Sentences with phrase «which decreases growth»

This shift between catabolism and anabolism is thrown off when circadian rhythm is thrown off, resulting in decreased prolactin, which decreases growth hormone, which decreases autophagy (source).

Not exact matches

Tom Wynn, director of affluent research at Spectrem, provided several factors for the increased confidence: the steady improvement in job growth, the steady increase in the major stock market indices since the spring, and a decrease in political ambiguity with the election season over, which has an effect on at least some people's outlook.

Growth from CenturyLink's broadband, hosting, and TV customers wasn't enough to outweigh decreased income from higher - margin legacy services, which led the Louisiana - based telecom to swing to a full - year loss from a 2012 profit.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Today, there are fewer than half as many, which is a reflection both of teenagers» decreasing work force participation and of the explosive growth in restaurants.

As you can see, our gross profit dollar growth was down $ 140 million or 2.7 %, which was in line with our expectations, while SG&A dollar growth decreased by $ 62 million or 1.6 %, reflecting outstanding SG&A control during the quarter.

To better understand our prescription trends, we have isolated the impacts of Express Scripts day fall and cough / cold / flu, adding back the 10.7 % negative impact we experienced from exiting the Express Scripts network, to reconcile to an adjusted 1.6 % prescription growth rate, which compares favorably to the industry, including Walgreens, which decreased at 0.3 % over the same period per IMS.

This was primarily due to accelerated repayments of contributions by Pratt & Whitney Canada In 2015 - 16, which decreased transfers in that year, along with the impact of measures contained in Budget 2016 to foster economic growth.

A flattening yield curve, in which the gap between short - term and long - term rates is decreasing, can be a sign that the economy is slowing down — or that policymakers are trying to put the brakes on growth.

There was a marked decrease in programming which was broadcast on sustaining - time, and a corresponding growth in both the number and size of the independently syndicated evangelical programs which were broadcast on purchased time.

Furthermore, if investment rates in the U.S. fall (as a result of decreases in investment by foreigners and rising budget deficits), the result will be slower growth in American productivity, which jeopardizes both near - term and long - distant future earnings.

Certainly there has been a marked growth in the amount of syndicated religious programming, but there has also been a corresponding decrease in other types of religious programming which previously filled a substantial block in station schedules.

Compound annual growth rate remains steady at 5.4 % over a 10 - year period SEATTLE (March 1, 2018)-- Washington State's wine grape harvest totaled 227,000 tons in 2017, which equated to a 16 - percent decrease compared to the record - breaking 2016 harvest of 270,000 tons.

They are a good source of potassium, which may decrease the growth and development of blood vessel plaques and is also good for lowering high blood pressure.

This recipe is full of chickpeas which help promote bone health, improve blood sugar levels in diabetics, improve blood pressure, promote heart health, reduce bad cholesterol, and reduce risks of cancer and decreases tumor growth rates.

Researches suggest that the intake of almond milk decreases the growth of prostate cancer cells which are stimulated by regular milk.

Third, when babies experience growth spurts they typically increase their milk intake which can correlate to a decrease in expression output when pumping after feeding.

Your baby may drink more during growth spurts or less when she starts solids, which will decrease or increase your pumping output.

The report draws on government and trade statistics, academic evidence and economic theory to challenge arguments that the health and social benefits of reducing alcohol consumption are likely to come at a cost to the economy, finding: · Any reduction in employment and income resulting from lower spending on alcohol would be offset by spending on other goods · Econometric analysis of US states suggests that a 10 % decrease in alcohol consumption is associated with a 0.4 % increase in per capita income growth · Lower alcohol consumption could also reduce the economic costs of impaired workplace productivity, alcohol - related sickness, unemployment and premature death, which are estimated to cost the UK # 8 - 11 billion a year The analysis comes at a timely moment, with health groups urging the Chancellor to raise alcohol duty in next month's Budget.

While state Comptroller Thomas DiNapoli's report tied Albany's $ 1,952,777 decrease to competition from retail store growth in surrounding counties, Albany County Comptroller Mike Conners and other county officials said more people purchasing items online — which sometimes aren't locally taxed — contributed to the decline.

These long - lived worms had mutations that decreased the production of a protein known as insulinlike growth factor 1 (IGF - 1), which helps drive cellular growth and division.

Following fire, managers sometimes thin recovering forests, which can encourage growth of large trees and can even decrease the susceptibility of particular stands to beetle attacks.

The importance of stromal POSTN was also demonstrated in another study in which orthotopic inoculation of gastric cancer cells into Rag2 − / −; Postn − / − mice reduced tumor size, decreased invasiveness, and decreased growth compared to Rag2 − / −; Postn + / + mice (Kikuchi et al., 2014).

During these stages, growth hormones and melatonin levels (which are important for muscle maintenance and repair) increase, while the stress hormone cortisol decreases.

Your fat tissue contains the most abundant source of mesenchymal stem cells (MSCs) in your body — a class of repair cells which have the ability to decrease inflammation, repair or replace damaged tissue while stimulating new blood vessel growth for improved blood flow.

This innovative treatment utilizes adult stem cells (from your body fat) which have the ability to decrease inflammation, repair damaged tissue, facilitate better cell - to - cell communication and stimulate new blood vessel growth for better blood flow to the affected area (s).

Studies show that consuming sugary foods decreases your immunity and increases insulin - like growth factor, which is a promoter of colon, breast, and prostate cancers.

Cortisol, on the other hand, breaks down muscle tissue and increases fat storage, which means increasing cortisol and decreasing testosterone is the least desirable situation when it comes to achieving muscle growth and burning fat.

Creatine's ability to increase muscular hypertrophy is derived largely from the fact that it is able to trigger creation of new muscle cells, increase protein synthesis in the muscles and decrease the production of myostatin which depletes muscle tissue, while at the same time increase the release of particular hormones that promote muscle building like IGF - 1 (Insulin Growth - like Factor) and testosterone.

Researchers have found that oral carnitine increases energy, decreases fat mass, and supports muscle growth, which may lead to weight loss in active individuals.

Sclerostin is a protein produced by bone cells which has a negative impact on the formation of bone when expressed at high levels by decreasing bone formation, and IGF - 1 is a hormone associated with the growth of bone.

This type of dieting has been put to the test hundreds of times and has been shown repeatedly to decrease insulin levels, which in turn helps with weight loss; increase the amount of HGH (Human Growth Hormone) and even repair cells and help with their recovery.

The chronically stressed mice had decreased immune function and experienced tumor development significantly earlier than the non-stressed mice.16 Other mouse studies of ovarian cancer showed that chronic stress resulted in increased cancer growth as well as increased angiogenesis, the process with which cancer forms new blood vessels to feed itself nutrients for growth and metastases.17 Chronic stress has also been shown to decrease our body's ability to mount an attack against foreign invaders, including viruses.18 As we know that several viruses can cause cancer (HPV and cervical cancer, and EBV and nasopharyngeal cancer), we can extrapolate that any decrease in immune function could increase cancer risk.

Shrinkage and decreased functions affect the liver, kidneys, and other organs unless the body can maintain a proper ratio of growth hormone which protects them through restorative cellular regeneration.

Reducing IGF - 1 levels has a direct on decreasing insulin which may reduce tumor growth and cancer over time by following a ketogenic diet.

Goji causes the body to produce growth hormone (which decreases with age) and that's why is believed to be anti aging.

It's also worth mentioning that eating a low - carb diet will decrease your strength and muscle endurance, which makes it harder to progressively overload your muscles in the gym and thereby maximally stimulate muscle growth.

This mineral has been known to reduce inflammation, decrease tumor growth, and has the ability to stimulate the production of killer T - cells — which improves immune function in response to infections.

Adding turmeric to your daily nutrition decreases the risk of developing cancer, because curcumin not only reduces inflammation, but also reduces free radical damage to DNA and inhibits the growth of cancer cells, especially those of the colon, which regenerate at every three days.

By shocking your body, you'll attain muscle growth, which would decrease the percentage of your body fat.

In addition, insulin also decreases muscle breakdown, which further enhances muscle growth.

This means that insulin decreases the rate at which muscle proteins are broken down, which creates a more anabolic environment conducive to muscle growth.

Significant drop in PSA levels (which is a biomarker of prostate cell growth); a drop in cholesterol (which is what we'd expect with a lower - fat diet, and all that extra fiber); and, importantly, a significant decrease in the cellular proliferation rate.

It also contributes to bone density, and increased and steady intake can decrease risk of fractures which is very important for adolescents undergoing rapid growth, post-menopausal woman, and the elderly.

Consequently, the normal rate of cell proliferation would have been decreased during protein deprivation, which is similar to the retardation of brain cell growth of young malnourished animals described by Winick and Rosso (18).

«the normal rate of cell proliferation would have been decreased during protein deprivation, which is similar to the retardation of brain cell growth of young malnourished animals.

«[T] he normal rate of cell proliferation would have been decreased during protein deprivation, which is similar to the retardation of brain cell growth of young malnourished animals.

In addition, insulin decreases Sex Hormone Binding Globulin (SHBG) which increases the amount of free testosterone in the blood which increases the masculinizing symptoms (hair growth etc.) seen in PCOS.

A drop in the amount of folic acid in your body is capable of decreasing cell division and growth of hair follicle cells, which, in turns leads to your hair growing less.

Probiotics have been shown to decrease cortisol and may help keep testosterone levels higher, which can increase workout performance, enhance muscle growth, while increasing fat loss.