Sentences with phrase «whole chromosomes»

Others gained or lost whole chromosomes, but gained or lost fractions of other chromosomes.

Now the same strategies can be used to create whole chromosomes in order to investigate chromosome behavior

Instead of blasting away at whole chromosomes, they extracted mRNA from 37 different human organs and tissues, copied it back into DNA, and sequenced that.

Nearly three - fourths of embryos examined contained at least one cell with either partial or whole chromosome aberrations, similar to findings in human in vitro fertilized embryos.

He provides additional detail on whole chromosome versus molecular and biochemical genetic tests, including cytogenetic tests (karyotyping and fluorescent in situ hybridization (FISH) tests) and molecular tests.

Variations in the normal ploidy are referred to as aneuploidy (gain or loss of whole chromosomes) and polyploidy (gain of multiple sets of chromosomes).

«Cancer cells have this fast way of gaining and losing whole chromosomes, adapting in the face of cancer therapy,» says Swanton.

«This technology will allow us to paint a whole chromosome and look at it live and really follow it... as it goes through developmental transitions, for example in an embryo,» study co-author Rebecca Heald, a molecular and cell biologist at UC Berkeley, said in a statement.

We took millions of copies of the whole chromosome from Haemophilus, he says, and we used sound waves to break them apart into tiny pieces.

In principle, once all the fragments had been sequenced, the researchers could piece together the whole chromosome the way you might piece together a single panoramic photograph from a series of overlapping frames.

In the clincher, Nausica Arnoult, a postdoc in the Karlseder lab and one of the study's co-authors, took advantage of a fluorescent tag that others had embedded into one chromosome's telomeric end and then used a whole chromosome imaging method called FISH to track where the tag went over time.

«They've completely lost a whole chromosome in one generation,» says Holleley.

They discovered that the number of tumor suppressor genes or oncogenes in a chromosome correlated with how often the whole chromosome or part of the chromosome was deleted or duplicated in cancers.

Down Syndrome belongs to the group of conditions called «aneuploidies», defined by an abnormal loss or gain of genetic material, i.e. fragments of chromosomes or whole chromosomes.

These erratic, small extra nuclei, which contain fragments, or whole chromosomes that were not incorporated into daughter cells after cell division, are associated with specific forms of cancer and are predictive of poorer prognosis.