Sentences with phrase «which signal transduction»

Not exact matches

Among these was the protein VGLUT1, which is essential for signal transduction in specific nerve cells.

SU101 targets the signal transduction activated by a messenger called platelet - derived growth factor, which controls the genes involved in tissue formation and wound healing.

The scientists would like to investigate how signal transduction is achieved in grasses whose vascular bundles are structured differently in comparison to Arabidopsis which belongs to the Brassicaceae family.

FosB is a transcription factor in the brain which, together with other molecules, is involved in so - called signal transduction (transmission of stimuli to the cells), that is to say conveys genetic information between the cells and also determines whether certain genes are activated or not.

Intra - and intermolecular signal transduction mechanisms in membrane - embedded (photo --RRB- receptor / transducer complexes are studied using the photoreceptor / transducer complex NpSRII / NpHtrII, which is responsible for the photoactive behavior of the halophilic archaeon Natronomonas pharaonis.

His graduate and postdoctoral work led to seven first author papers in the Journal of Biological Chemistry, including four back - to - back papers on fundamental characterization of arachidonic acid pathways, and a Cell paper, which was the first to demonstrate cAMP - independent G protein participation in receptor - mediated signal transduction.

Klemke's interests, and what he envisions to be the future of signal transduction research, is finding which of these signals are active — which are phosphorylated and dephosphorylated, for instance — during cancer cell metastasis.

Deletion of DGKζ from T cells results in prolonged TCR signal transduction downstream of DAG, resulting in enhanced activation of Ras, increased effector T cell proliferation, and amplified cytokine production, which leads to increased antitumor activity against s.c. implanted EL4 tumors or murine mesothelioma (12, 16, 17).

Recently, interest has developed regarding the possibility of targeting intracellular inhibitory proteins to improve T cell activity against cancer, including diacylglycerol kinase ζ (DGKζ)(9, 10) and Casitas b - lineage proto - oncogene b (Cbl - b)(11), which attenuate signal transduction events downstream of the TCR and CD28.

Figure 3A shows results of four control experiments, consisting of transgenic plants that lack one component of the complete signal transduction system (lack the receptor, lack the transmembrane HK, or lack the modified response regulator) or in which the critical phospho - accepting Asp53 residue was mutated.

Increased expression of transcription factor ATF2 — which is required for the amino acid depletion responses of genes such as ATF3, CHOP, SARS and 4EBP - 1 — is mediated by a signal transduction pathway that appears to involve an amino acid sensing GPR [37].

The AR is able to integrate into a composite signal transduction that acts as a conduit which will lead to a much bigger expression of certain genes.

This is in contrast to high carbohydrate low fat nutritional intervention, which actually fixes a broken system (elevated insulin levels and interference in signal transduction) and can result in actual reversal of the disease over time.