Sentences with phrase «which alter levels»

There are also occasional «invasions» which alter levels that you have already completed and provide significantly greater challenge and reward.

When the variables which alter the level stored in the tub are changed (knobs turned) there will be an imbalance between inflow and outflow until the new equalibrium is reached — a equilibrium at which a different level of energy is stored in the tub.

Not exact matches

Actual results, including with respect to our targets and prospects, could differ materially due to a number of factors, including the risk that we may not obtain sufficient orders to achieve our targeted revenues; price competition in key markets; the risk that we or our channel partners are not able to develop and expand customer bases and accurately anticipate demand from end customers, which can result in increased inventory and reduced orders as we experience wide fluctuations in supply and demand; the risk that our commercial Lighting Products results will continue to suffer if new issues arise regarding issues related to product quality for this business; the risk that we may experience production difficulties that preclude us from shipping sufficient quantities to meet customer orders or that result in higher production costs and lower margins; our ability to lower costs; the risk that our results will suffer if we are unable to balance fluctuations in customer demand and capacity, including bringing on additional capacity on a timely basis to meet customer demand; the risk that longer manufacturing lead times may cause customers to fulfill their orders with a competitor's products instead; the risk that the economic and political uncertainty caused by the proposed tariffs by the United States on Chinese goods, and any corresponding Chinese tariffs in response, may negatively impact demand for our products; product mix; risks associated with the ramp - up of production of our new products, and our entry into new business channels different from those in which we have historically operated; the risk that customers do not maintain their favorable perception of our brand and products, resulting in lower demand for our products; the risk that our products fail to perform or fail to meet customer requirements or expectations, resulting in significant additional costs, including costs associated with warranty returns or the potential recall of our products; ongoing uncertainty in global economic conditions, infrastructure development or customer demand that could negatively affect product demand, collectability of receivables and other related matters as consumers and businesses may defer purchases or payments, or default on payments; risks resulting from the concentration of our business among few customers, including the risk that customers may reduce or cancel orders or fail to honor purchase commitments; the risk that we are not able to enter into acceptable contractual arrangements with the significant customers of the acquired Infineon RF Power business or otherwise not fully realize anticipated benefits of the transaction; the risk that retail customers may alter promotional pricing, increase promotion of a competitor's products over our products or reduce their inventory levels, all of which could negatively affect product demand; the risk that our investments may experience periods of significant stock price volatility causing us to recognize fair value losses on our investment; the risk posed by managing an increasingly complex supply chain that has the ability to supply a sufficient quantity of raw materials, subsystems and finished products with the required specifications and quality; the risk we may be required to record a significant charge to earnings if our goodwill or amortizable assets become impaired; risks relating to confidential information theft or misuse, including through cyber-attacks or cyber intrusion; our ability to complete development and commercialization of products under development, such as our pipeline of Wolfspeed products, improved LED chips, LED components, and LED lighting products risks related to our multi-year warranty periods for LED lighting products; risks associated with acquisitions, divestitures, joint ventures or investments generally; the rapid development of new technology and competing products that may impair demand or render our products obsolete; the potential lack of customer acceptance for our products; risks associated with ongoing litigation; and other factors discussed in our filings with the Securities and Exchange Commission (SEC), including our report on Form 10 - K for the fiscal year ended June 25, 2017, and subsequent reports filed with the SEC.

Key support levels ahead for the latter index are 1,905, a 3 percent drop from Friday's close, and then 1,820, a violation of which «would alter the longer - term uptrend of the broader market.»

The franchisees allege that 3G Capital (RBI's parent company) has failed to maintain franchisee relationships, altered the company's rent and royalty structure (which were to be maintained for 5 years post-acquisition), and caused a drop in employment levels.

Things I adapted include the cooking level and time for the glaze, using butter instead of margarine, and baking in two loaf pans instead of a tube pan, which of course altered the baking time.

I've made without altering and it is delicious but ofcourse I always take it to another level which is even YUMMIER!

Elections are run at the state level, so a state - gerrymandered election could alter that balance of power in the state legislature, which would effect things like voter - suppression measures, enactment and enforcement of campaign finance regulations, and the ability of elections to be monitored and for rules to be enforced by non-partisan (or partisan) entities.

Disruption of DENND5A function leads to altered levels of these receptors, which could explain why loss of DENND5A leads to the severe neurological developmental defects in the patients.

Modifying the vegetation cover alters the surface properties — such as the amount of heat dissipated by water evaporation and the level of radiation reflected back into space — which has a knock - on effect on local surface temperature.

They studied the bone metabolism at the cellular level using advanced imaging and computational techniques, which allowed them to identify 142 metabolites that were significantly altered by more than 1.5 times in the diabetic mice.

Studying surging glaciers could also offer insights into grander - scale ice flows with global consequences: the movements of the ice sheets in Antarctica and Greenland, which can change abruptly, altering the ice discharges that affect sea level.

During ice ages, which are mainly driven by rhythmic variations in Earth's orbit and spin that alter sunlight in the Northern Hemisphere, growing ice caps and glaciers trap so much frozen water on land that sea levels can drop a hundred meters or more.

He says that in these situations we set ourselves aspiration levels — which may alter over time — and stop looking only once these have been achieved.

Then although this rating can in principle be altered as a result of discussions by the study section, the level of modification which occurs in practice is quite minimal.

This is intriguing given that inflammation during pregnancy, which alters MHCI levels in the fetal brain, may slightly increase the risk of autism in genetically predisposed individuals, she said.

«MHCI levels are altered in the Alzheimer's brain, and altering MHCI levels in mice disrupts memory, reduces synapse number and causes neuronal insulin resistance, all of which are core features of Alzheimer's disease,» Boulanger said.

This published work could be used to alter glass geometry, levels of dissolved carbon dioxide, or even wine viscosity — which a consumer would not notice — to enhance bubble size, velocity and, thus, the «aroma experience,» he said.

In their paper entitled, «Malaria in pregnancy alters L - arginine bioavailability and placental vascular development,» Science Translational Medicine, 7 March 2018, Toronto General Research Institute (TGRI) and University of Toronto researchers report that Malawian women with malaria in pregnancy had altered levels of L - arginine which were associated with poor birth outcomes.

THE MEANING Since oxytocin increased the level of giving only in the first transaction — in which the partner's response mattered — Zak concludes that the hormone's effect is specific, altering generosity only when we have to think about others» feelings.

The team found that individuals with long - standing type 1 diabetes and diabetic enteropathy have altered colonic stem cells (CoSCs) and increased blood levels of a regulatory protein called insulin - like growth factor binding protein 3 (IGFBP3), which is produced in the liver.

Researchers at the Childhood Obesity Research Center at USC are looking at how maternal food intake affects fructose levels in breast milk as well as how specific elements in breast milk can alter a baby's developing gut bacteria, which neutralizes toxic byproducts of digestion.

Yet in addition to extinctions there are many dramatic, well - documented effects of introduced species, such as shifts in regional climate, reduced groundwater levels, altered nutrient cycling, and reduced oxygen levels in aquatic systems, which affect the abundance and distribution of native species.

However, the team was able to show that so - called tight junction proteins, which are known to be important for the blood - brain barrier permeability, did undergo structural changes and had altered levels of expression in the absence of bacteria.

«It was surprising to see all these significant changes in A1C and body weight without altering medications or activity level and without aiming for weight reduction,» Dr. Hamdy pointed out, «Which tells us that nutrition therapy can be as effective as medications even after a long duration of the disease.»

Research such as Alter et al.'s work points to the importance of becoming increasingly more specific about the situations and conditions that engage these distinct systems, which will prove to be essential in understanding how these multiple systems interact at a neural level.

For instance, this device can help us understand the mechanisms by which various inputs and treatments alter plant growth at the cellular level.

In combination with a separate technique that measures the degree to which a gene is expressed, the researchers then identified genes that were either mutated or functionally altered through expression levels in these bladder cancer cell lines.

The new evidence has the potential to alter perceptions about which planets in the universe could sustain life and may mean that humans are having an even greater impact on levels of CO2 in Earth's atmosphere than accepted evidence from climate history studies of ice cores suggests.

The extent to which physical and psychological symptoms are directly related to altered hormone levels remains speculative.»

Another question is for the noise - forcing mechanism, whether the high frequency forcing will change or whether the state at which the ocean becomes sensitive to such forcing will be altered (eg «charging» at a different rate or reaching «charged level» at a different threshold).

Fish exposed to higher carbon dioxide levels — which are expected to increase in the oceans for several decades — showed impaired cognitive function, learning difficulties, slowed visual capacity and altered sense of smell and sound.

These studies are unable to determine a causal relationship due to factors such as gene regulation — a genetic variant may instead contribute to altered expression levels of true causal genes, which remain undetected by a GWAS.

«The level of Lactobacilllus phage phiadh correlated with the prevalence of immunological disorders... which has been shown in animal models to alter the microbiome,» the Johns Hopkins study said.

The finding is based on studies of mice with altered levels of the growth factor PDGF in neural stem cells, which play a key role in the development of the eye.

Recent research was reported in an article in the Canadian Journal of Fisheries and Aquatic Sciences, which found that high levels of road salt can alter the sex ratios of frogs; an article in Environmental Toxicology and Chemistry, which documented the effects of road salt and a common insecticide on wetland food webs; and an article in Environmental Pollution, which examined potential interactions between road salt, predators, and competitors in wetland food webs.

Increased levels of atmospheric carbon dioxide could also significantly alter ocean temperatures and chemistry over the next century, which could lead to increased and more severe mass bleaching and other stressors on coral reefs.

It can also cause lower levels of thyroid hormone and testosterone, which can result in altered behavior, learning disabilities, or infertility.

In addition, the DHA and EPA found in fish oil have a powerful ability to enhance the metabolism and increase fat burning by positively altering the gene functioning through various mechanisms which include changing the makeup of cell membranes, altering the transcription of genes and influencing the levels of calcium within the cells.

For example, fluorides can cause zinc deficiency which in turn can cause damage to your brain by altering your manganese levels.

I would be shocked to see somebody with hair loss that had a healthy scalp pH so adding (quality) lactobacillus probiotics to your diet along with healing a leaky gut (many resources on the internet tell you how to do that) will not only alter skin pH to a healthy level but stop the chronic inflammation which, as is so rightly mentioned in this article, the catalyst for every disease / condition which we develop.

By maintaining estrogen levels within a normal range and altering the conversion ratio of estrogen into its 3 primary metabolites, Super DMZ 5.0 fosters an environment in which estrogen's benefits are maintained and its unwanted side effects minimized.

The new study found that prebiotic treatment alters the levels of brain - derived neurotrophic factor (BDNF), which is important for neuronal growth and survival; N - methyl - D - aspartate (NMDA) receptor subunits; and amino acids associated with signaling by the neurotransmitter glutamate, an excitatory neurotransmitter4, 12,13.

Many individuals with compromised detoxification capacity have an altered urinary pH level, which can negatively influence the kidneys» ability to eliminate toxins.

What is the mechanism by which a simple dietary change can alter the levels of this cancer promoter?

While the cause of SAD is still unknown, the disorder can alter melatonin levels, which play a role in your sleep / wake cycle, and cause daytime sleepiness and oversleeping.

Dr. Jason Fung explains how intermittent fasting drops your insulin levels, which alters your body's demand for insulin in a good way.

Bacteria - free mice exhibited higher levels of risk - taking, and neurochemical analysis revealed higher levels of the stress hormone cortisol and altered levels of the brain chemical BDNF, which has been implicated in human anxiety and depression.

There are still points where the film feels like it is moving from one level to the next, but this monotony is punctuated by a few scenes of story development, most of which center on a time - altering dagger.

The question is whether taking the test with extra time simply enables learning - disabled students to demonstrate their true level of knowledge and skills, which would presumably be reflected in their college GPAs, or whether it fundamentally alters the test.