The Middle East mole rat cells might secrete another chemical, called beta interferon,
which kills cancerous cells.
Not exact matches
Unlike chemotherapy,
which involves administering powerful drugs that
kill both
cancerous and healthy
cells (most healthy
cells can repair themselves), immunotherapies harness the power of the immune system to help it identify and knock out just the
cancerous cells.
Saurabh Saha of BioMed Valley Discoveries in Kansas City, Missouri, and his colleagues wondered whether they could use the bacteria to selectively
kill mammalian
cells within
cancerous tumours,
which often have a poor blood supply and therefore low oxygen levels.
Doctors usually do the most common form of radiation therapy with x-rays,
which can penetrate tissue,
killing the
cancerous cells in deep - seated tumors.
Led by Ludwig Lausanne investigator Alexandre Harari and George Coukos, director of the Ludwig Institute for Cancer Research, Lausanne, the study shows that ovarian tumors harbor highly reactive killer T
cells —
which kill infected and
cancerous cells — and demonstrates how they can be identified and selectively grown for use in personalized,
cell - based immunotherapies.
Based on
cell surface markers known as CD4 and CD8, T
cells generally fall into two broad categories: CD4 — positive helper T
cells,
which ¬ help activate other immune
cells and CD8 - positive cytotoxic T
cells,
which kill cells that are
cancerous or infected with viruses.
A patient receives intensive chemotherapy with or without total body irradiation therapy in an attempt to
kill all
cancerous cells, but
which also destroy his / her own bone marrow function.