Sentences with phrase «whole genome analysis»

The first whole genome analysis of an octopus reveals unique genomic features that likely played a role in the evolution of traits such as large complex nervous systems and adaptive camouflage.

The directed support serves to facilitate use and implementation of the new opportunities for whole genome analysis, and to ensure that Swedish researchers are well equipped to take advantage of the increasingly demanding datasets.

As summarized in this article, the scientists of the BDGP believes that the benefits of the whole genome analysis can best be realized if it is coupled with powerful genetic tools.

Association testing was performed using the PLINK whole genome analysis [36].

Visual traits for each individual were compared to whole genome analysis results to identify the genes driving differences in appearance.

Their technique, however, relied on whole genome analysis of methylation that costs upward of $ 1000 per sample.

«I think what's interesting about combining whole genome analysis and histopathology is that we can study the tumor at multiple levels,» said co-author Rakopoulos.

Our lab is equipped with the renowned Illumina MiSeq desktop sequencer and the Illumina HiSeq2500, which enable rapid and effective targeted and whole genome analyses.

Whole genome analyses can identify maladaptive genes responsible for traits associated with inbreeding depression, such as low sperm mobility, cryptorchidism, and kinked tails, and prevent the accumulation of these traits in the population.

Not exact matches

By increasing the speed and accuracy for NGS data analysis like whole genome sequencing (WGS), our computing platform makes it easier to discover links between DNA sequence variations and human disease.»

However, the results of more recent phylogenetic analyses, derived from comparisons between sequences of specific genes and of whole genomes, seemed to point to Ctenophora as the first group that parted company with the lineage from which the rest of the animal kingdom (including sponges) evolved.

Using advanced sequencing technologies, University of Oklahoma anthropologists demonstrate that human DNA can be significantly enriched from dental calculus (calcified dental plaque) enabling the reconstruction of whole mitochondrial genomes for maternal ancestry analysis — an alternative to skeletal remains in ancient DNA investigations of human ancestry.

Human DNA can be significantly enriched from dental calculus (calcified dental plaque) enabling the reconstruction of whole mitochondrial genomes for maternal ancestry analysis — an alternative to skeletal remains in ancient DNA investigations of human ancestry.

Professor Ed Feil, joint lead author from the Milner Centre for Evolution, at the University of Bath, said: «We've developed user - friendly analysis software that demonstrates how whole genome sequence data can be a powerful tool for pan-European surveillance of MRSA and other important pathogens.

While several studies in the intervening years have investigated whether particular genes were responsible for modifying HD onset, this is the first to employ genome - wide association (GWA) analysis, which scans an individual's whole genome to identify chromosomal regions containing variants that are associated with the disease traits that are being studied.

Eager to get the record straight, Laurent Frantz, now a bioinformaticist at the University of Oxford in the United Kingdom, carried out sophisticated computer analyses of 103 whole genomes sequenced from wild boars and domesticated pig breeds from all over Europe and Asia.

This is one of the first population genomics analyses to use high - coverage whole - genome sequencing in pigs, each individual has been sequenced more than 20-fold depth with the genome coverage of 95 %.

Using technologies like whole genome or whole exome (the protein - coding portion of the genome) sequencing requires specialized equipment and advanced data analysis and is still relatively expensive.

An analysis of whole - genome sequences from more than 5,000 people has unearthed 18 new candidate genes for autism.

But analysis of whole genomes — the gold standard for population studies — was scanty for many key parts of the world.

The research, which formed part of a vast study carried out over the past four years by the international Avian Phylogenomics Consortium, involved the analysis of the whole genome structure of the chicken, turkey, Pekin duck, zebra finch and budgerigar.

The study is the largest analysis of whole genomes from people with autism and their family members to date.

The high degree of similarity between the mouse and human genomes is demonstrated through analysis of the sequence of mouse chromosome 16 (Mmu 16), which was obtained as part of a whole - genome shotgun assembly of the mouse genome.

Together, all five RMs serve as a collection of well - characterized, whole genome standards that can tell a laboratory how well its DNA sequencing processes are working by measuring the performance of the equipment, chemistry and data analysis involved.

Several of the insights from the analysis of the whole genome confirm what researchers had thought.

It involved the analysis of 5,205 whole genomes from families affected by autism — making it the largest whole genome study of autism to date.

TMWG allows customers to access the power of whole - genome epigenetic information in an integrated, cost - effective solution combining state - of - the art sample preparation and DNA sequence analysis.

The TrueMethyl Whole Genome (TMWG) integrated workflow system for processing DNA samples includes all - in - one reagents for sample conversion, library creation, and indexing, combined with bioinformatics tools to enable accurate DNA modification analysis through next - generation sequencing methods.

We therefore performed unsupervised clustering analyses with ADMIXTURE (SNP array data; Supplementary Fig. 15) and NGSadmix (whole - genome data; Fig. 4 and Supplementary Fig. 16)(Supplementary Note 9) and found that, unlike contemporary European village dogs, all three ancient genomes possess a significant ancestry component that is present in modern Southeast Asian dogs.

His analysis was backed up by Nicholson Price, an academic fellow at Harvard Law School in Cambridge, Massachusetts, who found that few, if any, DNA patents would be infringed by companies or clinics sequencing whole genomes of individuals for medical insight.

Therefore, we present analysis of ∼ 9 × coverage whole genomes of two dog samples from Germany dating to the Early and End Neolithic (∼ 7,000 years old and ∼ 4,700 years old, respectively).

Bootscanning analysis revealed no evidence for recombination of TMAdV with other adenoviruses at either the whole - genome or individual gene level (Fig.

NORMAN — Using advanced sequencing technologies, University of Oklahoma anthropologists demonstrate that human DNA can be significantly enriched from dental calculus (calcified dental plaque) enabling the reconstruction of whole mitochondrial genomes for maternal ancestry analysis — an alternative to skeletal remains in ancient DNA investigations of human ancestry.

We aim to build a novel liquid biopsy platform for the cases with a low burden in plasma using a sensitive whole genome, whole methylome and epigenetics analyses.

The Genome Analysis Centre becomes a UK centre of excellence for whole genome mapping techGenome Analysis Centre becomes a UK centre of excellence for whole genome mapping techgenome mapping technology

• Mouse whole genome scanning The unit offers microsatellite and SNP based Genome Scanning Services for gene identification projects, based on linkage analysis, offering coverage for a number of mouse strains (i.e. C57BL6, DBA2J, CBA, 129S6, 129P2), as well as bioinformatic analysis using suitable mouse genetic sofgenome scanning The unit offers microsatellite and SNP based Genome Scanning Services for gene identification projects, based on linkage analysis, offering coverage for a number of mouse strains (i.e. C57BL6, DBA2J, CBA, 129S6, 129P2), as well as bioinformatic analysis using suitable mouse genetic sofGenome Scanning Services for gene identification projects, based on linkage analysis, offering coverage for a number of mouse strains (i.e. C57BL6, DBA2J, CBA, 129S6, 129P2), as well as bioinformatic analysis using suitable mouse genetic software.

The most significant of these was the HiSeq X Ten, a 10 - instrument «factory installation» that enabled the most cost - effective human whole genome sequencing to date: 18,000 genomes per year at a consumables cost of just over $ 1,000 each (note: this does not include the costs of data storage, analysis, or the $ 10 million buy - in).

Utilize turn - key analysis pipelines and visualization tools for investigating variation within whole genome, exome and single cell samples.

Taking advantage of this relevant cell model, we provided, by using a whole - genome transcriptional analysis, a list of DM1 specific biomarkers that could be considered as a robust DM1 signature.

We will take the user from a beginner level understanding to one that can analysis multiple whole human genomes and derive meaningful clinical results using the latest methodologies.

As an example, the ICGC / TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) project, co-led by our group, is leveraging cloud solutions to globally standardize and analyze cancer genomics data, with the aim of uncovering commonalities and differences between molecular disease mechanisms in disparate cancer entities.

We expanded on our genome sequencing efforts to include efforts in whole genome gene expression analysis and functional analysis of genome variation.

Parallel whole - genome microarray analysis was used to determine the transcriptome in matched samples.

HLI and UC San Diego have signed a collaborative research agreement to develop protocols and procedures to enable whole genome, microbiome and tumor sequencing and analysis of consenting UC San Diego research patients.

JOURNAL: B. vonHoldt et al. «Whole - genome sequence analysis shows that two endemic species of North American wolf are admixtures of the coyote and gray wolf.»

Made possible through whole genome sequencing + bioinformatics science and analysis https://t.co/IbzGurrMPp

Next generation sequencing was to include whole exome sequencing (WES) and whole genome sequencing (WGS) and analysis on large numbers of well characterized subjects to identify AD risk and protective gene variants.

Next generation sequencing includes whole exome sequencing (WES) and whole genome sequencing (WGS) and analysis on large numbers of well characterized subjects to identify AD risk and protective gene variants

«Analysis of the bread wheat genome using whole genome shotgun sequencing» is published online in Nature on November 29, 2012.

Since our analyses are often based on multiple genome alignments, we are also interested in improving whole genome alignment methods.