to be selected as one of the winners of this new prize,» said Dr. Yamanaka, who is also an anatomy professor at the University of California, San Francisco, with which Gladstone is affiliated.

«The power of regenerative medicine is that it can potentially provide an unlimited source of functional, insulin - producing ß - cells that can then be transplanted into the patient,» said Dr. Ding, who is also a professor at the University of California, San Francisco (UCSF), with which Gladstone is affiliated.

«Our next goal is to replicate these experiments and test their safety in larger mammals, such as pigs, before considering clinical trials in humans,» added Dr. Srivastava, who is also a professor at the University of California, San Francisco (UCSF), with which Gladstone is affiliated.

«We knew that Dll4, when activated, directs artery formation, but couldn't pinpoint how it is activated in the first place,» said Dr. Bruneau, who is also a professor of pediatrics at the University of California, San Francisco, with which Gladstone is affiliated.

«We identified that p75NTR is a unique player in glucose metabolism,» said Dr. Akassoglou, who is also an associate professor of neurology at the University of California, San Francisco, with which Gladstone is affiliated.

«About 60,000 Americans are diagnosed with Parkinson's annually, and dopamine - based therapies often do not provide a long - term solution,» said Dr. Kreitzer, who is also an assistant professor of physiology and neurology at UCSF, with which Gladstone is affiliated.

«I am deeply honored to receive this Lifetime Achievement Award,» said Dr. Mucke, who is also a professor of neurology and the Joseph B. Martin Distinguished Professor of Neuroscience at the University of California, San Francisco, with which Gladstone is affiliated.

«As a result, researchers have used the presence of IBs and heightened kinase activity as a proxy for measuring LRRK2's harmful effects, rather than measuring LRRK2 levels directly,» explained Dr. Finkbeiner, who is the associate director of neurological research at Gladstone as well as a professor at the University of California, San Francisco, with which Gladstone is affiliated.

«I am pleased that scientists around the world are using this technology to search for solutions for many diseases, including ALS,» said Dr. Yamanaka, who is also a professor of anatomy at the University of California, San Francisco, with which Gladstone is affiliated.

«Mutations in the gene that produces TDP - 43 can cause this protein to build up in cells,» said Dr. Farese, who is also a professor at the University of California, San Francisco, with which Gladstone is affiliated.

Dr. Finkbeiner is also a professor of neurology and physiology at the University of California, San Francisco, with which Gladstone is affiliated.

«We are truly honored and humbled to be recognized by the Wellcome Trust,» said Dr. Mahley, who is also a professor of medicine at the University of California, San Francisco, with which Gladstone is affiliated.

Dr. Mucke — who is also a professor of neurology and the Joseph B. Martin Distinguished Professor of Neuroscience at the University of California, San Francisco, with which Gladstone is affiliated — wins the award along with Yueming Li, PhD, member and professor at the Sloan - Kettering Institute, and director of the Graduate Program in Pharmacology at Weill Medical College of Cornell University.

«So much about the mechanisms that cause tauopathies is a mystery, in part because traditional approaches — such as post-mortem brain analysis and animal models — give an incomplete picture,» explained Dr. Huang, who is also an associate professor of neurology at UCSF, with which Gladstone is affiliated.

«For the millions of people suffering from Alzheimer's worldwide, we have no effective drug to prevent or reverse memory loss — the hallmark symptom of this ultimately fatal disease,» said Dr. Mucke, who is also a professor of neurology and neuroscience at the University of California, San Francisco (UCSF), with which Gladstone is affiliated.

«People with Parkinson's disease often show signs of depression before the onset of significant movement problems, so it's likely that the neural imbalance in Parkinson's is also responsible for some behavioral changes associated with the disease,» said Dr. Kreitzer, who is also an assistant professor of physiology at the University of California, San Francisco, with which Gladstone is affiliated.

«Next, we hope to examine the DNA of patients living with congenital heart disease, in the hopes that we can pinpoint the specific genetic disruption that caused their heart defect,» said Dr. Bruneau, who is also a professor of pediatrics at the University of California, San Francisco, with which Gladstone is affiliated.

ALS is one of the many neurological diseases on which Gladstone focuses.

«The iPS cells will provide insights into Huntington's disease, helping us to develop new therapies and test drug candidates,» said Dr. Finkbeiner, who is also a professor of neurology and physiology at the University of California, San Francisco, with which Gladstone is affiliated.

«Currently, we have no effective treatments to slow, prevent or halt Alzheimer's, from which more than 5 million people suffer in the United States alone,» said Dr. Mucke, who directs neurological research at Gladstone and is a professor of neuroscience and neurology at the University of California, San Francisco, with which Gladstone is affiliated.

«CMV infects between 50 % and 80 % of adults worldwide and can often be transmitted from mother to child during pregnancy,» said Dr. Weinberger, who is also an associate professor of biochemistry and biophysics at the University of California, San Francisco (UCSF), with which Gladstone is affiliated.

These students come to Gladstone laboratories via admission to graduate programs primarily at the University of California, San Francisco (UCSF), with which Gladstone is academically affiliated.

«It is an honor and a pleasure to receive this award,» said Dr. Greene, who is also a senior investigator at Gladstone and a professor of medicine at the University of California, San Francisco (UCSF), with which Gladstone is affiliated.

«Scientists knew that Arc was involved in long - term memory, because mice lacking the Arc protein could learn new tasks, but failed to remember them the next day,» said Dr. Finkbeiner, who is also a professor of neurology and physiology at the University of California, San Francisco (UCSF), with which Gladstone is affiliated.

«As a long - time member of the AAP, I am honored to represent my colleagues and help guide the association,» said Dr. Greene, who is also a professor of medicine at the University of California, San Francisco (UCSF), with which Gladstone is affiliated.

Dr. Greene is also a professor of medicine, microbiology and immunology at the University of California San Francisco (UCSF), with which Gladstone is affiliated.

«Much like flicking on a light switch, genes get «switched on» at specific intervals to initiate the fundamental biological process of protein synthesis,» said Dr. Weinberger, who is also an associate professor at the University of California, San Francisco (UCSF), with which Gladstone is affiliated.

«This has been an absolutely fascinating voyage of discovery,» said Dr. Greene, who is also a professor of medicine, microbiology and immunology at the University of California, San Francisco, with which Gladstone is affiliated.

«Current treatments, which involve a complex cocktail of antiretroviral (ARV) medications, are fine - tuned to target and destroy active, replicating HIV — but they can't touch the latent virus,» explained Dr. Greene, director of virology and immunology research at Gladstone and professor of medicine at the University of California, San Francisco, with which Gladstone is affiliated.

Not exact matches

I knew I would never be able to amass the literally hundreds of thousands of volumes that Gladstone and Disraeli each left behind when they departed this life, but at its apogee my library was around 20,000 volumes, which in our day, and within the practical material constraints pressing on me, was a fairly estimable hoard.

He was willing to break out of the comforting atmosphere of Tractarianism which would divide into those who would occupy the middle ground: Williams, A. P. Perceval, George Cornish, Thomas Keble; and those who would become High and Dry, such as Edward Churton, Palmer of Worcester, J. T. Coleridge and Joshua Watson, Gladstone and Manning, leaving Pusey as the lonely figurehead.

It captures the greatness of Gladstone; but also provides the insights which only a professional politician can give to the realities of politics at the sharp end.

Bright kept in close touch with Joseph Chamberlain, his colleague in the representation of Birmingham, and in June after much coming and going he voted with 92 other Liberal members against Gladstone's Home Rule Bill, which was defeated by 341 votes to 311.

Variants of Cameron's proposals have been mooted out at various points of constitutional consternation, which stretch back to the time of Gladstone and demands for «home rule all round».

Upon returning to his homeland, he suffered «post-America depression;» he missed the excellent facilities at Gladstone, the likes of which were not readily available in Japan at the time.

«It would really be wonderful if tau reduction turned out to be useful not only in Alzheimer's disease, but also in other disabling neurological conditions for which there currently are no effective treatments,» said senior author Lennart Mucke, MD, the director of the Gladstone Institute of Neurological Disease and a professor of Neurology and Neuroscience at the University of California, San Francisco.

Gladstone et al. investigated the atmosphere of Pluto, which is colder and more compact than expected and hosts numerous extensive layers of haze.

«Interneurons can reroute after spinal cord injuries, which makes them a promising therapeutic target,» said senior author Todd McDevitt, PhD, a senior investigator at Gladstone.

He further explained, «Gladstone's philosophy has been that the pension plan is a retention tool, which is counter to a postdoc's early career goal.»

«With few exceptions, our postdocs receive the exact same benefits as everyone else at Gladstone, which includes employer - paid medical, dental, and vision, and also covers eligible dependents or domestic partners,» said John LeViathan, postdoctoral fellows advisor and human resources manager.

«This identified IFI16 as the DNA sensor, which then sends signals to caspase - 1 and triggers pyroptosis,» says Kathryn M. Monroe, PhD, the Science paper's other lead author, who completed the research while a postdoctoral fellow at Gladstone.

«We have bioengineered micro-scale heart tissues with a method that can easily be reproduced, which will enable scientists in stem cell biology and the drug industry to study heart cells in their proper context,» said first author Nathaniel Huebsch, PhD, a postdoctoral fellow in the Conklin lab at Gladstone.

«This is also a good example of how the basic science being performed here at Gladstone provides a solid foundation with which to prevent, treat and ultimately cure some of the world's most devastating diseases.»

For example, she directs Gladstone's Center for In Vivo Imaging Research, which analyzes high - resolution and cutting - edge in vivo images to monitor molecular changes in the brains of live animals over time.

Gladstone Postdoctoral Fellow Roy Dar, PhD, also contributed to this research, which was supported by the National Institutes of Health, the Pew Charitable Trust, the Center for Nanophase Materials Sciences (United States Department of Energy), the National Science Foundation Graduate Research Fellowship Program and the National Cancer Institutes.

Since 1993, Gladstone has hosted the Distinguished Lecture Series, which features researchers who have made significant contributions to science and medicine, including many Nobel laureates.