Sentences with phrase «which cells increased»

Not exact matches

(She notes since introducing the mammogram, there has been a five-fold increase in Stage Zero breast cancer, a condition in which abnormal cells are found — but are not actively spreading — in the breast.)

Increased ability to burn fat: Research shows that cold - induced glucose uptake results in the creation of brown fat cells, which create warmth, burn energy and keep you slim.

In the study, mice were given food until they became obese, and were then fed the drug, which increases the cellular metabolism of obesity - linked white fat cells.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Tesla and solar cell manufacturing partner Panasonic currently have 14 jobs posted in the Buffalo area which is also expected to increase as the company aims for full production in 2019.

Cell biology is the same way — the cell itself may be highly organized, and order increased in comparison to the raw materials which make up the cell, but when you look at the total inputs and total outputs of all matter and energy, the overall entropy of the system increaCell biology is the same way — the cell itself may be highly organized, and order increased in comparison to the raw materials which make up the cell, but when you look at the total inputs and total outputs of all matter and energy, the overall entropy of the system increacell itself may be highly organized, and order increased in comparison to the raw materials which make up the cell, but when you look at the total inputs and total outputs of all matter and energy, the overall entropy of the system increacell, but when you look at the total inputs and total outputs of all matter and energy, the overall entropy of the system increases.

A human sex cell was imagined to contain a miniature homunculus, which increases in size until it becomes an embryo, an infant, and eventually an adult woman or man.

Far from being stultified by overcrowding, the cells of individual freedom, in a concerted action growing more powerful as they increase in numbers, will rectify and redress themselves when they begin to move in the direction towards which they are inwardly polarized.

The objects of his study range from a class of molecules that have the basic self - duplicating property of living things, through cells which suggest purely physical systems, through animals which give increasing evidence of having minds, to human beings in whom streams of consciousness seem to involve continual choices of action, at the opposite pole from control by impersonal laws of nature.

Brain O Brain capsules tackle stress and produce high level of energy, the herbs used in the preparation of these capsules contain iron in high amount which enhances the capacity oxygen carrying of the blood by increasing the number of red blood cells.

It also delivers higher levels of a special fat called conjugated linoleic acid, or CLA, which increases blood flow to the brain, extends the life of brain cells, and counteracts the effects of the stress hormone cortisol.

If fibrin excess can trigger unwanted inflammation in nerve tissue and increase breakdown of the myelin wrapping the nerve cells (a process that is usually referred to as demyelination), health problems like multiple sclerosis (in which there is breakdown of the myelin nerve sheath) may be lessened through reduction of excess fibrinogen and / or fibrin.

A 2012 study found that consuming maltodextrin increased bacterial adhesion to human intestinal epithelial cells and enhanced E. coli adhesion, which is associated with autoimmune disorders and dybiosis in your gut.

Increasing Metabolism and Digestive Efficiency Other research suggests that capsaicin causes the stomach's epithelial cells to secrete more gastric mucus, the glycoprotein which lubricates food masses and facilitates their movement throughout the stomach.

They are a rich source of vitamin C and flavonoids, which are powerful antioxidants, vitamin K that increases bone mass, potassium that helps electrolyte regulation, nerve function, muscle control, and blood pressure, folate that supports red blood cell formation and fiber.

Anabolic steroids work by helping the body's muscle cells produce more protein which, as long as the athletes works out, leads to increased muscle size and strength and, at the same time, also allows the body to produce more ATP, the «fuel» muscles need to move.

Your little one weighs almost 10 ounces, which is a major increase in weight since starting out as a single dividing cell, only 18 weeks ago.

With an allergic reaction, there is a release of mast cells, which contain heparin and histamine and then follows by an increase in IgE.

CITY Lips has a proprietary collagen peptide formula (using Celadrol ™ and Oligopeptide Technology *) that actually causes the cells in your lips to produce more collagen which in turn physically increasing the size of the lips.

Clamping the cord, especially at an early stage, may also cause the extra blood trapped within the placenta to be forced back through the placenta into the mothers blood supply with the third stage contractions.32 33 This feto - maternal haemorrhage (FMH) increases the chance of future blood group incompatibility problems, which occur when the current baby's blood enters the mother's blood stream, causing an immune reaction which can be reactivated in a subsequent pregnancy, destroying the baby's blood cells and causing anaemia or even death.

The Omega 3 fatty acids found in oily fish — such as salmon, trout, halibut, and tuna — help boost our immune systems, by increasing the activity of phagocytes, which are white blood cells that combat harmful bacteria.

Domperidone - A drug that has a side effect of increasing the hormone prolactin, which stimulates the cells in the mother's breast to produce milk.

Breast milk is a great way to improve and increase immunity in children, because it contains antibodies and white blood cells, both of which boost the immune system and help the body to fight against diseases.

However, the impact of the two methylation - regulating enzymes was still seen at 10 to 15 months, when scientists found decreased expression of hundreds of genes — many of which are key tumor suppressor genes such as BMP3, SFRP2 and GATA4 — in the smoke - exposed cells and a five - or - more-fold increase in the signaling of the KRAS oncogene that is known to be mutated in smoking - related lung cancers.

This study built on previous research from the Sundrud lab, which showed that when TH17 cells entered the intestine in human tissue samples, they increased the expression of a gene called MDR1.

«RyR2 is a mutation — we call it «leaky» RyR2 — that increases the normal amount of calcium inside the cell, which, in turn, triggers the release of an increased amount of neurotransmitters.

Between 10 days and three months, the cells exposed to smoke had a two - to four-fold increase in the amount of an enzyme called EZH2, which works to dampen the expression of genes.

After EZH2 enzymes rise, their levels taper off, and then, the scientists found two to three-fold increases in a protein called DNMT1, which maintains DNA methylation in the «start» location of a variety of tumor suppressor genes that normally suppress cell growth.

In the present study, the researchers have discovered a reason for reduced fertility in people with autoimmune polyendocrine syndrome type 1 (APS1), which increases the risk of developing autoimmune disease (caused by the immune system attacking and damaging healthy cells) and which is often used as a model for autoimmune disease in general.

The researchers also report that saliva increased DENV infection of immune cells in the skin and enhanced immune cell migration to neighboring lymph nodes, which could promote the spread of disease throughout the body.

In blood samples from these patients, the researchers found an increase in the percentage of gamma delta T cells, similar to what they observed in mice, which remained stable over years.

Beth Levine at the University of Texas in Dallas discovered that, in mice, autophagy — the process by which a cell recycles dispensable components for extra energy — increases 30 minutes into exercise.

Further investigations showed that the mutation causes reduced CTLA - 4 function, which led to increased infiltration of the intestinal mucosa by T - cells and therefore to chronic diarrhea.

The latest findings show that genetic defects in the body's ability to manufacture carnitine might be associated with an increased risk of autism because carnitine deficiency interferes with the normal processes by which neural stem cells promote and organize embryonic and fetal brain development.

Fostamatinib's effect on microtubules seems to increase the stabilizing effect of paclitaxel, even in resistant cells, which in turn may prevent cancer cells from proliferating, says Yu Yu, Ph.D., a postdoctoral fellow at the Johns Hopkins University School of Medicine and co-author of the study.

In addition, compared to mice on a regular diet, brain cells from animals in the olive oil group showed a dramatic increase in nerve cell autophagy activation, which was ultimately responsible for the reduction in levels of amyloid plaques and phosphorylated tau.

Dr. Llovet and colleagues demonstrated that the expression of mutant IDH in the adult liver of genetically engineered mice impairs liver cell development and liver regeneration — a process in which the liver responds to injury — and increases the number of cells to form a tumor.

Calorie restriction slowed the glycolytic rate in the muscles and increased the cells» dependency for OXPHOS versus glycolysis in older rats, which was linked to improvement of normalized muscle mass.

«What we think happens is that the bacteria activate immune cells, which release chemicals called cytokines that then act on receptors on the sensory nerves to increase their activity,» he says.

However, along with this seemingly linear storyline in which retinoids block progesterone's promotion of CK5 + cells, previous work in the lab of CU Cancer Center investigator Peter Kabos, MD, and others shows that breast cancers treated with anti-estrogen drugs like tamoxifen or aromatase inhibitors show an increased population of CK5 + cells — it is as if these therapies remove the roadblock of estrogen - dependent cells, leaving CK5 + cells to proliferate.

Meanwhile, recent human studies indicate that aging is associated with an increase in somatic mutations in the hematopoietic system, which gives rise to blood cells; these mutations provide a competitive growth advantage to the mutant hematopoietic cells, allowing for their clonal expansion — a process that has been shown to be associated with a greater incidence of atherosclerosis, though specifically how remains unclear.

The diet increased the levels of leptin — a hormone produced by fat cells that usually signals satiety in the brain — in the bone marrow, which promoted the development of fat cells instead of bone cells.

In our study, as BMI increased, we started seeing an increase in the ability of multiple myeloma cells to adhere, which causes the cancer to better anchor,» DeCicco - Skinner explained.

Finally, the team grew the tissue in a three - dimensional system, which coaxed it into forming all the structures found in gut tissue, including the finger - like villi that protrude inwards to increase surface area, and recesses called crypts containing the intestinal stem cells that renew the gut lining weekly (Nature, DOI: 10.1038 / nature09691).

Kasper says that these results suggested a pathway: without exposure to certain microbes, methylation increases CXCL16 expression, which ultimately increases iNKT cell numbers and inflammation.

In the study, exosomes, which are generated by all cells and are naturally present in blood, were modified as «iExosomes,» capable of delivering small RNA to specifically target mutant KRAS, resulting in disease suppression and increased overall survival in mouse models.

Roughly 2 % of people over age 35 have chronic glaucoma, in which fluid builds up inside the eyeball, leading to increased pressure and eventual death of cells in the optic nerve.

«The increased number of exosomes reaching the pancreas may gain further advantage to enter KRAS - associated cancer cells as a result of enhanced macropinocytosis, which concurs with previous findings,» said Kamerkar.

Researchers at Georgetown University Medical Center recently discovered that these drugs also interact with specific proteins on the surfaces of nerve cells — which could also lead to increased pain when patients wake up.

These include a plant - produced chemical called resveratrol, which spurs cells to increase production of sirtuins, the proteins that promote cell survival.