Sentences with phrase «which cellular senescence»
However, there is a scenario in which cellular senescence is desirable.
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Intermittent dosing with rapamycin selectively breaks the cascade of inflammatory events that follow cellular senescence, a phenomena in which cells cease to divide in response to DNA damaging agents, including many chemotherapies.
Pulmonary fibrosis can possibly be attributed to a kind of cellular aging process, which is called senescence.
They include reduced lymphocyte repertoire, increasing clonality and increasing autoreactivity.5, 7,8 Recent work has focused on intrinsic cell defects, which alter T cell activation threshold, induction of cellular senescence and differentiation into short - lived effector or long - lived memory cells.
Proteasome activation is required for palbociclib ‐ induced cellular senescence, which is sensitive to the proteasome inhibitor bortezomib.
For his 2013 SENS Research Foundation Summer Internship, Ethan joined the laboratory of Dr. Judith Campisi at the Buck Institute for Research on Aging to study cellular senescence, the process by which damaged cells enter irreversible growth arrest.
It has recently been proposed that the primary role of cellular senescence is in mitotic compartments of fixed size in which spatial considerations dictate that a deleted cell is replaced by a neighboring cell.
This review therefore brings together and discusses recent findings which suggest that cellular senescence does contribute to ageing and the development / progression of disease.
When this occurs, a cell enters into a state of growth arrest known as «cellular senescence,» which is the cellular equivalent of aging.