Sentences with phrase «which ovarian cells»

Not exact matches

The environment in which cells grow and develop can greatly influence their quality and function, but surprisingly little is known about how the ovarian stroma changes with age.

As a result, the follicle, which contains the ovarian cells and the egg, gets bigger, estrogen levels rise, and the egg matures.

Then the researchers turned to the lab, where they exposed human liver, breast, colon, ovarian, and other cancer cells to the drugs, which appeared to make it easier for the cells to migrate.

That ovarian tissue bears clusters of cells known as primordial follicles, which surround immature precursors to egg cells.

Their findings in the study «Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells,» which has been published in The Journal of Cell Biology, suggest that this FDA - approved ovarian cancer medicine has the potential to treat a wider range of cancer types than currently indicated.

To test this idea, they experimentally reduced the expression of the DNM30S lncRNA, which resulted in reduced ovarian cancer cell migration and invasion.

That geometry directly links to whether or not the ovarian follicles, organized hormone - producing support cells surrounding an immature egg cell, will survive in the ovary, which was one of the bigger findings in the study.

For the new study, described in the October 23rd issue of Nature Communications, scientists at the Johns Hopkins Kimmel Cancer Center and Dana Farber Cancer Institute in Boston collected tissue samples containing normal cells, ovarian cancers, metastases that had spread elsewhere, and small cancers found in the fallopian tubes, which included single cell layers of cancer called «p53 signatures» and serous tubal intraepithelial carcinoma, or STIC lesions.

Those findings are among results of six studies of investigational chimeric antigen receptor (CAR) T cells for both adult and pediatric leukemias, adult lymphomas, and ovarian cancer which will be presented during the 2016 American Society of Clinical Oncology Annual Meeting.

Led by Ludwig Lausanne investigator Alexandre Harari and George Coukos, director of the Ludwig Institute for Cancer Research, Lausanne, the study shows that ovarian tumors harbor highly reactive killer T cells — which kill infected and cancerous cells — and demonstrates how they can be identified and selectively grown for use in personalized, cell - based immunotherapies.

In the proposed project, Dr. Lampi Hermanson will produce NK cells from stem cells, inserting a chimeric antigen receptor (CAR) with the capacity to recognize mesothelin cells, which is expressed in 70 % of ovarian cancer patients.

The book introduces the incessant menstruation hypothesis, which may allow physicians to better understand and explain to patients why many serous ovarian cancers may actually be originating from the fimbriated end of the fallopian tube and why endometrioid and clear cell cancers may arise in association with endometriosis.

Olaparib is a PARP inhibitor, which is already used to treat certain ovarian cancer patients and prevents damaged cancer cells from repairing themselves after chemotherapy or radiotherapy.

The approach developed by the MGH team starts with the engineered protein, which in this case fuses an antibody fragment targeting a protein called mesothelin — expressed on the surface of such tumors as mesothelioma, ovarian cancer and pancreatic cancer — to a protein from the tuberculosis bacteria that stimulates the activity of dendritic and other immune cells.

The scientific basis of this case report of successful ovarian rejuvenation is most likely that the patients» blood cells, which were injected into her ovaries, produced substances called Growth Factors, which the body normally produces in order to heal both internal and external injuries.

Red foods like red bell peppers and tomatoes contain a phytochemical called lycopene, which may have an anti-inflammatory affect on the cells lining the heart and blood vessels, and may reduce the risk of developing prostate cancer among other cancers such as breast, lung, bladder, ovarian, and colon.