ASHG 2016: Researchers Perform Large Genome -
wide Analysis of Multiple Sclerosis ASHG Press Release — October 18, 2016
Genome -
wide analysis of CNVs revealed that a single copy of the mdr1 gene on chromosome 5 and a novel amplification of the plasmepsin 2 and plasmepsin 3 genes on chromosome 14 also associate with raised piperaquine IC
50 s.
Brain -
wide analysis of electrophysiological diversity yields novel categorization of mammalian neuron types by Shreejoy J Tripathy, Shawn D. Burton, Matthew Geramita, Richard C. Gerkin, and Nathaniel N. Urban.
In a genome -
wide analysis of up to 17 503 participants in PROMIS, we identified genetic variants associated with either apolipoprotein (a) isoform size or lipoprotein (a) concentration.
Kim et al. have performed a genome -
wide analysis of target promoters for nine transcription factors, namely Oct4, Sox2, Klf4, c - Myc, Nanog, Dax1, Rex1, Zpf281, and Nac1 [64].
Comprehensive population -
wide analysis of Lynch syndrome in Iceland reveals founder mutations in MSH6 and PMS2 Haraldsdottir S et al Nat Commun.
In the first study to run a genome -
wide analysis of Short Tandem Repeats (STRs) in gene expression, a large team of computational geneticists led...
Leaf senescence in Arabidopsis thaliana.Genetic and genome -
wide analysis of histone modifications that accompany leaf senescence.
According to Dr Adil Mardinoglu, SciLifeLab Fellow and leader of the systems biology effort in the project: «We are now in possession of incredibly powerful systems biology tools for medical research, allowing, for the first time, genome -
wide analysis of individual patients with regards to the consequence of their expression profiles for clinical survival.»
A systematic genome -
wide analysis of zebrafish protein - coding gene function.
Julia Winter (Zerial, MPG)-- «Genome -
wide analysis of membrane trafficking in polarised epithelial cells in the C.elegans intestine» (2008)
Birgit Kagermeier - Schenk (Weidinger, TUD)-- «Genome -
wide analysis of Wnt / beta - catenin target genes in zebrafish embryogenesis and characterization of a novel modifier of Wnt signaling pathways» (2010)
An unbiased genome -
wide analysis of zinc - finger nuclease specificity.
Genome -
wide analysis of variance (ANOVA) revealed that germline SNPs / CNVs and somatic CNAs influenced > 39 % of gene expression probes, roughly half acting in cis and half in trans.
«The results of our study speak to the evolutionary origins of obesity and provide new targets to understand the polygenic nature of obesity in a unique model system,» according to the study, «Genome -
Wide Analysis of Starvation - Selected Drosophila melanogaster — A Genetic Model of Obesity.»
Previous genetic studies have examined the association of aspirin, NSAIDs, or both with colorectal cancer according to a limited number of candidate genes or pathways.6 - 10 Thus, to comprehensively identify common genetic markers that characterize individuals who may obtain differential benefit from aspirin and NSAIDs, we conducted a discovery - based, genome -
wide analysis of gene × environment interactions between regular use of aspirin, NSAIDs, or both and single - nucleotide polymorphisms (SNPs) in relation to risk of colorectal cancer.
«In the current study, using a genome -
wide analysis of DNA methylation, we identified a few PPARα target genes that underwent ligand - activated PPARα - dependent DNA demethylation during the perinatal period and whose DNA methylation status persists into adulthood,» explains a corresponding author Koshi Hashimoto.
The researchers, including postgraduate students Miaolin Chen at Shanghai Jiao Tong University and Deborah Devis at the University of Adelaide's Waite campus, performed a genome -
wide analysis of potential pollen allergens in two model plants, Arabidopsis thaliana (thale cress) and rice by comparing those results among 25 species of plants ranging from simple alga to complex flowering plants.
The researchers performed genome -
wide analysis of nasal epithelial cells collected from children experiencing acute asthma exacerbation.
Scientists from the Biogerontology Research Foundation (BGRF), a UK - based charity founded to support aging research and address the challenges of a rapidly aging population, propose a new concept for signalome -
wide analysis of changes in intracellular pathways, called OncoFinder, which allows for accurate and robust cross-platform analysis of gene expression data.
Last year,
a wider analysis of over 1,200 business sites and 700 companies found that the median site reaped $ 14 in returns for every $ 1 invested.
Conducting the first large - scale, genome -
wide analyses of ancient human remains from the Near East, an international team led by Harvard Medical School has illuminated the genetic identities and population dynamics of the world's first farmers.
Genome -
wide analyses of hundreds or thousands of genes can also be used to pinpoint candidate genes or suites of genes.
It also means contributing to
the wider analysis of the problem — through research and technology and through engagement in the search for the best public policy mechanisms, the actions which can produce the right solutions for the long - term common interest.
Not exact matches
According to MarketingProfs.com, B2B organizations that exceed annual revenue goals are more likely than worse - performing organizations to use a
wide range
of sources to develop buyer personas, including interviews, surveys, and competitive
analyses.
Assistant U.S. Attorneys do their own copying, and in one recent sting it was Sandy — one
of the unit's two secretaries — who did the records
analysis that broke the case
wide open.
Enders
Analysis, in a
wide - ranging note on blockchain and its use across various industries, says that a lot
of the capabilities
of blockchain are exaggerated or misunderstood and that existing technology can often perform the same roles.
He supports this claim by pointing out how da Vinci's portraits defy facile
analysis — how the interpretation
of his portraits» moods is
wide open to the imagination.
«However, it is important to note that they are but one input into a
wider set
of analyses.»
Personal Capital offers a
wide range
of investment
analysis tools including an early retirement calculator that is absolutely free.
In - depth
analyses of elite and public opinion survey data from the United States and China on a
wide range
of security issues provide nuanced and far - reaching insights into the potential effects
of these attitudes on the U.S. - China relationship.
For over 25 years, he was the leader
of a team
of investment professionals involved in a
wide array
of investment activities including stock and bond investment, commodity hedging, merger and acquisition
analysis, and venture capital investing.
In those roles, he provided economic
analyses and other technical support to the Commission and other SEC Divisions and Offices on a
wide range
of rulemaking, compliance, and enforcement matters.
Institutional Investor's Alpha is a financial blog focused on providing a
wide array
of news,
analysis, and opinion content.
Moreover, our
analysis shows that the cumulative income generated over the period in which the balance sheet has been unusually large is likely to exceed normal levels under a
wide range
of scenarios.
Since EBSA's attempts to secure data from the industry about the impact on IRA investors
of conflicts
of interest faced by brokers and advisors who advise on IRAs have failed, Borzi said the department is using «a
wide variety
of data sources» to compile its cost / benefit
analysis on IRAs.
Since 1981, the Institute has provided objective
analysis and concrete solutions to a
wide range
of international economic problems.
That's because a
wide number
of variables, many
of which can't be predicted, can make the markets move in one direction or the other and render useless even the best research and
analysis.
The
wide ranging discussion covered several topics, including the recent proxy season, perceptions
of proxy advisors, positive and negative trends in governance practices at companies, and how Glass Lewis approaches its
analysis.
Technical
analysis show that Zencash / Bitcoin appears to have created a
wide upward channel that began on October 9, 2017 when it created a low
of 0.0010495.
«A «failure
of diversification» during the global financial crisis has prompted
wider use
of factor
analysis across portfolios and reduced reliance on simplistic asset allocation measures.
Stephen has been involved in over 70 different research projects covering a board variety
of wealth manager types, service providers to the sector, a
wide array
of international jurisdictions and a diverse project focus such as market
analysis and sizing, competitive intelligence and benchmarking, market entry strategy and client, advisor and intermediary insight.
He is an experienced user
of R, Excel, SPSS and Eviews and has mastered a
wide variety
of data
analysis and analytics skills.
In fact, a CNBC
analysis found that the difference between earnings per share growth and gross domestic product expansion in the first quarter is the
widest since the third quarter
of 2011.
A bounce from there tested the $ 290 level, which
of course is a very important level, as it was the bottom
of consolidation, but it looks likely that we are entering a
wider consolidated... Continue reading ETH / USD and ETH / BTC Technical
Analysis November 3 2017
A culture
of bullying has taken over in this area, and the idea
of academic freedom,
wide enquiry, and genuine debate and
analysis is no longer seen as essential in university life.
The new site will have the same insightful
analysis and in - depth reporting that you're used to, but it will also enable us — and, more importantly, you — to navigate through a
wider array
of videos, articles and columns from our team
of reporters and editors around the globe.
The data presented in Pew's latest,
wide - ranging
analysis are based primarily off
of estimates, since the government doesn't track specific religious affiliation for new permanent residents.
The truncated idea
of God that figures in the
analysis, and in much
of the rest
of the church's ethical reasoning, automatically precludes or minimizes the investigation
of certain lines
of thinking, and leads to reductionistic treatments
of a
wide range
of issues.
Her book does provide a
wide - ranging introduction to the study
of rhetoric and a clear and useable method for textual
analysis.