Sentences with phrase «which abnormal proteins»

Payne keyed in the symptoms, and the computer program suggested a handful of potential conditions, including a rare disease called amyloidosis, in which abnormal proteins build up in the body, interfering with normal organ function and causing nerve damage.

Not exact matches

The cancerous cells win out over the healthy blood cells in the bone marrow, which in turn leads to kidney problems when the cancer cells make abnormal proteins instead of antibodies.

This can also be connected to «leaky gut», where the intestinal walls become permeable to proteins which make their way into the bloodstream, causing abnormal immune responses, allergies, intolerances and autoimmune issues.

People with the transthyretin amyloidosis have mutations in the DNA of the transthyretin gene, which causes abnormal buildup and deposits of a transport protein called transthyretin in nerve and heart cells.

Coeliac disease is caused by an abnormal reaction to gliadin, a gluten protein found in wheat (and similar proteins of the tribe Triticeae which includes other cultivars such as barley and rye).

The Chilean Rose Tarantula is the source of an important protein used in drugs to stop atrial fibrillation, an abnormal heart rhythm, or cardiac arrhythmia, which can result in death.

In abnormal [PSI +] cells, which are genetically identical to normal cells, the important protein clumps together, and the cells are unable to grow under certain conditions.

Multiple myeloma is preceded by a blood disorder called monoclonal gammopathy of undetermined significance (MGUS) in which abnormal plasma cells produce many copies of an antibody protein.

Of particular interest are the emerging techniques for genomics and proteomics, which allow profiles of gene expression and protein synthesis to be produced and comparisons to be made between normal and abnormal cells, as well as between cells before and after exposure to medicines or toxic chemicals.

This turned out to be a normal protein in the cells of organisms throughout the animal kingdom — but in brains infected with scrapie and related diseases it turns up in both a normal, soluble form and an abnormal, insoluble form which accumulates in deposits that eventually kill the cells.

In most cases, CTE is thought to be caused by repeated blows to the head, which damage brain tissue and lead to a buildup of an abnormal protein called tau, according to the CTE Center.

In the current study, Dr. Santambrogio and her colleagues looked for abnormal accumulations of proteins in the synovial fluid (which bathes the joints) and blood of patients with JIA.

It's thought that the high pressure observed in tumors is a result of these abnormal blood vessels, which leak fluid and proteins into the area between tumor cells, known as the interstitial space.

The disease is largely attributed to an abnormal buildup of proteins, which can form amyloid beta plaques and tangles in the brain that trigger inflammation and result in the loss of brain connections called synapses, the effect most strongly associated with cognitive decline.

Hutchinson - Gilford progeria is caused by a spontaneous mutation during conception in a gene called LMNA, which encodes a protein called prelamin A. Progeria patients experience a buildup of an abnormal version of prelamin A in their cells that, among other changes, distorts the nucleus and alters gene expression.

While toxic protein clumps have long been implicated in neurodegeneration, this new strategy takes aim at abnormal RNA, which forms before toxic proteins in C9ORF72 - related disorders (c9FTD / ALS).

Brodsky was part of a team that developed the modified Ham test that measures levels of components of serum,, a protein - rich liquid in blood, and showed it was effective in diagnosing atypical hemolytic - uremic syndrome (aHUS), a genetic disorder in which abnormal blood clots form in small blood vessels in the kidneys.

For example, Gladstone scientists are researching how autophagy — a process by which cells eliminate abnormal proteins — can help to prevent the destruction of brain cells.

The abnormal plasma cells make M protein, which is sometimes found during a routine blood or urine test.

In prion diseases, which include mad cow disease and Creutzfeldt - Jakob disease, a normal cell protein, PrP, assumes an abnormal shape.

An effective approach to treating HD is lowering the abnormal protein, which may suppress all kinds of its downstream toxicity.

Earlier lab work by the researchers helped explain key mechanisms involved with assisting vitamin D3 to clear the abnormal protein amyloid - beta, which is found within the plaque.

In addition, sugar molecules are bonded to amino acids, which forms abnormal proteins and can potentially damage the eyes, your nerves system, skin, tendons, and membranes.

Dr. Mara De Amici, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy 29th Congress of the European Academy of Allergy and Clinical Immunology, London, June 5 - 9, 2010 Abstract No. 1105 Background Specific foods and food additives can induce adverse gastrointestinal (GI) and cutaneous reactions, including food allergies that involve an abnormal immunologic reaction to food proteins or food intolerance which is not pathogenetically immune - mediated.

Alzheimer's Disease involves the accumulation of abnormal protein — either amyloid beta or Tau protein which gums up the brain system.

As a result the mutated and damaged genes start making abnormal proteins which trigger formation of destructive plagues in the brain and symptoms of AD.

Although there is still a lot to learn about pathogenesis (the mechanism by which a disease is caused) of Alzheimer's yet we know that during Alzheimer's two abnormal proteins are made by mutated genes of the brain cells.

TPE is an apheresis (removal of impurities from blood) treatment in which plasma contaminated with damaging auto - antibodies, toxins or abnormal proteins is separated from the patient's flowing blood and exchanged with donor plasma that is returned to the patient to render the patient less susceptible to or free from immunologic attack or other pathologic processes.

A urinalysis is the examination of urine for abnormal substances such as blood, protein, sugar or white blood cells, which may indicate a UTI.

The new study, published today in the journal PLoS Genetics, identifies abnormal functioning in a gene called PKP2 that encodes the plakophilin - 2 protein, which promotes and maintains a healthy skin barrier.

Cataracts are an abnormal cloudiness of the lens caused by a buildup of protein or pigment in the lens which interferes with normal vision.