Sentences with phrase «which precise gene»

Still, which precise gene or genes behind the changes remained a mystery.

Not exact matches

Using gene - sequencing technology, researchers established that the precise segment of the pup's DNA «switched on» by the act of grooming was the part that controlled the future function of the hippocampus, which processes stress hormones.

Schrödinger didn't think there was a correspondence between each part of the gene and precise biochemical processes, which is what a code implies.

So, I'll just say a little more about why yeast; which is, over the decades, yeast molecular biologists have devised so many powerful tools that allow you to make very precise changes in yeast, in their DNA; exquisite control, where you can change a single base that you want in a particular place, you can put a whole gene in, take a whole gene out, swap genes etc..

Denis Duboule and his colleagues at the European Molecular Biology Laboratory in Heidelberg, working with mice, showed that genes in the Hox - D cluster, which define the head - to - tail body axis, are activated one after another and at a precise time during development of the embryo.

Embryonic development is a well - studied process in which the precise regulation of gene expression is critical, since many genes are expressed simultaneously and in a punctual manner.

For example, we still don't even have a precise definition of «stemness,» noted Ali Brivanlou of Rockefeller University, who is doing studies to see exactly which genes get up - or down - regulated at what stages in ES cell development.

Caribou's market - leading CRISPR - Cas9 gene editing technology can accurately target and cut DNA to produce precise and controllable changes to the genome, which can be applied by JAX to create mouse models that better recapitulate human diseases enabling researchers to find better treatments faster.

Critically, gesicles do not result in persistence of the Cas9 endonuclease, which in turn reduces the chances of off - target effects and provides precise control of the dose and timing of gene editing.

Dr. Eng and team create scoring system to facilitate identifying individuals to be referred to PTEN gene testing Researchers have discovered a method for more precise identification of individuals who should undergo testing for genetic mutations of the tumor suppressor gene PTEN, which associates with a variety of conditions including several types of cancers.

Debate about so - called germline editing of eggs, sperm and embryos has been going on for decades, but it has come to a head in recent years with the development of a powerful new gene - editing technology called Crispr - Cas9 that can make extremely precise edits to DNA and which was used by the Chinese team and would be used by the British team.

And doctors at the Great Ormond Street Hospital in London recently reported using a similar gene - editing technique called TALENs, which also recognizes and cuts precise DNA sequences, to engineer immune cells for a therapy that may have cured two infants of leukemia.

The bromodomain containing protein 9 (BRD9) has been reported as a component of the switch / sucrose non-fermentable (SWI / SNF) brahma - related gene 1 - associated factor (BAF) complex, which plays a key role in chromatin remodelling and transcription control [1] although the precise biological role is unknown.

This includes targeting gene - editing technologies like CRISPR, which has recently opened up new doors for precise genome manipulation and gene therapy.

Numerous mouse models have been generated to examine the pathogenesis of the disease and to evaluate therapeutic approaches, but the most precise genetic reproductions of the human condition are the knock - in (KI) mouse models which express the huntingtin mutation in the proper genetic and protein context on the murine gene.

Jack Russells are apparently even more problematic for the markers because they aren't recognized by the AKC, the breed markers are less precise than other breeds which have more consistent gene pools.

The gene product's precise role is not currently understood but it is thought to anchor regulatory complexes at the photoreceptor connecting cilium, which acts as a bridge between the inner and outer segments of photoreceptor cells [43] as well as having functions in disk morphogenesis [42] and in the structure of the ciliary axoneme [44].