The possible mechanisms by
which gonadal hormone exposure might protect against the development of bone sarcoma in both males and females are not immediately evident.
Not exact matches
The experience can alter parts of the brain
which in turn control the production of
hormones (known as gonadotropin - releasing
hormones, or GnRH)
which then regulate
gonadal (testicular) development.
Beyond that, high perceived stress strongly affects the control system of most
hormones,
which is the brain / body system known as the hypothalamic - pituitary - adrenal - thyroid -
gonadal (HPATG) axis.
By the time a woman reaches menopause,
gonadal hormone production,
which has been on a slow, steady decline since her 30's, reaches its lowest point.
Your endocrine pathway starts with the hypothalamus, affecting your pituitary,
which in turn affects the function of your thyroid, then adrenals,
gonadal hormones, and finally gut.
Because neutering can be expected to disrupt the normal physiological developmental role of
gonadal hormones on multiple organ systems, one can envision the occurrence of disease syndromes, including those listed below, to possibly be affected by neutering as a function of gender and the age at
which neutering is performed.