Sentences with phrase «which plaque forms»

They may pave the way for better diagnosis of neurodegenerative diseases, such as Alzheimer's disease, in which plaque forms from the amyloid beta or tau proteins.

Not exact matches

Have a higher prevalence of stroke, atherosclerosis [a common form of arteriosclerosis in which fatty substances form a deposit of plaque on the inner lining of arterial walls], chronic obstructive pulmonary disease (COPD), Crohn's disease, lymphoma, metabolic syndrome [a collection of heart disease risk factors], cancer, and liver disease.

Specifically, rodents genetically modified to express human amyloid precursor protein (hAPP), which can lead to the debilitating plaques that form in the brains of Alzheimer's patients, seem to struggle to find the hidden platform relative to their healthy peers.

IRON overload may accelerate Alzheimer's disease, according to research that also reveals the role of beta - amyloid precursor protein (APP), which forms plaques in affected brains.

In a brain ravaged by Alzheimer's, microtubules, which are crucial to cell communication, disintegrate as tau proteins (blue) form tangles and amyloid proteins (green) form plaques.

When these plaques burst a blood clot is created, which in turn could cause stroke or heart attack, depending on how and where the blood clot is formed.

These plaques, which are believed to cause the dementia associated with the disease, are made up of tangles of amyloid beta (Aβ), a protein that is found in soluble form in healthy individuals.

While previous investigations into the protein's effects have used either mice in which gene expression was knocked out or transgenic animals that expressed human gene variants throughout their lifetimes, the MGH - MIND - led study used a different approach to investigate the effects of introducing the variant forms of the protein into brains in which plaque formation had already begun.

Previously, researchers have shown that treating cells with neuregulin - 1, for example, dampens levels of amyloid precursor protein, a molecule that generates amyloid beta, which aggregate and form plaques in the brains of Alzheimer's patients.

The disease is largely attributed to an abnormal buildup of proteins, which can form amyloid beta plaques and tangles in the brain that trigger inflammation and result in the loss of brain connections called synapses, the effect most strongly associated with cognitive decline.

To better explain this finding, the team turned to yet another protein, amyloid beta — which in its soluble form, before building up and hardening into plaques, has already been found to be toxic to the synapses.

The drug also appeared to reduce the amount of the protein amyloid beta (which forms toxic plaques in the brains of Alzheimer's patients) by decreasing the levels of metals such as zinc and copper.

These findings hold exciting clinical implications.When the researchers blocked the CD36 receptor in mice with atherosclerosis (in which cholesterol thickens the arteries), the cytokine response declined, fewer cholesterol crystals formed in plaques, and inflammation decreased.

Just a few years ago, William Klunk and his colleagues at the University of Pittsburgh, Pennsylvania, announced that they had come up with a compound that binds selectively to amyloid, the protein from which up the characteristic Alzheimer's plaques are formed.

It binds to the beta - amyloid plaques that characterize Alzheimer's disease, helping to measure the extent to which plaques have formed in different brain regions.

They form plaque and produce acid, which starts damaging teeth.

The nature of those plaques finally came into focus in 1984, when George Glenner, a research scientist at the University of California, San Diego, identified the peptide called amyloid - beta and hypothesized that Alzheimer's was caused by «amyloidosis» of the brain, a process in which insoluble forms of an amyloid protein accumulate.

Glenner's research eventually morphed into the «amyloid cascade hypothesis,» which says that the formation of amyloid - beta plaques leads to tangled forms of another protein, tau, and ultimately to inflammation in the brain.

This project is relevant to Alzheimer's and Parkinson's diseases in defining the mechanisms by which amyloid plaques and other insoluble aggregates form in brain tissue.

Within two months, those derived from the Alzheimer's patients began secreting high levels of amyloid protein, which clumped together in the spaces between neurons, resembling the formation of plaques in a fully formed brain.

Disease - linked mutations in these genes result in increased production of the 42 - amino - acid form of the peptide (Abeta42), which is the predominant form found in the amyloid plaques of Alzheimer's disease.

The fatty plaques attract white blood cells, grow larger, and can form blood clots, which can cause a heart attack.

Studies indicate that hawthorne berry prevents plaque from forming along the arterial walls and reduces cholesterol levels, which helps lower blood pressure.

The compound sticks to the free - floating forms of the protein amyloid, which build up into damaging plaques in the brain.

In addition, refined carbohydrates set the stage in the blood vessels for inflammation, which allows dangerous artery - clogging plaques to form in the first place.

To me it seem like plaques form when the blood becomes «saturated» with cholesterol and it «precipitates» out in the walls of the arteries where it is eaten by immune cells which turn into foam cells when they become engorged with cholesterol.

The cause of heart attacks and strokes is inflammation of the arteries which causes plaque to form and get calcified.

Atherosclerosis refers to the narrowing of the arteries due to excess cholesterol forming plaques within the arteries, which leads to compromised blood flow.

The cause of heart disease is not animal fats and cholesterol but rather a number of factors inherent in modern diets, including excess consumption of vegetables oils and hydrogenated fats; excess consumption of refined carbohydrates in the form of sugar and white flour; mineral deficiencies, particularly low levels of protective magnesium and iodine; deficiencies of vitamins, particularly of vitamin C, needed for the integrity of the blood vessel walls, and of antioxidants like selenium and vitamin E, which protect us from free radicals; and, finally, the disappearance of antimicrobial fats from the food supply, namely, animal fats and tropical oils.52 These once protected us against the kinds of viruses and bacteria that have been associated with the onset of pathogenic plaque leading to heart disease.

Oxidized Cholesterol can form plaque in the blood vessels walls, which can lead to heart attack or stroke.

Apples promote saliva production, which prevents plaque from forming.

They also contain phytonutrients that prevent cell adhesion to blood vessels and forming plaque buildup, which maintains healthy blood pressure and improves blood circulation.

It causes a thick coat of mucuous to form, which sticks and lines the walls of your large intestine (called mucoid plaque).

Another major problem which leads to atherosclerotic plaque, heart attacks and strokes is the tendency of the platelets and red blood cells to stick together in clumps and form clots.

If the plaque is disturbed or bursts, blood platelets can accumulate at the site and form a clot, which can grow until it completely blocks an artery and cuts off the oxygen supply to the heart, brain, or other body part.

Personally, I would use dentistry to correct any rotten or painful teeth, followed by a good quality raw diet, and an all - natural water additive called Healthy Mouth (which kills off plaque forming bacteria).

«White» teeth appear clean and unproblematic, but unseen plaque, which is an accumulation of bacteria, will build up and form calculus (tartar).

Caused by bacteria which, if left unchecked, form a layer of a sticky residue called plaque over the teeth of an animal, Periodontal disease (PD), will often begin very early in a pet's life.

It results from the buildup of sticky plaque, which includes bacteria, proteins, and food that solidifies to form calculus on the teeth.

The Gel Has an added Enzyme that helps form a protective barrier on the teeth to help prevent plaque and tartar build up which causes bad breath and potentially other diseases throughout the body.

This is because Oravet Dental Chews contain a special ingredient, delmopinol, which works to form a preventive barrier that blocks bacteria, and the future formation of plaque and tartar that builds up over time.

Plaque and tartar that build - up on your pet's teeth can lead to bacterial infections, and gingivitis, which can progress to more advanced forms of periodontal disease.

These bacterial grow to form plaque which is a combination of bacteria, mineral and decomposed food.

Gingivitis Bacteria and plaque - forming foods can build up on your pet's teeth and harden into tartar, which causes inflamed gums, Gingivitis.

Bacteria forms on food particles caught in their teeth, which combines with saliva to form plaque.

When plaque hardens, it forms tartar (or calculus), which in turn can cause the gums to get red, inflamed, and sore.

It begins with deposits of plaque which harden to form tartar.

Bacteria stick to the smooth tooth surfaces forming plaque, which thickens, mineralizes, hardens and roughens into calculus, also known as tartar.

The process is simple but merciless: Plaque, which is made of saliva, sloughed mouth cells, food, and other things, forms on teeth just minutes after eating.

As this mixture builds up in her mouth, it begins to form plaque, which eventually hardens into tartar and discolors your kitten's teeth.