Analysis of differentially expressed proteins revealed enrichment in cytoskeleton organization, mitochondrial activity and ROS management,
while gene expression analysis revealed enrichment in the epithelial - to - mesenchymal transition pathway.
Proteomic
analysis to profile protein abundance resulted in the identification and relative quantification for 912 proteins with two or more unique peptides and 86 proteins with significant abundance changes after treatment with the neurotoxins,
while microarray
analyses to profile
gene expression revealed 181
genes with significant changes in mRNA after treatment.