Sentences with phrase «which gene sets»

Not exact matches

Instead of just focusing on human DNA, which in the other studies had yielded limited results, she looked at multiple sets of genes — and not just from humans.

The death penalty should be abolished not for religious reasons (also religious people seem to approve of the dath penalty — which to me makes no sense) but because every person who is killed is one less set of DNA to be passed on to succeeding generations, and who knows what those wasted genes could mean for the future of the species?

But it is not actually the crucial question, which is, What controls the activity of the complex interacting set of genes, which produces a nerve cell or a muscle cell?

The shared patterns of gene expression in the limbs and phallus are generated in part by a common set of noncoding DNA, also called «elements» or «enhancers,» which act to control gene expression in both of these structures, argues a study published October 1 in Developmental Cell.

However, there is certainly a ceiling set by our genes, which define our maximum potential for growth,» Stock says.

A transcriptome is the set of all RNA molecules transcribed in each cell type, and a readout on which genes are turned in that cell at the time.

Next, Anderson and his colleagues used a set of genetic tools to identify exactly which neurons were responsible for the effect on aggression and to see if the gene that encodes for Tk also controls aggressive behavior by acting in that cell.

The team then compared how similar gut bacteria were in identical twins (which have the same set of genes) and non-identical twins (who are assumed to share a very similar environment, but do not have exactly the same genes).

While the vast majority of our genes are housed in the nucleus, the cytoplasm contains tiny energy - producing structures called mitochondria, which have their own set of 13 genes.

As she set out to design her research, she noticed that many genes being identified were linked to high BMI, which simply compares someone's weight with their height.

«But what is interesting within cichlids, which is this group of very diverse fishes, is that they can express different sets of these seven genes.

The plant is therefore polyploid, which means it has a four-fold set of chromosomes and almost twice as many genes as its original species.

The study identifies a wide set of genes — previously associated with complex structures in higher animals — which were supposedly absent in sponges.

«We captured about 95 percent of the gene targets we set out to capture, many of which were very large in DNA length, which has been challenging in the past,» Parekkadan said.

In addition, the team also uncovered that ZBTB48 can activate the production of a specific set of genes, which include a mitochondrial gene called MFTP1.

Johns Hopkins researchers say they have identified a set of genes that appear to predict which tumors can evade detection by the body's immune system, a step that may enable them to eventually target only the patients most likely to respond best to a new class of treatment.

Females are diploid, which means that they have two complementary versions of sex - determining genes, one set inherited from the mother and another from the father.

Using genetic probes, Weeks showed that each chromosome carries different genes, which means they are a haploid set.

First author Professor Martin Hrabe de Angelis, Director of Institute of Experimental Genetics at the Helmholtz Zentrum München, who invented the mouse clinic concept, said: «Our findings with regard to the genes examined are now available to the scientific community as a valid data set, which can be downloaded free of charge from the IMPC (International Mouse Phenotyping Consortium) website, and form an excellent basis on which we and other research groups can develop and test new hypotheses.»

But bring this gene to a modern setting — with couch lounging and salty snacking — and it is easy to retain more salt than is needed, which can lead to medical problems like high blood pressure.

«We set out to find which genes can regulate the cells that initiate brain metastases, which we've termed brain metastasis initiating cells or BMICs.

It's a mystery how the status of our immunity genes shows up in our armpits, but the researcher who discovered the phenomenon, Claus Wedekind of the University of Berne, Switzerland, speculated that potential partners use the signal to assure that their children get a varied set of immunity genes, which may help them ward off diseases better.

Curious about the possibility of circular RNAs contributing to cancer, Pandolfi and his colleagues set out to see if they could detect relevant changes in tumors known to harbor distinct fusion proteins, which result when different chromosomes abnormally join together, melding two separate genes into a new centaur - like gene.

Mitochondria, which can exist by the scores in a eukaryotic cell, have their own set of genes, which can replicate and mutate faster than the cell's better - known complement in the nucleus.

Eventually I went to the University of Michigan and set up a lab which was involved in trying to find genes that were the cause of various frustrating human diseases.

One person takes a drug and has a set of side effects, all of which could involve different genes.

The researchers set out to find the genes responsible for this growth defect and after years of work, they were able to discover the underlying gene, which they refer to as ICARUS1, reflecting the temperature sensitivity conferred by the gene.

Most well known is the increased risk of certain chromosomal abnormalities such as Down's syndrome, in which there is an extra set of genes in each cell.

The team first set out to determine which RBPs were critical in RNA - mediated gene regulation by applying an RNAi screen to mESCs.

Sometime in the past 1,500 to 20,000 years, Y. pestis lost a set of genes for proteins called adhesins, which bind the bacteria to intestinal walls.

Dangl intends to greatly expand his efforts to understand which plant genes are involved in setting up microbe communities associated with roots.

«BinoX works so well thanks to the high density of the FunCoup networks, which makes it possible to find many functional network links between gene sets, even if they have no shared genes.

In the lycopene experiment, Church did not know which modifications to make in the E. coli genes to get the result he wanted, but the technique could just as easily be used to introduce specific sets of changes into a genome, inserting and deleting hundreds or thousands of genes at once.

The discovery sets the stage for splicing the full suite of genes needed to produce morphine from yeast, which would produce safer and cheaper drugs — or allow drug deals to brew opiates.

To make BinoX directly usable for other researchers, a public web server http://PathwaX.sbc.su.se (Ogris et al., 2016b) was set up for on - line pathway analysis of single gene sets, which applies the BinoX algorithm to all KEGG pathways and FunCoup networks.

The paper demonstrates how BinoX can be used to find many biologically meaningful pathway annotations for gene sets from cancer and other diseases, which are not found by other methods.

They built a set of synthetic genes that function in cells like NOR gates, commonly used in electronics, which each take two inputs and only pass on a positive signal if both inputs are negative.

And so they have long sought haploid embryonic stem cells, which can become any kind of tissue but contain just one set of genes, like a sperm or egg.

Surprisingly, these conserved gene sets were also associated with several other biological traits, which evolved multiple times in ants, such as number of queens in a colony, whether an ant species is invasive or not, and the degree of worker sterility.

All these cells were isogenic, which means they all had the same gene set.

The diseases in question affect mitochondria, which are cellular energy producers that carry their own set of genes.

The tomato aficionado might conclude that, given the immense varieties — which go by such fanciful names as Aunt Gertie's Gold and the Green Zebra — heirlooms must have a more diverse and superior set of genes than their grocery store cousins, those run - of - the - mill hybrid varieties such as beefsteak, cherry and plum.

Researchers observed that the set of genes involved in memory consolidation coincided with the genes regulating Crtc1, a protein which also controls genes related to the metabolism of glucose and to cancer.

Its most common iteration, CMT1, comes in many forms, most of which have to date been linked to a small set of causative genes.

We have long known that autism itself is genetic, but by combining these different data sets (brain imaging and genetics) we can now identify more precisely which genes are linked to how the autistic brain may differ.

One of the gene's molecular targets, for example, is a microRNA (a small noncoding RNA molecule) called let7, which in turn regulates hundreds of other genes, so the effects of Lin28a can set off a complex array of regulatory interactions.

Deepak Srivastava, MD, leads the Center, which was set up to honor Star Trek creator Gene Roddenberry.

Dluzen et al. demonstrate that differential expression of a set of miRNAs correlate with expression of a larger set of target genes in pathways which are relevant to disease pathogenesis and are differentially expressed between patients of different genetic background.

The researchers suggest that since the adult muscle stem cells are only activated when injury occurs (by trauma or exercise), they use a new set of genes from those used during embryonic development, which proceeds without injury.

These genes will be incorporated in new gene sets, which will be tested and validated.