Sentences with phrase «which patients»

Ratain's team also developed and patented a test that determines which patients are likely to have a serious adverse reaction to the drug.

This receptor was the first and most important biomarker in breast cancer and can predict which patients respond to anti-estrogen treatment.

Dr. Huizing also studies other sialic acid - related diseases, including sialuria, a progressive disease in which patients produce excess sialic acid.

Small, focused clinical trials are possible for certain B - cell malignancies such as Diffuse Large B - Cell Lymphoma in which patients can be stratified based on NF - kB activation status and / or presence of mutations known to activate NF - kB.

Ann Arbor, MI (OBBeC)- As early as one week after beginning treatment for brain tumours, a new imaging analysis method was able to predict which patients would live longer, researchers from the University of Michigan...

«With the expansion of the number of subjects enrolled in our clinical trial, we are actively analyzing the trial data across a range of factors to determine which patients are best suited for AST - OPC1,» stated Dr. Edward Wirth III, Chief Medical Officer.

It is unclear how best to identify which patients are likely to benefit, or not to benefit, from palliative chemotherapy.

The results suggest that assessing baseline QoL in women with PRR - ROC might help identify which patients are unlikely to benefit from palliative chemotherapy, said lead study author Felicia Roncolato, MBChB, FRACP, of St. George Hospital in Sydney, Australia, on behalf of the Gynecologic Cancer Intergroup Symptom Benefit Group.

But which patients will benefit from surgery and which will not, because their risk of cancer recurrence is too high?

But which patients will benefit from surgery and which will not, because their...

The possible expansion of the trial under the PMI ® will include adding new genetically targeted therapies to which patients can be matched and expanding the number of genetic alterations being studied in the trial.

By understanding why this happens, we may be able to predict in advance which patients will respond to the surgery.»

When these mechanisms are better understood, researchers will be better able to predict which patients will respond best to microbiome treatments, Kahn says.

Understanding which patients will respond well to immunotherapy is important and thus far has proved difficult.

Two Örebro researchers have together with European colleagues been awarded EUR 34 million, almost SEK 340 million, to develop a blood test that will enable healthcare professionals to identify which patients suffering from fatty liver are at risk from...

The comprehensive information can be used to predict a patient's risk of developing invasive candidiasis in the hospital and to predict which patients may not come to their doctor's appointments.

But they haven't known exactly which patients might safely skip the toxic treatment.

Indiana University researchers have been awarded a $ 1.4 million grant from the National Institute on Drug Abuse for a study that will use social network analysis to examine «doctor shopping,» in which patients visit multiple physicians to get prescriptions for controlled substances.

Researchers then determined which patients had been taking a statin and for how long before Parkinson's disease symptoms appeared.

WET involves five trauma - focused sessions in which individuals are asked to write about their traumatic experiences followed by scripted instruction, while CPT is a 12 - session program in which patients are taught to recognize and challenge dysfunctional cognitions about their traumatic event and current thoughts about themselves, others and the world around them.

Chronic stroke, in which patients suffer from permanent infirmity, is the leading cause of adult disability in the developed world.

The lack of knowledge and tools highlights the importance of ongoing research leading to the development of better diagnostic tests and biomarkers that can predict which patients are at risk for progression from latent to active disease, as well as better - tolerated treatment regimens for latent TB infections, note the authors.

A clinical trial, funded by the Pancreatic Cancer Action Network, has been started to see if these analyses can predict which patients at risk for pancreatic cancer will develop tumors.

It also gives us a marker of disease that might prove valuable in the clinic to predict which patients have a more aggressive cancer.

What are the molecular and cellular mechanisms by which patients with certain chronic diseases have increased or decreased risks for developing cancer, and can these connections be exploited to develop novel preventive or therapeutic strategies?

She said that because there was no interval of time within which these patients were more likely to develop depression, any screening should be done at regular intervals of time to avoid missed opportunities to intervene.

New tools are needed to help define which patients with latent TB infection outside these epidemiologically defined groups are at high risk for progression.

Now a new study from the Abramson Cancer Center of the University of Pennsylvania found that shifting use of anti-PD-1 drugs to before surgery may provide clues about which patients will benefit and which may be at increased risk for recurrence.

First, two so - called localizer scanning sessions were conducted in which the patients were instructed to alternate 30 - second periods of mental imagery with 30 - second periods of rest.

The degree to which patients are empowered by written educational materials depends on the text's readability level and the accuracy of the information provided.

«Our findings suggest new ways of tackling the still - difficult task of working out which patients should receive which drug and how drugs should be combined to maximize therapeutic benefit,» said senior study author Peter Sorger, the Otto Krayer Professor of Systems Pharmacology and director of the Harvard Program in Therapeutic Science and the Laboratory of Systems Pharmacology at Harvard Medical School.

* Stratification of the patient population into lower and higher complexity to identify which patients could be cared for using the standardized model

«More studies are needed to uncover the exact mechanisms involved, but we predict that direct treatment with D4A could prolong survival in some patients with metastatic prostate cancer,» said Dr. Sharifi, «Further studies will also help us develop a potential biomarker profile to predict which patients will respond to D4 — abiraterone.»

However, currently there is no way of accurately predicting which patients with MGUS are likely to go on to get myeloma.

Apart from help in developing new drug treatments for COPD, the study is important for understanding whether there may be distinct subtypes of COPD in which patients respond differently to treatment.

It could be used to help decide which patients could benefit from being enrolled into clinical trials, as well as to measure the quality of care, he added.

Can we identify some signature in the pattern of collagen that will help us understand which patients are going to do well and which are not?

«There hasn't been a reliable way to predict which patients with glaucoma have a high risk of rapid vision loss,» said principal investigator Rajendra S. Apte, MD, PhD, the Paul A. Cibis Distinguished Professor of Ophthalmology and Visual Sciences.

Might collagen patterns also help us sort out which patients should undergo surgery?

Researchers wanted to determine which patients were more likely to experience hot flashes to help physicians make treatment decisions.

The researchers are also conducting a Phase 2 trial in which patients receiving ART are switched to antibody treatment.

Unfortunately, there's no way to accurately predict which patients might lose vision most rapidly.

Personalized medicine can also increases patient safety, as patient profiles indicate which drugs are suited for which people, at what dose, and which patients might suffer from adverse drug reactions.

Mutations in the protein, otoferlin, are linked to severe congenital hearing loss, a common type of deafness in which patients can hear almost nothing.

I began to wonder if he had trichotillomania, an obsessive - compulsive condition in which patients pull out their hair.

«This study is a concrete step towards identifying which patients are more likely to experience these distressing symptoms,» said Mayer Fishman, M.D., Ph.D., senior member of Moffitt's Genitourinary Oncology Program.

Currently, lung function is measured using a test known as spirometry, in which patients blow through a tube; their progress is tracked over time.

«We need to confirm this synergistic activity of vemurafenib and cediranib across a broader range of melanoma models, investigate why the particular combination is effective, and find biomarkers that predict which patients with BRAF - mutant melanoma should receive this combination,» says Friedman, who is a research fellow in Dermatology at Harvard Medical School.

«Prolonged repetitive physical workload increases risk of developing rheumatoid arthritis: New insights into which patients are genetically more susceptible.»

In addition to aiding the search for better depression drugs to help placebo non-responders, the new study could help identify which patients might benefit from non-drug strategies known to help people who don't get relief from antidepressant drugs.