Sentences with phrase «which is a difficult time»

Tim Kremer, with the New York State School Boards Association, says the original deadline would have meant districts would have to come up with their evaluation system over the summer, which is a difficult time for school officials.

Not exact matches

These risks and uncertainties include, among others: the unfavorable outcome of litigation, including so - called «Paragraph IV» litigation and other patent litigation, related to any of our products or products using our proprietary technologies, which may lead to competition from generic drug manufacturers; data from clinical trials may be interpreted by the FDA in different ways than we interpret it; the FDA may not agree with our regulatory approval strategies or components of our filings for our products, including our clinical trial designs, conduct and methodologies and, for ALKS 5461, evidence of efficacy and adequacy of bridging to buprenorphine; clinical development activities may not be completed on time or at all; the results of our clinical development activities may not be positive, or predictive of real - world results or of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement for the company's products or an increase in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization by the proprietary rights of third parties, or have unintended side effects, adverse reactions or incidents of misuse; and those risks and uncertainties described under the heading «Risk Factors» in the company's most recent Annual Report on Form 10 - K and in subsequent filings made by the company with the U.S. Securities and Exchange Commission («SEC»), which are available on the SEC's website at www.sec.gov.

The story began, «One of the war's top secrets, an amazing machine which applies electronic speeds for the first time to mathematical tasks hitherto too difficult and cumbersome for solution, was announced here tonight by the War Department.»

Still, Didi's global expansion comes at a difficult time for Uber, which is grappling with mounting losses and stricter regulatory scrutiny at home and in Europe.

Grau founded Drivin with long - time friend and neighbor Justin Mahlik, which led to a special challenge: the need to have daily, difficult conversations with a business partner who was a friend first.

First, stop to think about all the ways in which your current life as a consumer is difficult and frustrating — all the ways in which it eats up your own or somebody else's time and still produces unsatisfying results.

Law then published an apology to Miller in the British Press Association, saying «There is no defense for my actions which I sincerely regret and I ask that you respect our privacy at this very difficult time.»

At that time, in Toronto, it was difficult to get enough work in what I wanted to do, which was biotech and pharma projects.

That strange quality of quantum mechanics allows qubits to complete difficult calculations many times faster than traditional bits, which have to be one or zero, on or off, black or white.

Their appearance before Congress comes at an awkward and difficult time for the company, which is under fire from its shareholders and facing a number of ongoing government investigations into drug pricing and distribution, accounting and disclosures, and antitrust matters.

But surely, McCarthy must also be aware that the plus size demographic, which retailers have traditionally found wildly difficult to engage and serve, represents a $ 17 billion market whose time has come.

In these difficult economic times, he offers a way to take control over your media and your brand and ensure that the right things are being said about you — which will surely translate directly into sales and profits.

There are generally more than 800 changes on average to the tax code each year, which means that even full - time CPAs have a difficult time keeping up with them.

Part of this decline in GDP, stemming from the oil production shortfall, will probably be made back sometime in the third quarter, but the net effect on the level of GDP over time will depend on the pace of rebuilding, which at present is difficult to foresee.

Hornsey cautions that despite some immediate changes, which include a new bring your child to work day and an employee resource group dedicated to parents, real cultural change is both difficult and time consuming.

The timing of directly reaching out to the customer is more difficult to achieve with email but this can at least be tackled by customer segmentation which we will talk about shortly.

However, I find it much more comfortable and suitable to my personality to be able to garner investment results that correspond to the internal results of the business, as this eliminates the need to be right about timing, and it eliminates the need to constantly be producing good investment ideas — which is a difficult task to begin with.

The more interesting and difficult case is the one - time price level rise, which takes place over a year or two (or three or four).

Since Jeff is earning and using points all the time (literally), it's difficult for him to pinpoint exactly which cards he utilized for this redemption.

The time constraint and peer business pressures make it very difficult for businesspersons to stay in contact with their stake holders which are very important.

Deducing which platforms are right for you can be difficult and time - consuming, especially considering the endless methods and platforms that are at your disposal for reaching your target audience.

This is particularly difficult because of the ephemeral nature of containers, which can exist for a very short time.

When this happens, it could be a very difficult time for the pharmaceutical industry, which makes the time before the cliff all the more important as companies scramble to shore up their product lines and get their balance sheets in order before their products lose their patent protection [see also Is Your Biotech ETF A Leader Or Laggard?].

Not only that, it's also very difficult to estimate which companies will be the fast growers ahead of time.

This includes application development, which can be difficult and time - consuming.

The first, which is espoused by the article, is that getting persona interviews is too difficult, too time consuming, and / or leads to paralyzing indecision.

I can say I've been beta testing it now for not even 24 hours and it (for me) is the greatest thing for organizing my linking strategy, which as most if not all SEOs realize, is one of the most difficult, time consuming but rewarding processes.

This process can also prove very difficult as an ICO is more likely to rise slowly in value rather than making a huge immediate profit, which means that the investor will have to deal with managing multiple wallets for a long time.

There are so many websites out there offering information that it is difficult to find which ones are actually worth your time.

That covers most of our Scientific understanding, because it's very difficult to move beyond Theory to Law (which is conclusively demonstrated to be 100 % accurate at all times).

We can dislike what they are doing, we can even speak out against things that are not right, yet we are to love them unconditionally, which admittedly, is difficult at times.

In his fair and generally sympathetic review of my book Bergson and Modern Physics, David Sipfle raised some important and significant questions which clearly show how extremely complex the questions concerning the nature of time are and how difficult it is to agree on their solutions even for those who share a basic philosophical view.

It would seem to be preferable to say that: while the crowd clamors and shouts and triumphs and celebrates; while one individual after another hastens to the place of tumult, where it is good to be if one is in search of oblivion and indulgence from that which is eternal; while at the same time the crowd shouts mockingly at God, «Yes, now see whether you can get hold of us»; yet since it is difficult in the rush of the crowd to distinguish the individual, difficult to see the single tree when one is looking at the wood, the sober countenance of eternity quietly waits.

This is a difficult task, because there are so many diverse reasons for the separations, reasons going back to the time of the reformation, reasons which have emerged only later through the historical development of the separated Churches, doctrinal reasons, but also sociological, national, cultural ones which by themselves do not add up to a real denominational difference.

Diodorus writes that, «For as regards the magnitude of the deeds which he accomplished it is generally agreed that Heracles has been handed down as one who surpassed all men of whom memory from the beginning of time has brought down an account; consequently it is a difficult attainment to report each one of his deeds in a worthy manner and to present a record which shall be on a level with labours so great, the magnitude of which won for him the prize of immortality.»

Without a great deal of research and the passage of time it is difficult to know which ethnic groups or what percentage of them will survive as separate cultural entities.

Having woken up at noon (in hotel rooms), they understand why it is difficult to speak of a time in which one must be responsible.

It is difficult to see how, if God's relationship to the world is «wholly other» than the relation of creative spirit to its actual working in time (chronos), we can avoid discounting the Christian significance of creative effort, patient workmanship, and that careful assessment of conditions and consequences which make up so large a part of the wisdom of life.

The public, then, has a difficult time evaluating a major publication such as U. S. News & World Report (December 22, 1997) when it makes the announcement — for which no source is given — that charitable activity was «up 9.5 percent in two years,» a figure that corresponds to AAFRC figures for that time period.

For example, because of his theory of time as asymmetrical, Hartshorne believes we always face a future which is at least partially indeterminate, hence it is even more difficult than MacIntyre admits to determine the narrative order to our lives.

Whereas before the low - audience period of Sunday morning was a difficult one in which to sell commercial time, stations have been able to compensate by selling whole blocks of time to the religious broadcasters.

Yet however difficult this task, and however far from realization it must be in our time and perhaps in every time, to try to fulfill this demand is the obligation which Christian thought must accept for itself.

/ Recall two difficult or bad times which you handled well; be aware of the strengths it took to cope constructively.

It is difficult to consider these four attributes, relating them to Space - Time, without becoming aware of a prospect which, however we may seek to describe it, comes essentially to this:

It's difficult to imagine a cause for time: events require time and are ordered by time such that one can be said to precede another, which is part of what's needed to say that an event is the cause of something.

A couple of years ago when I was going through an incredibly difficult time and dealing with terrible anxiety, God kind of showed me something which helped me see the world differently.

Given how much ink has been spilled on the subject by an obsessed and advocating press, and the strong moral certitude with which Democratic (and occasional Republican) members of the House and Senate are making their evolutionary pronouncements, it is difficult to remember that at this time last year, the issue of gay marriage had much less energy surrounding it.

Ideally, the help line would be live by the holiday season, said Morehead, which is often a difficult time for people struggling with religious doubts.

Rather than take the difficult pastoral road of reminding people that there are circumstances in which some change needs to be made before receiving Holy Communion, we seem to have accepted that everyone should routinely present themselves for the sacrament every time they attend Mass..

From this time on it was difficult for Luther to control publication of his works, particularly of sermons which were taken down.