Sentences with phrase «which human stem cells»

Since 2009 NIH guidelines have prohibited funding experiments in which human stem cells are injected into primate embryos or in which human - animal chimeras breed.

But its September decision bars experiments in which human stem cells are injected into very early embryos.

They prohibit breeding animals in which human stem cells might have become sperm or eggs, and they rule out primate - human experiments.

Not exact matches

On the logistics end, it is easier to manufacture certain stem - cell therapies, which will be key for human trials like the heart - muscle - regeneration program.

For example, using 3 - D bioprinters — which can print the structure of human tissue with biodegradable material — and stem cells, which are used to populate the 3 - D printed structure, researchers can grow actually human tissue.

For instance, a strong resolution opposing embryonic stem cell research, which destroys human lives, passed with 97 percent support.

The ANT - OAR proposal represent a scientifically and morally sound means of obtaining human pluripotent stem cells that does not compromise either the science or the deeply held moral convictions of those who oppose the destructive use of human embryos for research» which is a creative approach that can be embraced by both the anything - goes camp and the nothing - goes.

Unfortunately, at this formative stage in their lives one viewpoint is pushed to the fore on campus, and that's the opinion that euthanasia, abortion, embryonic stem cell research and a host of other practices which strip humans of their most fundamental right are good things.

«There are perfectly ethical ways of obtaining stem cells to cure disease, which do not involve embryo destruction, so no matter what moral value one places on the human embryo, we do not need to use it.»

Former Governor Martin O'Malley (D — MD) has supported stem - cell research involving human embryos (although he is a devout member of the Catholic Church, which has opposed many forms of embryonic stem cell research).

To understand if cell sex might be an additional important factor influencing outcomes, the team incubated nanoparticles with human amniotic stem cells (hAMSCs) which were extracted from the amniotic layer of placenta attached to male and female fetuses.

The study results were found using mouse embryonic stem cells, which are good cell models for the study of processes seen in human stem cells.

So Daniel Anderson at the Massachusetts Institute of Technology exposed human bone marrow stem cells to biodegradable nanoparticles carrying the human gene for vascular endothelial growth factor (VEGF), which attracts blood vessels to injury sites.

Anand and his colleague Susan McKay started with human skin cells, which they turned into induced pluripotent stem cells (iPSCs) using a tried - and - tested method.

Then, to boost the number of cells, which is another hurdle in tissue engineering, the researchers mixed the chondrocytes with human mesenchymal stem cells from bone marrow.

A team of researchers at the Stanford University School of Medicine has used a gene - editing tool known as CRISPR to repair the gene that causes sickle cell disease in human stem cells, which they say is a key step toward developing a gene therapy for the disorder.

One patient, described in a paper in The Lancet, survived for 2 years after receiving the artificial trachea, which incorporated human stem cells.

But the factor that may make the discovery very significant is that umbilical cord blood can be saved, stored and multiplied without any of the ethical dilemmas facing embryonic stem cell use, which are derived from human fetuses.

With respect to the latter, it states, «no one shall be under a duty to participate in any manner of research on human stem cells to which he has a conscientious objection.»

Dr. Zubair, medical and scientific director of the Cell Therapy Laboratory at Mayo Clinic in Florida, says the experiment will be the first one Mayo Clinic has conducted in space and the first to use these human stem cells, which are found in bone marrow.

Svendsen is more optimistic about his team's work involving human tests of a novel stem cell approach to treat ALS, a degenerative motor neuron disease in which cells that transmit messages from the brain and spinal cord to the muscles wither or die.

The newly discovered human cells, named «cord - blood - derived embryonic - like stem cells» or CBEs, are not quite as primitive as embryonic stem cells, which can give rise to any tissue type of the body.

Wells's team first turned human skin cells into pluripotent stem cells, which can grow into any type of tissue.

The patch is made of eye cells made from human embryonic stem cells, and it has been designed for treating the «dry» form of macular degeneration, which accounts for 90 per cent of all cases, and affects 1.7 million people in the US.

But a number of the invited speakers, including Alan Trounson, president of the California Institute for Regenerative Medicine in San Francisco, and keynote speaker George Daley, a stem - cell scientist at Children's Hospital Boston in Massachusetts, are involved in research using human embryonic stem cells, which the Catholic Church considers unethical.

The stem cells, derived from human umbilical cord - blood and coaxed into an embryonic - like state, were grown without the conventional use of viruses, which can mutate genes and initiate cancers, according to the scientists.

The team used human embryonic stem cells — which can transform into any cell of the body — and cultured them in a mixture of chemicals to grow human brain cells.

This is in stark contrast to much previous work, which has focused on human embryonic stem cells, or hESCs.

In the past year, the South Korean Food and Drug Administration (FDA) has approved the world's first three stem - cell treatments — Hearticellgram - AMI, Cupistem and Cartistem — which followed on the heels of clinical tests for human embryonic stem - cell therapies approved in 2010, according to the health ministry.

Tufts University biomedical engineers recently published the first report of a promising new way to induce human mesenchymal stem cells (or hMSCs, which are derived from bone marrow) to differentiate into neuron - like cells: treating them with exosomes.

More recently, researchers have induced stem cells from diseased human somatic cells, which may serve as new model systems for various illnesses.

To see whether cancer stem cell renewal involves a chain of events similar to that used by embryonic stem cells, and whether the process was affected by oxygen levels, Semenza and graduate student Chuanzhao Zhang focused their studies on two human breast cancer cell lines that responded to low oxygen by ramping up production of the protein ALKBH5, which removes methyl groups from mRNAs.

The results, which are published in the scientific journal Scientific Reports, show that human stem cells that are transplanted to the injured spinal cord contribute to restoration of some sensory functions.

Glioblastomas in lab dishes and mouse brains are fakes, little Potemkin villages that everyone thought were faithful replicas of human glioblastomas but which, lacking tumor stem cells, were nothing of the kind.

The A. Alfred Taubman Medical Research Institute at the U-M Medical School also supported the work, which was reviewed and approved by the U-M Human Pluripotent Stem Cell Research Oversight committee and Institutional Review Board.

The final guidelines on research with human embryonic stem cells issued on Monday by the National Institutes of Health set out criteria for determining which ES cell lines can be used in federally funded experiments and give NIH discretion to approve old lines that don't meet stringent modern ethical requirements.

(This report, which Harvard biologist Eggan calls the «Human Embryonic Stem Cell Misinformation Packet,» prompted a corrective letter from Harvard biologists, who claimed that the White House misrepresented their research for political reasons.)

Attrition of novel drug candidates due to cardiovascular liabilities (including proarrhythmic risk due to delayed ventricular repolarization and Torsades - de-Pointes arrhythmia) remains a hurdle for drug discovery efforts, a hurdle which may be mitigated by the use of human induced pluripotent stem - cell derived (hiPSC)- cardiomyocytes.

But after learning that work by South Korean scientist Woo Suk Hwang had been faked, the journal Science retracted Hwang's landmark papers from 2004 and 2005, which reported the first human embryonic stem cells from cloned embryos.

«You'd still have to ration the therapy,» cautions Robert Hariri, chief researcher at Anthrogenesis in Cedar Knolls, New Jersey, which announced this year that it had morphed human placental stem cells into nerve, blood, cartilage, skin, and muscle cells.

Studies in diabetic rodents suggest that diabetes may alter the intestine's mucosal lining, which is maintained and regenerated by intestinal stem cells; however, little is known about how this occurs and whether it is relevant to humans.

In a study, researchers found that pigs, which have gut bacterial profiles and immune systems similar to humans, also maintain two distinct colonic stem cell populations — ASCL - 2 and BMI - 1.

The finding potentially paves the way for scores of labs to generate new stem cell lines without cloned embryos, which had long been considered the only realistic way of making human stem cells in the short run.

Many scientists argue that so - called research cloning, in which cloned human embryos might be used to produce embryonic stem (ES) cells, could be a boon to medicine.

The researchers coaxed white blood cells from humans and other apes into forming stem cells, from which they grew organoids.

They used the gene editing technology CRISPR to engineer a series of human embryonic stem cell lines, which were identical apart from the number of DNA repeats that occurred at the ends of their HTT genes.

The Hippo signaling pathway, which is highly conserved up to humans, was known to play a critical role in organ size determination, like, for example, in the liver, but has not been demonstrated to influence neural stem cells in the central nervous system.

The method, which involves inserting genetic material that makes the cells» development run backwards, opens the door to stem cells specific to patients, which could be used to repair damaged organs or fight diseases such as Parkinson's and diabetes — crucially, all without the need to destroy human embryos.

Because fertilized human embryos are far more accessible than unfertilized eggs, which can not be frozen and stored, extending the result to humans could lower the practical barriers against creating human embryonic stem cells to study and potentially treat disease.

But Hochedlinger, whose group's paper appears in a new journal called Cell Stem Cell, stresses that researchers still need to study human cells to learn how to reprogram them and have no idea yet which approach would work better in the long run.