«The physical symptoms that affect people with Parkinson's — including tremors and rigidity of movement — are caused by an imbalance between two types of medium spiny neurons in the brain,» said Dr. Kreitzer,
whose lab studies how Parkinson's disease affects brain functions.
«We are trying to fill the knowledge gap between the infection and potential neurological defects,» says first author Hengli Tang, the team's virologist
whose lab studies RNA viruses like Zika, Dengue, and hepatitis C virus.
Burke,
whose lab studies the genomic basis of evolutionary divergence within the sunflower family, was involved in the genetic mapping upon which the genome assembly was based and oversaw the whole genome re-sequencing of the 80 sunflower lines described in the paper.
«Laminins function as attractive chemical cues for haptotaxis of axonal growth cones,» explains NAIST Prof. Naoyuki Inagaki,
whose lab studies how forces are generated in the cellular microenvironment to create directed axonal migration.
Sabatini and Yilmaz,
whose labs study the relationship between diet and cancer, set out to uncover the cellular mechanisms underpinning the enhanced risk of colon cancer.
Not exact matches
According to a
study by George Washington University and Zignal
Labs, Sanders is the only candidate
whose «echo» across the Internet has actually increased since his initial announcement of his bid for the presidency.
Michael Kaplitt, a neurosurgeon at Weill Cornell Medical College in New York,
whose lab develops gene therapies for brain disorders, teamed up with Greengard and other colleagues in the new
study.
Jonathan Storm, a behavioural ecologist now at the University of South Carolina Upstate, in Spartanburg, briefly exposed
lab - grown female crickets to wolf spiders
whose fangs had been immobilised with wax, then
studied the behaviour of their subsequent offspring.
For this
study, Tomasson collaborated with nanomedicine expert Gregory M. Lanza, MD, PhD, the Oliver M. Langenberg Distinguished Professor of Science and Practice of Medicine,
whose lab synthesized and modified a compound discovered by Edward V. Prochownik, MD, PhD, of the University of Pittsburgh.
MSSM neuroscientist Deanna Benson,
whose lab collaborated with Gazzaley on a
study during his graduate training, remembers having initial reservations about him because he seemed overly casual.
How these capabilities might play out in the real world is still a big question, says Ring Cardé,
whose lab at the University of California, Riverside also
studies odor and other cues mosquitoes use to hunt down a meal.
This is one of the diseases
whose development researchers will now be able to
study in the
lab.
Xinde Zheng, a research associate in the Hunter
lab, was already
studying the properties of cells affected by Leigh syndrome,
whose inherited neurodegeneration is caused by a mutation in mitochondrial DNA that reduces ATP production.
Kipnis also saluted the «phenomenal» surgical skills of Igor Smirnov, a research associate in the Kipnis
lab whose work was critical to the imaging success of the
study.
«Because of the Harvard Stem Cell Institute, we were able to work with other researchers to make patient cells into any type of neuron,» said Young - Pearse,
whose lab spent two years fine - tuning protocols with collaborators to generate the neurons needed for her early onset Alzheimer's
study.
Without enough oxygen, the yeast may be unable to produce the metabolic changes scientists think are necessary to prolong life, say MIT molecular biologist Leonard Guarente,
whose lab pioneered the
study of caloric restriction in yeast.
Still the
study is «an important first step to show that manipulating AMPK - nNOS signaling at least has the potential to help muscle function in muscular dystrophy,» says Michele
whose lab at the University of Michigan Cardiovascular Research Center focuses on inherited forms of skeletal and cardiac diseases.
Her experiments were conducted on C. elegans roundworms,
whose short lifespans and well - characterized nervous systems make them a preferred species for quick - turnaround
lab studies.
«You see the object on a monitor and then you can point and click and take a sample from a particular spot and the robot will go there,» said Facundo Fernandez, a professor in the School of Chemistry and Biochemistry,
whose lab led the
study.
«Obesity is generally associated with leptin resistance,» says Friedman,
whose lab produced the new
study.
«This is essentially a recipe for how to make human inner ears from stem cells,» said Dr. Koehler, lead author of the
study and
whose research
lab works on modeling human development.
The work was led by reproductive biologist Michael Skinner of Washington State University in Pullman,
whose lab has been
studying vinclozolin, a fungicide used in the wine industry.
«These rich and large phenome data remain, however, largely unexploited, as they are difficult to access and the tools to analyze them require advanced skills,» says Johan Auwerx,
whose lab at EPFL led the
study with colleagues from Germany, Netherlands, and the US, as well as EPFL professors Kristina Schoonjans and Stephan Morgenthaler.
«A key aspect of this
study was the use of high - resolution metabolomic tools based on mass spectrometry,» said Facundo M. Fernández, a professor in the School of Chemistry and Biochemistry,
whose lab ran the mass spectrometry analysis.
But making chimeras with human organs
whose development can be
studied is more likely to succeed than the technique researchers have been trying for years: coaxing stem cells growing in
lab dishes to become three - dimensional, functional tissues and organs.
«The right drug at the right dose, taken for the right duration, is life - saving,» says Alison Halpin, a molecular epidemiologist at the CDC
whose lab produced the
study.
A Cornell Food and Brand
Lab study found that women who stored soft drinks on the counter weighed 24 to 26 pounds more than women
whose counters were free of sugary beverages.
They have a number of doctors on staff at eHarmony
Labs who are experts in their fields of
study and
whose purpose is to research and improve the matching system.
We would like to thank the Pomona CARE
Lab research assistants
whose assistance was invaluable and the mothers and children who participated in the
study.