Sentences with phrase «which decreases the ability»

«I see twisted harness straps all the time, which decreases their ability to hold your child securely in a crash,» says Dr. Hoffman.

Accredited practising dietitian and spokesperson for the Dietitian's Association of Australia, Sonya Stanley, says in her experience picky eaters tend to avoid fruit and vegetables — or eat a very limited range — which decreases their ability to achieve a balanced and healthy diet.

«If we're consuming carbohydrates at a faster rate than our bodies are utilizing them for energy, that extra glucose gets stored in the fat cells of the liver, which decreases its ability to break down excess estrogen and allowing it to hang around in our systems longer than it should.

When you're sedentary for an extended length of time, your core begins to weaken, which decreases your ability to move efficiently.

These dogs often have small tracheas and long soft palates, which decrease their ability to cool themselves.

Not exact matches

Anything less than this is considered to be inadequate, which can limit your motivation, increase the release of cortisol (a stress hormone), as well as decrease your body's ability to recover from exercise — all of which are damaging to your health and fitness routine.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

These risks include, in no particular order, the following: the trends toward more high - definition, on - demand and anytime, anywhere video will not continue to develop at its current pace or will expire; the possibility that our products will not generate sales that are commensurate with our expectations or that our cost of revenue or operating expenses may exceed our expectations; the mix of products and services sold in various geographies and the effect it has on gross margins; delays or decreases in capital spending in the cable, satellite, telco, broadcast and media industries; customer concentration and consolidation; the impact of general economic conditions on our sales and operations; our ability to develop new and enhanced products in a timely manner and market acceptance of our new or existing products; losses of one or more key customers; risks associated with our international operations; exchange rate fluctuations of the currencies in which we conduct business; risks associated with our CableOS ™ and VOS ™ product solutions; dependence on market acceptance of various types of broadband services, on the adoption of new broadband technologies and on broadband industry trends; inventory management; the lack of timely availability of parts or raw materials necessary to produce our products; the impact of increases in the prices of raw materials and oil; the effect of competition, on both revenue and gross margins; difficulties associated with rapid technological changes in our markets; risks associated with unpredictable sales cycles; our dependence on contract manufacturers and sole or limited source suppliers; and the effect on our business of natural disasters.

The results are consistent with a simple experience good model where biomedical misconceptions decrease consumers» ability to infer quality, which retailers exploit by selling lower quality medicines.»

Examples of these risks, uncertainties and other factors include, but are not limited to the impact of: adverse general economic and related factors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commission.

JED has been described as «an ecumenical sharing of abilities and expertise» and a partnership which makes «good, economic sense in these days of decreasing financial resources for the work of the church.»

Children that don't get the nutrients their bodies need will often have decreased cognitive abilities and performance in the classroom.These children are also at a higher risk for disease, which means they will miss classes.

Furthermore, it is now clear that all kinds of crying (i.e. fussing, crying and inconsolable crying) is prolonged, that this prolongation occurs only in the first few months, and that inconsolable crying is almost unique to the first few months of life.3, 40 The «unpredictability» of the crying, and of the caregiver's ability or inability to soothe the infant is most likely due to the facts that (1) the infant cry in the first few months is a reflection of the organization of its behavioural states (crying, awake alert, sleeping), rather than an intentional «signal,» 14 (2) that behavioural state changes occur in «steps» rather than due to increases or decreases in arousal7, 41 and (3) infants are resistant to behavioural state change unless they are in a transitional phase in which they are «ready» to change state.7 Finally, there is now good evidence that the proportion of infants that have evidence of organic disease to explain their crying is less than 5 %.8, 42,43 In the absence of other compromise, infants with «colic» have as good an outcome as infants without «colic.»

The approach halts further necrosis and can save a baby's life, but it often leaves infants with insufficient intestine and puts them at risk for long - term complications, such as short bowel syndrome, which requires feeding support for life due to the intestines» decreased ability to absorb enough nutrients.

Babies who can roll themselves over are at a significantly decreased risk of SIDS, which experts believe is because babies with that ability have also developed the maturity to sense trouble during sleep and move into a safer position.

The aforementioned Parents article noted that lack of sleep decreases people's ability to think clearly, which is especially dangerous for new parents.

The findings could have an impact on the tests and measurements that physicians rely on to diagnose and treat two heart conditions: hypertrophic cardiomyopathy, in which the heart muscle becomes abnormally thick, and non-ischemic dilated cardiomyopathy, in which the heart's ability to pump blood decreases as the organ's main pumping chamber, the left ventricle, is enlarged and its muscle thinned.

Studies document decreased reaction times, worsened managerial skills, less ability to concentrate, and an increased risk for injury even when alcohol can no longer be detected in the blood... all of which add up to major economic consequences.

BRAF mutations, which occur in about 40 to 50 percent of these patients, have been associated with aggressive tumors and decreased ability of tumors to respond to radioactive iodine, typically the first line of treatment in these patients.

Guessing that the reduced ability to control force in patients with PD was related to decreased dopamine — which makes it harder to «recruit» neurons for a particular task — the researchers devised a brain stimulation experiment to further test their hypothesis.

MCI, which is thought to be a preliminary stage of Alzheimer's, is a state in which cognitive functions, such as memory or thinking ability, decrease at a level that do not affect daily life.

Hensley and his team reported this egg - induced mutation, which was present in the 2016 — 17 U.S. seasonal flu vaccine, decreases the ability of certain antibodies to attach to and destroy the flu virus — by a whopping three orders of magnitude.

This can lead to obesity, high blood pressure and a decreased ability to process sugar — the combination of which is known as the «metabolic syndrome.»

Your fat tissue contains the most abundant source of mesenchymal stem cells (MSCs) in your body — a class of repair cells which have the ability to decrease inflammation, repair or replace damaged tissue while stimulating new blood vessel growth for improved blood flow.

This innovative treatment utilizes adult stem cells (from your body fat) which have the ability to decrease inflammation, repair damaged tissue, facilitate better cell - to - cell communication and stimulate new blood vessel growth for better blood flow to the affected area (s).

Research has found that 60 percent of those with chronic migraines have genetic changes that decrease their body's ability to metabolize magnesium, which relaxes blood vessels in the brain.

Meals rich in protein have the ability to stimulate your liver and delay the emptying of your bowels, thus decreasing the rate at which it enters the bloodstream to 40 %.

Creatine's ability to increase muscular hypertrophy is derived largely from the fact that it is able to trigger creation of new muscle cells, increase protein synthesis in the muscles and decrease the production of myostatin which depletes muscle tissue, while at the same time increase the release of particular hormones that promote muscle building like IGF - 1 (Insulin Growth - like Factor) and testosterone.

So getting stressed about your expected results and how fast they're going to happen can also cause our stress hormones to rise, which in turn promotes storage of more belly fat, decreases our ability to get good rest and decreases quality of life and life enjoyment.

The chronically stressed mice had decreased immune function and experienced tumor development significantly earlier than the non-stressed mice.16 Other mouse studies of ovarian cancer showed that chronic stress resulted in increased cancer growth as well as increased angiogenesis, the process with which cancer forms new blood vessels to feed itself nutrients for growth and metastases.17 Chronic stress has also been shown to decrease our body's ability to mount an attack against foreign invaders, including viruses.18 As we know that several viruses can cause cancer (HPV and cervical cancer, and EBV and nasopharyngeal cancer), we can extrapolate that any decrease in immune function could increase cancer risk.

It produces a hormone that's gonna cause fats — it's gonna basically produce leptin which is another hormone that's gonna decrease our body's ability to signal satiation and signal that we're full, which is another thing, and it's also gonna produce more sex hormones like estrogen.

Because it decreases the body's ability to absorb and process so many essentials, the consumption of soy also leads to an increased need of Vitamin B - 12, Vitamin D, magnesium, and calcium, which are already difficult enough to consume adequately in our modern diets.

Your ability to focus and your reflexes are impaired, which can lead to accidents and decreased productivity.

Once the fatty acids begin to spill over into your organs, like the heart, liver, and kidneys, the organs ability to perform diminishes which raises blood pressure, decreases metabolism, and weakens the body's immune system.

This mineral has been known to reduce inflammation, decrease tumor growth, and has the ability to stimulate the production of killer T - cells — which improves immune function in response to infections.

This constant abuse decreases the body's ability to produce HCI which leads to incomplete digestion, poor absorption and vulnerability to infection.

Signs that there is a vitamin deficiency may include gingivitis, which is characterized by an inflammation and bleeding gums; dry skin; dry and splitting hair; easy bruising; a decreased ability to ward off infection, nosebleeds; and decreased rate of healing for wounds.

Individuals with celiac disease can have decreased activity of the enzyme sucrase and thus a decreased ability to digest sucrose [13], which may contribute to abdominal bloating and diarrhea.

Unfortunately, aging cells have a diminished ability to produce ATP due to changes in mitochondrial structure and function — unless we intervene or support our cellular energy production.Research indicates that mitochondrial DNA mutations begin accumulating in individuals starting in their mid-thirties which contributes to the decreased energy that so many people experience with increasing age.

If you continue to train with dysfunctional movement (i.e. weakness, imbalances, mobility issues, etc.), you will be training in a dysfunctional manner, which will put you at risk for injury and decrease your ability to workout to you highest potential.

Much less water would flow, which in turn would decrease the ability of the hose to squirt out the marbles.

In chronic Lyme and associated diseases Ashwagandha is an herbal medicine adaptogen, a substance which improves the ability to withstand stress, that improves energy and stamina, stimulates white blood cells to fight infection, balances adrenal and thyroid gland function, decreases inflammation, and decreases anxiety.

Other studies have found that NSAID use during long events, such as a marathon or triathlon, actually decreases kidney function, which can lead to very dangerous issues during exercise, including a decreased ability to properly regulate your sodium and electrolyte status and your hydration levels (27).

Two approaches may be taken — you can try to increase the body's ability to detoxify itself, or you can try to decrease the toxic load to which you subject the system.

Chromium picolinate which decreases the bodies fat storing abilities thereby reducing the amount of fat lipids that are stored around the pectoral muscles.

Like the actual gas pedal in a car, analog triggers offer the ability to gradually increase and decrease acceleration, which is critical in realistic racing titles.

Furthermore, extremes of heat and cold decrease battery lifespan — using a medium which determines the location of all devices is a sensible way of controlling the stored environment, particular with the ability to move trolleys around as winter approaches to the best temperature - regulated areas of the building.

The percentage of boys who felt reading was hard decreased from 28 per cent down to 15.9 per cent, which the NTL suggests shows increased confidence in their reading ability.

One of the main benefits of steer - by - wire is the system's ability to decrease the amount of feedback and vibration felt in the steering wheel, which is especially nice on rough roads.

Negative information on your credit reports decrease your credit score, which can have a negative impact on your ability to get a credit card, home financing or even a job.