Photoswitches inserted into retinal ganglion cells (RGC) of blind mice produce much less variety of response (all evenly red means the cells fire at the same time),
while blind mice with photoswitches inserted into bipolar cells (ON - BC driven) exhibit much more variety in their retinal response to light, closer to that of normal mice.
Not exact matches
If the rods and cones acted as the reset button, then the circadian rhythms of the sighted
mice should hold to the classic pattern
while circadian rhythms of the
blind mice drift away.
He essentially re-created Keeler's
blind mice by shutting down genes essential for the development of rods and cones
while still exposing his subjects to cycles of light and dark.