In Europe, the legislation for marketing of medicinal products (MP) and IVDs including predictive biomarker - based assays (Companion Diagnostics, CDx) are not directly linked
which is challenging for co-development.
You may find yourself thinking of her in a whole new light,
which is challenging for someone that America wanted to hate.
It is entertaining,
which is a challenge for a film that wishes to paint a bleak portrait.
Parts sharing,
which was a challenge for the company after Daimler - Benz AG's acquisition of Chrysler Corp. in 1998, has been embraced thoroughly to take advantage of DaimlerChrysler AG's global operations.
You also need to trade ETFs in real time when the stock exchanges are open,
which is a challenge for busy people, especially those outside the Eastern time zone.
It also boasts grade 3 - 4 rapids
which are challenging for the experienced and beginners alike!
It nails it more often than other cameras, while preserving more detail, particularly individual strands of hair,
which is a challenge for cameras that rely on depth maps from additional sensors.
The common injuries experienced by veterans include missing limbs, spinal cord injuries, burns, post-traumatic stress disorder (PTSD), hearing loss, traumatic brain injuries, and other impairments —
which are challenges for anyone looking to work after battle.
Social media whether internally or externally facing requires an ongoing commitment
which is a challenge for those who aren't digitally savvy.
Therapy is a place for children to feel safe exploring and processing feelings
which are challenging for them.
I'll explain the different elements that make a strong relationship and we will discuss which are strengths and
which are challenges for you.
This makes them withdraw completely from their new family or display aggressive behavior out of resentment
which is challenging for the new parents.
Because there are so many moving parts, some of
which are challenging for those who've never used a CRM before, we've been doing a scaled roll - in.
Not exact matches
The tariffs,
which have increased frictions with U.S. trading partners worldwide and have prompted several
challenges before the World Trade Organization,
are aimed at allowing the two U.S. metals industries to increase their capacity utilization rates above 80 percent
for the first time in years.
Actual operational and financial results of SkyWest, SkyWest Airlines and ExpressJet will likely also vary, and may vary materially, from those anticipated, estimated, projected or expected
for a number of other reasons, including, in addition to those identified above: the
challenges and costs of integrating operations and realizing anticipated synergies and other benefits from the acquisition of ExpressJet; the
challenges of competing successfully in a highly competitive and rapidly changing industry; developments associated with fluctuations in the economy and the demand
for air travel; the financial stability of SkyWest's major partners and any potential impact of their financial condition on the operations of SkyWest, SkyWest Airlines, or ExpressJet; fluctuations in flight schedules,
which are determined by the major partners
for whom SkyWest's operating airlines conduct flight operations; variations in market and economic conditions; significant aircraft lease and debt commitments; residual aircraft values and related impairment charges; labor relations and costs; the impact of global instability; rapidly fluctuating fuel costs, and potential fuel shortages; the impact of weather - related or other natural disasters on air travel and airline costs; aircraft deliveries; the ability to attract and retain qualified pilots and other unanticipated factors.
«But it seems that launching low - cost long - haul flights without connecting services
is challenging,» Gagey said, pointing to Norwegian Air Shuttle,
which on Thursday reported a bigger than expected loss
for the last quarter of 2017.
Locked
for years near historical lows, all three have started climbing,
which Hartnett says has
been «
challenging bullish consensus.»
With so many potential avenues and platforms to put to work, it
is challenging to know just
which strategies to employ to earn you the most bang
for your limited buck.
If on the other hand, you may
are considering a product into an industry in
which you have no direct experience or connections to guide, you may
be faced with an insurmountable
challenge to the business and the time required to build the right connections
for success may
be infeasible.
The
Challenge: Howard's
is a small Kansas City grocery store, with a twist: The store,
which opened in 2012, sells memberships
for $ 60 per year; members get a door code allowing them to access the store 24/7 and pick from the locally grown produce and organic foods in stock.
The technical
challenge they had embarked on
was indeed daunting, requiring models
for turning speech, with all its nuances and inflections, into neatly labeled data that can
be fed into machine - learning algorithms,
which would then try to extract behavioral patterns from it.
Deciding what to wear when to
which event — so you don't end up looking clueless — can
be overwhelming
for the fashion -
challenged.
A federal appeals court,
which has
been grappling with the FCC's media ownership rules
for more than a decade,
is expected to hear
challenges to the new rules.
Chase offers some great credit cards
for anyone who travels — including the Sapphire Preferred and Reserve — but it can
be challenging to figure out
which of those cards
is best
for you.
That
's what I did
for a series of Cash Diet
challenges,
which tested my ability to stretch my dollar at the grocery store.
Known as the man who reversed the fortunes of Hitachi, Hiroaki Nakanishi
is now preparing the Japanese conglomerate,
which makes everything from elevators to nuclear plants,
for its next
challenge.
While working as a server, stability has frequently
been a
challenge for Ottawa resident Aaron Quinn, who spent seven years at a restaurant
which expected him to work at least one «on - call» shift each week.
The team
is the first all - female team to enter Kari's Tour de Freedom
challenge in
which they will ride an average of 200 km per day
for six days from Esperance to Perth - raising money
for the drug rehabilitation program.
It
's unlikely anyone will have a name in mind,
which presents a big
challenge for Leal in getting the Fix Auto brand name out to consumers.
which sounds like they
're doing it
for themselves and enjoying the change, at least after the initial
challenge.
If anything has gotten easier
for Barkan despite the physical and emotional
challenges that comes with his illness, it
's that the issues he
is now advocating
for are much simpler to explain to people than US interest rate policy,
which has
been his focus at the Center
for Popular Democracy.
The IPO
is the latest in the restaurant and grocery sector,
which has
been met with a ravenous appetite from investors though keeping stocks at their lofty debut prices has
been a tougher
challenge for many.
Austin, who
is currently working on a book tentatively titled Not
for the Faint of Heart,
which focuses on the
challenges faced by those navigating the new economy, predicts that psychologists will
be the next big class of business writers.
Oza's video
is just the latest public relations
challenge for United,
which is still reeling after the forcible removal of passenger Dr. David Dao from an overbooked flight in April bought the airline global condemnation.
Such risks, uncertainties and other factors include, without limitation: (1) the effect of economic conditions in the industries and markets in
which United Technologies and Rockwell Collins operate in the U.S. and globally and any changes therein, including financial market conditions, fluctuations in commodity prices, interest rates and foreign currency exchange rates, levels of end market demand in construction and in both the commercial and defense segments of the aerospace industry, levels of air travel, financial condition of commercial airlines, the impact of weather conditions and natural disasters and the financial condition of our customers and suppliers; (2)
challenges in the development, production, delivery, support, performance and realization of the anticipated benefits of advanced technologies and new products and services; (3) the scope, nature, impact or timing of acquisition and divestiture or restructuring activity, including the pending acquisition of Rockwell Collins, including among other things integration of acquired businesses into United Technologies» existing businesses and realization of synergies and opportunities
for growth and innovation; (4) future timing and levels of indebtedness, including indebtedness expected to
be incurred by United Technologies in connection with the pending Rockwell Collins acquisition, and capital spending and research and development spending, including in connection with the pending Rockwell Collins acquisition; (5) future availability of credit and factors that may affect such availability, including credit market conditions and our capital structure; (6) the timing and scope of future repurchases of United Technologies» common stock,
which may
be suspended at any time due to various factors, including market conditions and the level of other investing activities and uses of cash, including in connection with the proposed acquisition of Rockwell; (7) delays and disruption in delivery of materials and services from suppliers; (8) company and customer - directed cost reduction efforts and restructuring costs and savings and other consequences thereof; (9) new business and investment opportunities; (10) our ability to realize the intended benefits of organizational changes; (11) the anticipated benefits of diversification and balance of operations across product lines, regions and industries; (12) the outcome of legal proceedings, investigations and other contingencies; (13) pension plan assumptions and future contributions; (14) the impact of the negotiation of collective bargaining agreements and labor disputes; (15) the effect of changes in political conditions in the U.S. and other countries in
which United Technologies and Rockwell Collins operate, including the effect of changes in U.S. trade policies or the U.K.'s pending withdrawal from the EU, on general market conditions, global trade policies and currency exchange rates in the near term and beyond; (16) the effect of changes in tax (including U.S. tax reform enacted on December 22, 2017,
which is commonly referred to as the Tax Cuts and Jobs Act of 2017), environmental, regulatory (including among other things import / export) and other laws and regulations in the U.S. and other countries in
which United Technologies and Rockwell Collins operate; (17) the ability of United Technologies and Rockwell Collins to receive the required regulatory approvals (and the risk that such approvals may result in the imposition of conditions that could adversely affect the combined company or the expected benefits of the merger) and to satisfy the other conditions to the closing of the pending acquisition on a timely basis or at all; (18) the occurrence of events that may give rise to a right of one or both of United Technologies or Rockwell Collins to terminate the merger agreement, including in circumstances that might require Rockwell Collins to pay a termination fee of $ 695 million to United Technologies or $ 50 million of expense reimbursement; (19) negative effects of the announcement or the completion of the merger on the market price of United Technologies» and / or Rockwell Collins» common stock and / or on their respective financial performance; (20) risks related to Rockwell Collins and United Technologies
being restricted in their operation of their businesses while the merger agreement
is in effect; (21) risks relating to the value of the United Technologies» shares to
be issued in connection with the pending Rockwell acquisition, significant merger costs and / or unknown liabilities; (22) risks associated with third party contracts containing consent and / or other provisions that may
be triggered by the Rockwell merger agreement; (23) risks associated with merger - related litigation or appraisal proceedings; and (24) the ability of United Technologies and Rockwell Collins, or the combined company, to retain and hire key personnel.
«Any argument they make
for keeping that in would result in the same kinds of legal
challenges presented by Section 3 (c),
which poses the question of, «Why have people from these countries
been deemed more dangerous than others?»»
The
challenge for startups
is three-fold: one, most don't have access to big data; two, most haven't built relational databases from
which data can
be easily pulled; and three, most haven't yet hired a data scientist and a team of analysts.
Cost wins out above all other considerations in the search
for efficiency,
which is why a strengthening US dollar could pose
challenges for Caterpillar.
That account
was questioned in 2013 and 2014 by investigators working
for the Senate Intelligence Committee,
which also issued a lengthy report in December that
challenged the CIA's assertions on the effectiveness of torture.
The U.K.'s
challenges are somewhat different from Canada's: as a result of the Conservative Party's austerity campaign, the U.K.'s economy has suffered more than Canada's,
which has taken more of a Keynesian approach; and the City, as London's financial hub
is known, has had a reputation
for a much looser approach to regulation than that found in either Canada or the U.S. Tal says the U.K.'s finance sector has to change and he expects Carney will attempt to move it in the direction of greater regulation.
Miriam Hernandez - Kakol
is the U.S. Service Line Leader
for KPMG's Customer & Operations business,
which is focused on delivering industry - specific solutions to address the front - and middle - office
challenges of Fortune 500 clients.
But, given the Security and Exchange Commission's lifting last week of an 80 year ban on «general solicitation,»
which prohibited entrepreneurs from publicly discussing private investment offerings, these two archetypal entrepreneurs shed light on the
challenges entrepreneurs seeking funds face and how,
for some of them, the ban's lifting might
be transformative.
The discussions come during a
challenging time
for magazine publishers, many of
which are trying to remake themselves as multimedia entities.
These exchanges bring fresh ideas, new perspectives and different ways of approaching problems,
which are all catalysts
for the innovation
which fuels the economy and help us meet global
challenges, ranging from climate change to fossil fuel dependence and infectious diseases.
SpaceX competes
for military launches with United Launch Alliance, a joint venture of Boeing and Lockheed Martin (lmt),
which was the sole provider
for the Pentagon until Musk launched a campaign in Congress and the courts
challenging what he called an unfair monopoly.
Microsoft,
for example, has reduced itself to heckling Google with two campaigns: «Scroogled,» about the alleged evils of Google's e-mail advertising policy (something that consumers have met with a shrug ever since Gmail's introduction nearly a decade ago); and the «Bing It On
Challenge,» in
which people on the street pick the search results they like best (
which apes the old Pepsi
Challenge — a campaign that defined Pepsi by what it isn't, and thus condemned it to
being Coke's bridesmaid forever).
I think the
challenge for the OEMs
is to demonstrate real value in this relationship,
which means driving Azure adoption and increased utilization.
Guests explore their greatest
challenges and failures,
which makes
for a very humanizing and yet somehow encouraging discussion about what business can
be when the stakes
are highest.
The Trump Administration
is staring down a half - dozen deadlines on trade policy that will create a moment of truth
for the White House,
which has so far opted
for long - term investigations and renegotiations over immediate
challenges to the status quo.
So when the
challenge gets too tough, Logan falls back on what he knows: big, broad comedy —
which works well
for six - second Vines but not so well
for the part of a man who just found out his girlfriend
is getting an abortion.