On one side are the prokaryotes — bacteria and archaea —
whose simple cells are not much more than tiny bags of chemicals.
Not exact matches
The consensus on the evolution of primitive life is that
simple life forms (prokaryotes, organisms
whose cells lack a distinct nucleus) inhabited the Earth about 3 - 4 billion years ago, eukaryotic
cells (those with a nucleus which contains the genetic material) emerging 2 - 3 billion years ago.
As an example of a disease
whose genetic basis not only is felt to be much
simpler than that of malignancies, but also is affected by host genomic and environmental complexities, consider sickle
cell disease.
By developing a
simple chemically defined culture system permitting efficient differentiation of numerous human iPS
cell lines toward
cells of a mature hepatic state, we now demonstrate the possibility of modeling groups of diseases of non-neuronal origin
whose phenotypes are a consequence of complex protein dysregulation within adult
cells.