Sentences with phrase «whose smaller tumors»

Not exact matches

He was part of a team that recognized that only about 10 % of patients with NSCLC responded to the small molecule erlotinib — those whose tumors harbored mutations in the gene encoding EGFR.

Vescor, advised by its scientific founders White and Kimmelman, whose research has shown inhibition of autophagy can dramatically impact tumor growth in pre-clinical models, will develop small molecule inhibitors of a number of protein targets at critical nodes of the autophagy cascade, perform investigational new drug (IND) enabling studies, and move these into clinical development.

The researchers, studying women with node - negative breast cancer — the small, early tumors sought by mammography — found that by adding E-cadherin to other biomarkers that they have studied they are able to distinguish those patients with a 90 percent long - term survival from those whose survival is only 44 percent.