Sentences with phrase «which tumor»

Medical experts note that the findings could launch a medical revolution in which every tumor can be targeted with personalised therapy.

The findings could herald a medical revolution in which every tumor can be targeted with personalized therapy.

In advanced mammary cancers where metastasis has occurred or in which the tumor is fixed to the underlying tissues, surgery will not be curative but may be considered an option to reduce local tumor - burden and improve quality of life.

One of the criteria used to select a treatment method is the degree to which the tumor is localized in one defined place.

I think that many instances of suspected brain tumors might turn out to be other things if post mortem examinations were done — and that there would also be a lot of cases in which a tumor was not diagnosed when one was actually present.

These, together with the origin or type of tumor, the grade (differentiation or degree with which the tumor cells resemble normal cells) and stage (how large it is and extent of spread) indicate how the cancer will behave (the prognosis).

Who gets which tumor and when is a complex process in which many factors interplay — genes, lifestyle, nutrition, etc..

Lymph node mapping, a technique to visualize the lymphatic drainage of tumors by which tumor cells might spread, is increasingly used to improve cancer staging and treatment protocols in the treatment of cancer in humans.

«By bringing our research together, we want to illuminate pathways by which tumor cells and HIV evolve to avoid immune system attacks and use this knowledge to identify new targets for prevention and treatment for both diseases.»

The knowledge about how this cancer form arises and develops is still limited but new results from a research team led by Lene Uhrbom, Uppsala University / SciLifeLab, shows that disease progress and the malignancy are affected by the cell type from which the tumor originates as well as the age of the patient.

Among his most important accomplishments was the description of a key mechanism by which tumor cells can escape the host immune system.

«However, therapies targeting these alterations have not improved clinical outcomes, most likely because they have systematically failed to eradicate the proteins to which the tumor is «addicted,»» said Dr. Iavarone.

«Our study pinpoints a novel way in which tumor cells not only survive but actually continue to divide in spite of a low oxygen environment.

The researchers grafted breast or lung tumors in mice, allowed the tumors to grow to small size and removed these tumors surgically — essentially mimicking the situation in a human tumor patient in which the tumor is surgically removed as soon as possible after diagnosis.

The stereotactic ablative radiation therapy (SABR) was used to treat inferior vena cava tumor thrombus (IVC - TT) that reached the heart, a complication of kidney cancer in which the tumor extends into the venous system − the system of veins that return blood to the heart.

Another view is that tumors can become resistant to therapy by a process called cell fate decision, by which some tumor cells are killed by therapy and others become cancer stem cells.

A significant finding by the team was that either the mutant KRAS gene or another cancer gene is amplified, depending on which tumor suppressor gene is affected and to what degree its function is impaired.

However, the mechanisms by which tumor cells interact to enhance the spread of cancer remained unclear.

«Conventionally, lymphatic vessels are regarded mainly as passive conduits through which tumor cells spread from the primary tumor and eventually metastasize,» he said.

The scientists have shown that, in all cancers, a sort of «identity crisis» is observed in cancerous cells: in the organs or tissues in which a tumor develops, genes specific to other tissues or to other stages of the development of the organism express themselves in an aberrant manner.

«If we can identify the point at which tumor cells acquire the characteristics of stem cells, it will be possible to look for ways to interrupt the process and avoid progression of the disease.»

Right now, that data is locked up in electronic health records, which tend to be organized to help bill insurers, rather than detail, say, the rate at which the tumor is shrinking, in a way that could be pulled out for a study.

«Novel mechanism by which tumors evade cancer immunotherapies.»

A Ludwig Cancer Research study led by Benoit Van den Eynde, Director of Ludwig Brussels, has identified a novel mechanism by which tumors of the aggressive skin cancer melanoma can resist cancer immunotherapy.

«The effective immune response didn't happen in every tumor model we tested, so we still need to figure out exactly what triggered the tumor shrinkage and how to predict which tumors will shrink in response to virotherapy,» said Leddon, who is also working toward her medical and doctoral degrees at the University of Cincinnati.

Possibly, this is because the body can recognize which tumors are more aggressive and react to them,» said Balla.

Twenty of the 23 patients had a measurable response to the treatment, with four achieving a complete response — in which no detectable tumor was left — and 16 having a partial response — in which their tumors shrank to less than half their original size.

Johns Hopkins researchers say they have identified a set of genes that appear to predict which tumors can evade detection by the body's immune system, a step that may enable them to eventually target only the patients most likely to respond best to a new class of treatment.

Pembrolizumab and nivolumab, for example, the newest inhibitors to win FDA approval, target a checkpoint called PD - 1, through which tumors can induce a T cell to deactivate.

Still, says Parada, having three examples in which tumors seem to harbor cancer stem cells suggests there will be more.

In some cases such as ovarian cancer, however, drug - free intervals are needed to allow patient recovery from side effects, during which tumors can sometimes begin to grow again or develop resistance to the drugs being used.

In particular, the combination reduced tumor growth and angiogenesis, the process by which tumors recruit blood vessels to feed their expansion.

Glioblastoma, is an aggressive cancer in which tumors grow rapidly and spread rapidly to new sites.

These adrenal gland tumors are often benign, but they can become malignant, and in some cases lead to life - threatening hypertension, arrhythmia, and stroke, but it's not clear which tumors will become metastatic because of the disease's rarity and complex biology.

A Ludwig Cancer Research study has uncovered a key mechanism by which tumors develop resistance to radiation therapy and shown how such resistance might be overcome with drugs that are currently under development.

A new approach to analyzing prostate gland tissue may help address a major challenge in treating prostate cancer - determining which tumors are unlikely to progress and which could be life threatening and require treatment.

In this case, they would target proteins associated with the Epstein Barr virus, which the tumors would express.

The goal is to understand which tumors will be difficult to treat and to find out why certain cancer drugs lose their effect after a period of use.

But what Kim and Berry really want in their arsenal are precision treatments that target specific pathways in the retinoblastoma tumor, as well as information on which tumors might be resistant to chemotherapy.

It has also been found to increase the rate at which tumors grow.4

This not only helps researchers track which vaccines are associated with which tumors but also moves vaccination away from the area between the shoulder blades where a cat is likely to have had many vaccines administered in the past.

Many breeds appear to be predisposed, especially Boxers and Pugs (in which tumors are often multiple), Rhodesian Ridgebacks, and Boston Terriers.

Not exact matches

Our partner physicians use data and analytics to do exactly what you described, which is to determine the best protocol for patient care — disease and tumor - specific — so they don't over-treat or waste resources.

The institute's Tumor Neoantigen Selection Alliance, which includes Bhardwaj's team and others from the University of Pennsylvania and to Stanford Medicine, is focusing on discovering «cancer markers» and then making predictions on neoantigens to combat them.

The institute, which includes over 40 laboratories and more than 300 researchers, said the research would focus on modifying a patient's own immune system T - cells to target a tumor, studying ways to boost patient response to current immunotherapy drugs.

He was treated in 2014 for a cancerous brain tumor, which was removed, and underwent preventative chemotherapy afterward.

But the two organizations see the promise of replacing pricey and complicated biopsies with Guardant Health's technique, which can suss out genetic mutations in the little shreds of tumor DNA that are left in the blood stream.

Chicago, GenomeWeb — A new study by researchers from Memorial Sloan Kettering Cancer Center has demonstrated the predictive power of an AR - V7 protein expression test using Epic Sciences» non-EPCAM-based circulating tumor cell detection platform, which could help guide treatment decisions for men with metastatic castration - resistant prostate cancer.

Additional clinical trial data later this year on Tesaro's key drug, Niraparib, which targets advanced solid tumors in ovarian and breast cancers, could help narrow the valuation gap, the people said.

He concludes by noting the current obsession with Europe, which he dismisses as a «localized tumor.»