Sentences with phrase «wide association study on»

He is involved in the first genome - wide association study on bipolar I disorder in the Han - Chinese population.

Not exact matches

In genome - wide association studies (GWAS), researchers focus on typical variations in genomes, so - called SNPs (single nucleotide polymorphisms).

Available in Volume 168, Issue 8 of the American Journal of Medical Genetics: Neuropsychiatric Genetics, the paper, titled, «Using the Coriell Personalized Medicine Collaborative Data to Conduct a Genome - Wide Association Study of Sleep Duration,» draws on data collected from Coriell study participants to establish its findStudy of Sleep Duration,» draws on data collected from Coriell study participants to establish its findstudy participants to establish its findings.

All of these studies were genome - wide association studies (GWAS) based on millions of genetic variants called Single Nucleotide Polymorphisms (SNPs).

The research, led by Knut Wittkowski, biostatistician in the Center for Clinical and Translational Science at The Rockefeller University Hospital, is a twist on a traditional data - mining technique known as a genome - wide association study.

The researchers acknowledge the Ovarian Cancer Association Consortium and the Genetic Associations and Mechanisms in Oncology (GAME - ON): a National Cancer Institute Post-Genome Wide Association Study Initiative (U19 - CA148112).

The software allowed them to compare the results of the more than 1,400 genome - wide association studies (GWAS) that have been published on the topic so far.

Genome - wide association studies generally rely on genetic variations called single - nucleotide polymorphisms, or SNPs (pronounced «snips»).

In their new study, the team performed a genome - wide association study (GWAS) on a cohort of 235 Labrador retrievers, together with an independent replication cohort.

To reduce false positives when identifying genetic variations associated with human disease through genome - wide association studies (GWAS), Dartmouth researchers have identified nine traits that are not dependent on P values to predict single nucleotide polymorphisms (SNP) reproducibility as reported in Human Genetics on October 2, 2014.

In a 7 - year study at a Boston elementary school where half the students are English Language Learners (ELL), setting a school - wide goal of improved writing skills and using a genres - based instructional method improved the performance of ELL students on state and internal assessments, according to Boston College Lynch School of Education Professor Maria E. Brisk, who presents her findings today at the American Educational Research Association annual meeting.

The authors of the paper, which appears in the 29 August issue of PLoS Genetics, work on large genome - wide association studies.

The research team, following up on a previous genome - wide association study by researchers at Baylor College of Medicine, investigated genetic variations in a protein called FBN - 1, which is essential for a strong arterial wall.

The researchers integrated these data with results from a prior Psychiatric Genomic Consortium genome - wide - association study, based on clinician - vetted diagnoses of more than 20,000 patients and controls of European ancestry.

Because the risk is inherited and varies in this way, the SNP, located on chromsome 11, had never been linked to T2D even though it had been genotyped in large, traditional genome - wide association studies (GWAS).

Another interesting local network structure is centered around CLU, a gene shown to be involved in AD based on genome - wide association studies, with genes in the integrin family, involved in cell adhesion, clustered around CLU.

Following up on findings from genome - wide association studies, researchers identify two mechanisms by which disruptions in the gene SLC16A11 may play a role in type 2 diabetes

Following up on findings from a an earlier genome - wide association study (GWAS) of type 2 diabetes (T2D) in Latinos, researchers from the Broad Institute of MIT and Harvard and Massachusetts General Hospital (MGH) traced an association detected in that study to variants in a specific gene, SLC16A11, and uncovered two distinct mechanisms by which those variants disrupt the gene's function in liver cells, possibly contributing to the pathogenesis of T2D.

By examining the results of genome - wide association studies (GWAS) in conjunction with experiments on mouse and human red blood cells (RBCs), researchers in the lab of Whitehead Institute Founding Member Harvey Lodish have identified the protein cyclin D3 as regulating the number of cell divisions RBC progenitors undergo, which ultimately affects the resulting size and quantity of RBCs.

Catalyse a new generation of research on the genetic basis of drug resistance and of other forms of biological adaptation in pathogen populations, by providing a standard analytical framework for the design and interpretation of genome - wide association studies.

Building on multiple genome - wide association studies, researchers identify a distant regulator of the EDN1 gene that influences risk for five vascular disorders.

The paper, «Genome - wide association study identifies sequence variants on 6q21 associated with age at menarche,» is published in the online edition of Nature Genetics, at www.nature.com/ng, and will be published in an upcoming print edition of the journal.

deCODE MI ™ The deCODE MI ™ test detects two SNPs located on chromosome 9p21, discovered by deCODE and which various genome - wide association studies have confirmed as the highest impact genetic risk factor for heart attack and coronary artery disease identified to date.

Genome - wide association study identifies sequence variants on 6q21 associated with age at menarche.

Researchers will use GTEx data to follow up on findings from genome - wide association studies and as a resource for the general study of gene expression networks.

Using individual - level data from 335,464 participants in the UK Biobank and summary association results from seven large - scale genome wide association studies, we examined the effect of this nitric oxide signaling score on cardiometabolic and other diseases.

Genome - wide association study of migraine implicates a common susceptibility variant on 8q22.1.

The findings by Anne McTiernan, M.D., Ph.D., and colleagues — from the first study to look at the impact of a wide range of self - monitoring and diet - related behaviors and meal patterns on weight change among overweight and obese postmenopausal women — are published online in the Journal of the Academy of Nutrition and Dietetics (formerly the Journal of the American Dietetic Association).

An Online Publishers Association study showed U.S. residents paid $ 600 million on online dating and personals in 2006, capturing the largest segment of paid content anywhere on the World Wide Web.

Biopsy results from the affected puppy were sent to the University of California, San Diego - Comparative Neuromuscular Laboratory where an inflammatory and necrotizing myopathy of undetermined origin was concluded and a GWAS study (genome - wide association study) was recommended on their report of March 7, 2016.