Sentences with phrase «which food antigens»

pTreg cells were also believed to exist in the small intestine to inform the immune system on which food antigens can enter our body.

Not exact matches

Deletion of the GM - CSF gene in the mouse led to reduction and impaired regulatory function of gut tissue macrophages and dendritic cells which compromised induction of tolerance to food antigens and increased mice susceptibility to IBD.

During exposure to food antigens or nonpathogenic microbes, inflammation is absent, which results in immune tolerance — the default response.

For instance, a decrease in bifidobacteria populations leads to intestinal hyper - permeability, or leaky gut, which in turn leads to the translocation of metabolic byproducts, food antigens, bacteria, and lipopolysaccharide (also known as LPS, an immunogenic cell wall component from Gram - negative bacteria) across the gut barrier into systemic circulation (Rapin & Wiernsperger, 2010).

However, a Westernized diet high in fat and sugar has also been shown to cause a more porous intestinal lining, the consequences of which include systemic access to food antigens, environmental toxins, and structural components of microbes, such as lipopolysaccharide endotoxin (LPS)[60].

Leaky gut is a condition in which undigested food proteins leak through an inflamed and overly permeable intestinal barrier, triggering an antigen attack and contributing to food sensitivities.