From such combined restoration - research experiments, scientists can learn
which genetic lines are most likely to survive future climates.
Not exact matches
This has to do with the closer link between the mother and her offspring, a fact
which humans share with all mammals: the perpetuation of the
genetic line is more dependent on the females» constant care and attention than upon the males».
Where is the clear
line in a progression from (1) using animal insulin to treat diabetes, to (2) using gene remodeling techniques to grow insulin in a host bacterium that will reproduce rapidly and from
which a plentiful supply of insulin can be harvested, to (3)
genetic surgery to replace the defective gene in a person diagnosed as diabetic, to (4)
genetic surgery immediately after fertilization in order to replace the defective gene and alter the germ cells
which would otherwise have transmitted the disease to one's offspring?
Burke, whose lab studies the genomic basis of evolutionary divergence within the sunflower family, was involved in the
genetic mapping upon
which the genome assembly was based and oversaw the whole genome re-sequencing of the 80 sunflower
lines described in the paper.
In experiments with cancer cell
lines, the PIM1 inhibitors killed cells in a MYC - dependent manner, and in two different mouse models — one in
which mice were implanted with patient tumors and the other in
which a
genetic alteration of MYC predisposes the mice to tumor development — the administration of PIM1 inhibitors resulted in significant tumor regression.
Half of the mice studied, belonging to a
genetic line that suffers a form of Crohn's disease were more affected than the remaining half of mice,
which belong to a healthy mouse
line.
Using
genetic analyses, the researchers showed that a commonly used cell
line which was established in Uppsala, Sweden, almost fifty years ago does not originate from the patient it is claimed to stem from.
Then, the team used
genetic analysis to look at mitochondrial DNA,
which can pass only along the maternal
line.
To see if any of these lay in
genetic sequences on
which the p53 protein acts, the investigators used data from several
lines of healthy and cancerous cells subjected to various p53 - activating treatments.
Great Britain's Human Fertilisation and Embryology Authority (HFEA),
which oversees fertility treatments and embryo research in that nation, recently approved fertility procedures that would amount to the
genetic engineering of children through cloning (nuclear transfer) technology and germ -
line modification, resulting in a «three - parent embryo» that would have
genetic material from two mothers and one father.
The DNA in our cells,
which contains the
genetic instructions that make us human, is passed on from parent to child along an unending
line of generations.
In addition to imported embryonic stem cell
lines, a campaign was carried out in collaboration with the team of Professor Stéphane Viville in Strasbourg,
which has enabled us to bank 19
lines from embryos discarded during a preimplantation diagnosis because of the presence of a
genetic defect responsible for a severe disease.
We seek to have a better understanding of the
genetic basis and physiological mechanisms of yield potential, from
which we develop elite inbred rice
lines with about 10 % higher yield potential and possess other important traits.
The avian B cell
line DT40, a cell
line which is highly amenable to
genetic manipulation and exhibits a high rate of targeted integration, utilizes both GC and SHM.
Garland's film traces a
line through these cinematic developments all the way back to the genre's roots via such classics as The Fly and The Thing, both of
which explore the horrific possibilities of
genetic engineering.
Breeds with
lines absent of any
genetic diversity, are sadly seen all too often in so many of todays purebreds,
which are riddled with serious health issues, due to * breeder ignorance * and * kennel blindness *.
I have to also confess that my wife, a veterinary geneticist, was in
line for a faculty position at UC Davis where she would take charge of the canine
genetic research that I was a part of,
which I thought might lead to some complications at home.
Hip dysplasia tends to be more common in some breeds than others and in some
lines than others,
which indicates that there is a
genetic component to the disorder.
Finally, there are basic questions about the robustness of the conclusions,
which are based on a new
line of
genetic analysis not previously applied to polar bears.