Sentences with phrase «while small molecule»

These large molecule drugs differ from traditional pharmaceuticals in that they are usually injected, while small molecule pharmaceuticals are taken in tablet form.

However, while small molecule drugs can cause unwanted side effects because they are easily absorbed in the body, protein drugs can have the opposite problem: they can be too big.

Not exact matches

In fact, while some composting methods have been shown to degrade certain pesticides, heavy metals are an elemental contaminant that does not degrade into smaller, less harmful molecules during the composting process.

While the bumps in Braille signs are a few millimetres apart, the microscope detects bumps that are more than million times smaller — atoms and molecules.

«We have discovered a small molecule compound that shows a profound and prolonged effect on autism - like social deficits without obvious side effects, while many currently used compounds for treating a variety of psychiatric diseases have failed to exhibit the therapeutic efficacy for this core symptom of autism,» said Zhen Yan, PhD, professor in the Department of Physiology and Biophysics in the Jacobs School of Medicine and Biomedical Sciences at UB, and senior author on the paper.

Now, researchers have demonstrated that two iron - containing small - molecule catalysts can help turn certain types of amino acids — the building blocks of peptides and proteins — into an array of potential new forms, even when part of a larger peptide, while preserving a crucial aspect of their chemistry: chirality, or «handedness.»

While small amounts of materials like zinc or silicon are required to produce thin film devices, Cadien says the costs are not insignificant — they can come in at $ 500 or $ 600 per gram and the current processes are wasteful, dosing surfaces with anywhere from 100 to 10,000 times the molecules required.

While analyzing molecules excreted by TRPV1 cells in search of anything that might be itch - specific, Hoon and his colleagues came across a small group of the neurons that produce natriuretic polypeptide b (Nppb), a hormone that regulates heart function and can also act as a neurotransmitter.

tiRNA is a type of small RNA that suppresses global protein synthesis, while rRNA or ribosomal RNA is a type of RNA molecule that enhances protein synthesis.

Fortunately Kappler has an answer in development: a breathable material with micropores small enough to keep out dangerous molecules, but just large enough to let out water molecules, so that I can stay comfortable for hours while I'm wading through pools of glowing green goo.

While its extreme conductivity makes graphene especially suited for small - scale electronics, the authors» primary interest lay in how it accommodated nearly any type of molecule — specifically, ammonia — they placed between it and the ferroelectric layer.

Synthetic doping agents use the larger molecule, while the body normally makes both the larger and the smaller isotopes.

It's still early days, but researchers report that they've discovered a new small molecule that binds selectively to a long - targeted enzyme, halting its role in pain and addiction while not interfering with enzymes critical to healthy cell function.

«We improved the CRISPR - Cas9 system by introducing small molecules that can maintain its precision at locating a point on the genome to cut, while boosting intrinsic repair mechanisms that fuse the DNA back together.»

While his previous method relied almost entirely on small molecules, it still included a minute amount of genetic manipulation; that is, he often required the use of a single gene to enhance his chemical cocktails.

Orally available small molecules would be used for chronic inflammatory indications, while larger molecules present a fast path to IV therapeutics for B - cell malignancies, immune - oncology, and acute inflammatory indications.

While tearing apart even a small molecule like hydrogen may seem difficult enough, controlling the oxidation to create an energy - efficient reaction is even more challenging.

Focused on meeting this urgent unmet medical need, ALS TDI executes a robust target discovery program, while simultaneously operating the world's largest efforts to preclinically validate potential therapeutics; including a pipeline of dozens of small molecules, protein biologics, gene therapies and cell - based constructs.

PV - 10 (rose bengal disodium 10 %), a small - molecule fluorescein derivative, while excluded from normal cells, transits the plasmalemma of cancer cells and accumulates in lysosomes, triggering lysosomal release and complete autolysis within 30 to 60 minutes.

The membrane of the small intestine allows only very small nutrients and fats, proteins and starches which are all broken down to very small particles to enter into the bloodstream, while the larger molecules and many different types of toxic compounds are kept out.

It's very helpful with leaky gut because its molecule is smaller than a red blood cell and will supply amino acids, micronutrients and protein while your dog's gut is healing.

Media Molecule broke off a small team of 15 or so people to make Tearaway while their main team presumably focuses on PS4 development.

While smaller teams within Media Molecule have broken off to create the Tearaway franchise in recent years, there are still a whole lot of people there working on something in secret.

While the front part of a dog's nose is almost entirely committed to respiration, the rest is committed to olfaction — the sense of smell — and since there are hundreds of millions more olfactory receptors in a dog's nose compared to a human's nose, a dog is able to smell more and detect a scent in much smaller quantities: «This means two things: A dog definitely experiences smells, odors — volatile molecules — that we don't,» Alexandra Horowitz, assistant professor at Barnard College and author of Inside of a Dog, told Modern Farmer.