For example, although Cooper's team successfully read methylation from a fossil bison specimen, they could not find a
signal in five other bison fossils they examined,
which suggests that reading ancient
epigenetic signatures requires exceptional preservation.
For instance, a congenital disorder called Beckwith - Wiedemann syndrome involves the malfunctioning of a gene encoding a
signalling molecule called IGF2,
which encourages fetal growth (see «
Epigenetics: Discovery «-RRB-.