Sentences with phrase «which synaptic connections»

Building on their previous work that identified and activated memory cells, a group led by RIKEN Brain Science Institute and RIKEN - MIT Center Director Susumu Tonegawa has now shown that spines — small knobs on brain - cell dendrites through which synaptic connections are formed — are essential for memory retrieval in these AD mice.

Not exact matches

Geoff Hinton, a leading neural networking theorist, argues the hardware is useless without the proper «learning algorithm» spelling out which factors change the strength of the synaptic connections and by how much.

They used a somewhat bizarre technique in which two mice were sutured together in such as way that they shared a circulatory system (known as parabiosis), and found old mice joined to their youthful counterparts showed changes in gene activity in a brain region called the hippocampus as well as increased neural connections and enhanced «synaptic plasticity» — a mechanism believed to underlie learning and memory in which the strength of neural connections change in response to experience.

Most researchers interpret this activity as the brain slowly reinforcing synaptic connections that already exist, but Tononi noticed that after each wave, the brain goes completely silent, which never happens when we're awake.

It occurs when one neuron fires closely after another, which strengthens their synaptic connection and makes it slightly more likely the first will trigger the second in the future.

The brain is a soft, squishy organ, which has evolved over millions of years, and its synaptic connections are not electronic but electrochemical (hence our sluggish ability to solve equations, compared with a computer's speed).

After conducting studies in both humans and mice, the researchers said this new schizophrenia risk gene, called C4, appears to be involved in eliminating the connections between neurons — a process called «synaptic pruning,» which, in humans, happens naturally in the teen years.

Over-activation of the D2 class of dopamine receptors led to suppression of the function of NMDA receptors, which are activated by the neurotransmitter glutamate, at the synaptic connection between hippocampus and prefrontal cortex.

«After a year of sound deprivation, we observed dramatic changes in the inner ear — notably, a significant loss of the synaptic connections through which the sensory cells send their electrical signals to the brain,» Dr. Maison said.

The human brain contains as many as 100 billion neurons, most of which make hundreds to thousands of synaptic connections with specific target cells.

When ASD astrocytes (red) are cultured with ASD neurons (red) neuronal development is impaired; the neuron has a smaller cell body, extends less dendritic processes which are thick and stunted, and receives less synaptic connections.

Because subunit composition can influence the docking between hemichannels [14], it might be possible to pattern synaptic connections through selective expression of innexins, of which 25 exist in C. elegans (reviewed in [1]-RRB-.

EHT creates stronger neural connections, which lead to the ability to create stronger synaptic connections.