Sentences with phrase «whole cell vaccine»

But the CDC's Martin notes that the United States will probably never use the whole cell vaccine again because of concerns about its possible side effects.

Cyclophosphamide, doxorubicin, and paclitaxel enhance the antigen - specific anti-tumor immune response of GM - CSF - secreting whole cell vaccines in tolerized mice.

Not exact matches

Bringing back the whole - cell vaccine is unlikely, Edwards and Offit say, because of the safety concerns, but Edwards suggests it might be possible to modify a new whole - cell vaccine that's less reactive or to add antigens to the acellular vaccine.

Managing pertussis outbreaks Aside from the difference in antigens, though, scientists remain unsure what made the whole - cell vaccine so effective.

«Even with the new immunological studies, we can't tell what's special about the whole - cell vaccine that makes it better,» says Kathryn Edwards, the director of the Vanderbilt University School of Medicine Vaccine Research vaccine that makes it better,» says Kathryn Edwards, the director of the Vanderbilt University School of Medicine Vaccine Research Vaccine Research Center.

The older vaccine, DTP, used whole cells of the pertussis bacterium but had more dramatic side effects, often causing high fevers and sometimes fever - induced seizures.

Researchers used IL - 15 to develop a whole tumor cell vaccine to target breast (TS / A) and prostate (TRAMP - C2) cancer cells in animal models; results showed that tumor cells stopped growing after the vaccine was introduced and that beneficial effects were enhanced further when IL - 15Rα was co-produced by the vaccine cells.

A pancreatic cancer vaccine could be made of whole pancreatic cancer cells, treated so they can't replicate, but modified to present certain molecules on the surface of those cells.

It exposes the immune system to only a handful of bacterial proteins, and it may be that exposure to more — as occurred when people were inoculated with the whole - cell vaccine — is more powerful.

An Australian study recently reported that kids who were given the acellular vaccine as infants were more than three times as likely to get pertussis between 2009 and 2011 than were those who received the whole - cell version.

Jason Harris, from Massachusetts General Hospital in Boston, USA, and colleagues are studying a bivalent whole cell oral (BivWC) cholera vaccine produced in India that received pre-approval by WHO in 2011.

The current acellular vaccine, purified down to three antigens, was introduced in 1997 to replace the previous whole - cell vaccine, after side effects such as fever and crying dissuaded many parents from starting or completing the three doses of vaccine required by six months of age.

It gives an overview of the whole of the topic - communicable disease examples, body's front line defences, white blood cells and immunity, vaccines, anitbiotics and resistance, and drug development.It looks great in A3.

The problem is that there are two types of vaccines (whole cell / killed Lyme or subunit).