Sentences with phrase «while dogs with mutations»

Normal kidneys reabsorb the Amino Acid cystine so that only small amounts pass into the urine, while dogs with mutations of both copies of the SLC3A1 gene fail to reabsorb cystine allowing large amounts to pass into the urine, hence the name cystinuria.

Not exact matches

All dogs with AHE were homozygous for this mutation, 15/41 healthy AH control dogs were heterozygous carriers while 26/41 normal healthy AH dogs were wild type.

Washington State U. Vet School says, re ivermectin: «While the dose of ivermectin used to prevent heartworm infection (6 micrograms per kilogram) is safe in dogs with the [MDR1] mutation, higher doses such as those used for treating mange (300 - 600 micrograms per kilogram)[are not].»

These conditions are inherited as X chromosome linked disorders, meaning only male dogs can become affected with the disease, while female dogs, though not clinically affected, can carry the mutation and pass it on to their young.

While this mutation is not, in and of itself, a reason not to breed a dog — even a dog with two copies — the presence of the MDR1 mutation should be viewed as a fault and, over the long term, breeders should work toward reducing the its frequency in the breed.